Survival study and clinicopathological evaluation of trichilemmal carcinoma

Zhuang,Shi-Min; Zhang,Ge-Hua; Chen,Wen-Kuan; Chen,Shu-Wei; Wang,Li-Ping; Li,Huan; Song,Ming

doi:10.3892/mco.2013.74

May-June 2013 Volume 1 Issue 3

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May-June 2013 Volume 1 Issue 3

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Article

Survival study and clinicopathological evaluation of trichilemmal carcinoma

Authors:
- Shi-Min Zhuang
- Ge-Hua Zhang
- Wen-Kuan Chen
- Shu-Wei Chen
- Li-Ping Wang
- Huan Li
- Ming Song
View Affiliations / Copyright

Affiliations: Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China, Department of Head and Neck Surgery and State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China
Pages: 499-502
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Published online on: January 30, 2013

https://doi.org/10.3892/mco.2013.74
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Abstract

Trichilemmal carcinoma (TC) is a rare malignancy, commonly located on the scalp, forehead and neck, trunk or the upper extremities. The aim of this study was to investigate the clinicopathological characteristics and prognostic factors of TC, and to determine an optimal treatment strategy for these patients. Consecutive patients who were admitted to the Sun Yat-sen University Cancer Center between 1998 and 2012 were included in this retrospective study. The key prognostic factors affecting survival were lymph node metastasis and surgery margin. Multivariate analysis demonstrated that there was no risk factor for patient survival. Surgery margin and lymph node metastasis were the prognostic factors that influenced the treatment outcome. Simple excision with 1 cm margins is safe, cost‑effective and effective for the treatment of TC. Additionally, postoperative follow-up of the patient in order to facilitate early diagnosis of recurrence and distant metastasis is necessary. Systemic chemotherapy should be considered in the case of patients with distant metastases.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Survival study and clinicopathological evaluation of trichilemmal carcinoma

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