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Molecular and Clinical Oncology
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Article

Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site

  • Authors:
    • Lanfang Yu
    • Xiaoxiao Ge
    • Sui Huang
    • Yanli Wang
    • Peng Shen
  • View Affiliations / Copyright

    Affiliations: Department of Medical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China, Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
  • Pages: 503-506
    |
    Published online on: February 27, 2013
       https://doi.org/10.3892/mco.2013.79
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Abstract

Retroperitoneal squamous cell carcinoma (SCC) of unknown origin is uncommon. It is extremely rare when the primary site detected in the esophagus after 18 months. A 59‑year‑old female patient with waist pain was initially diagnosed as retroperitoneal metastatic SCC of occult origin. Six cycles of chemotherapy with cisplatin, paclitaxel and 5‑fluorou­racil were administered and clinical complete response was observed. The primary site was detected in the esophagus after 18 months and the overall survival (OS) was 28 months. To the best of our knowledge, this is the first case of esophageal squamous cell carcinoma (ESCC) initially presenting as a metastatic site with long progression‑free survival (PFS) and OS. In conclusion, the different biological characteristics and complete response to first‑line chemotherapy likely contribute to relatively long PFS and OS.
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Copy and paste a formatted citation
Spandidos Publications style
Yu L, Ge X, Huang S, Wang Y and Shen P: Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site. Mol Clin Oncol 1: 503-506, 2013.
APA
Yu, L., Ge, X., Huang, S., Wang, Y., & Shen, P. (2013). Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site. Molecular and Clinical Oncology, 1, 503-506. https://doi.org/10.3892/mco.2013.79
MLA
Yu, L., Ge, X., Huang, S., Wang, Y., Shen, P."Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site". Molecular and Clinical Oncology 1.3 (2013): 503-506.
Chicago
Yu, L., Ge, X., Huang, S., Wang, Y., Shen, P."Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site". Molecular and Clinical Oncology 1, no. 3 (2013): 503-506. https://doi.org/10.3892/mco.2013.79
Copy and paste a formatted citation
x
Spandidos Publications style
Yu L, Ge X, Huang S, Wang Y and Shen P: Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site. Mol Clin Oncol 1: 503-506, 2013.
APA
Yu, L., Ge, X., Huang, S., Wang, Y., & Shen, P. (2013). Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site. Molecular and Clinical Oncology, 1, 503-506. https://doi.org/10.3892/mco.2013.79
MLA
Yu, L., Ge, X., Huang, S., Wang, Y., Shen, P."Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site". Molecular and Clinical Oncology 1.3 (2013): 503-506.
Chicago
Yu, L., Ge, X., Huang, S., Wang, Y., Shen, P."Primary squamous cell carcinoma of the esophagus initially presenting as a large retroperitoneal mass: A case diagnosed as cancer of unknown primary site". Molecular and Clinical Oncology 1, no. 3 (2013): 503-506. https://doi.org/10.3892/mco.2013.79
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