Laparoscopic radical gastrectomy versus traditional open surgery in elderly patients with gastric cancer: Benefits and complications

Li,Hongtao; Han,Xiaopeng; Su,Lin; Zhu,Wankun; Xu,Wei; Li,Kun; Zhao,Qingchuan; Yang,Hua; Liu,Hongbin

doi:10.3892/mco.2014.283

July-August 2014 Volume 2 Issue 4

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July-August 2014 Volume 2 Issue 4

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Article

Laparoscopic radical gastrectomy versus traditional open surgery in elderly patients with gastric cancer: Benefits and complications

Authors:
- Hongtao Li
- Xiaopeng Han
- Lin Su
- Wankun Zhu
- Wei Xu
- Kun Li
- Qingchuan Zhao
- Hua Yang
- Hongbin Liu
View Affiliations / Copyright

Affiliations: Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou, Gansu 730050, P.R. China, Department of General Surgery, General Hospital of Lanzhou Military Region, Lanzhou, Gansu 730050, P.R. China, Xijing Hospital of Digestive Disease, The Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China, Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, P.R. China
Pages: 530-534
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Published online on: April 28, 2014

https://doi.org/10.3892/mco.2014.283
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Abstract

This study was conducted to compare the therapeutic effect and complications of laparoscopic radical gastrectomy (LRG) with those of traditional open surgery in elderly patients with gastric cancer (GC). We conducted a retrospective comparison of therapeutic efficacy and complications between elderly patients with GC (defined as those aged ≥70 years) who received laparoscopic gastrectomy and those who underwent gastrectomy by open surgery. A total of 108 patients who either underwent laparoscopic surgery (n=54) or traditional open surgery (n=54) at the General Hospital of Lanzhou Military Region between June, 2008 and March, 2009 were analyzed. Compared to traditional open surgery, LRG exhibited several advantages, such as being less invasive, with less intraoperative blood loss, shorter bedbound time, less intubation time, low frequency of fever, less time to normal diet, shorter hospital stay and a low overall incidence of complications. No significant difference was observed between laparoscopic and open surgery in terms of operative time and number of lymph nodes dissected. The 3‑year cancer recurrence and mortality rates were similar in the two groups. In conclusion, LRG is a safe and effective procedure for the management of GC in elderly patients and was found to be superior to traditional open surgery regarding the short‑term curative effect. therefore, LRG represents a feasible and safe surgical approach for elderly patients with GC.

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1	Jemal A, Bray F, Center MM, et al: Global cancer statistics. CA Cancer J Clin. 61:69–90. 2011. View Article : Google Scholar
2	Bai Y and Li ZS: Endoscopic, clinicopathological features and prognosis of very young patients with gastric cancer. J Gastroenterol Hepatol. 26:1626–1629. 2011. View Article : Google Scholar : PubMed/NCBI
3	Saif MW, Makrilia N, Zalonis A, et al: Gastric cancer in the elderly: an overview. Eur J Surg Oncol. 36:709–717. 2010. View Article : Google Scholar : PubMed/NCBI
4	Kitano S, Iso Y, Moriyama M, et al: Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc. 4:146–148. 1994.
5	Pugliese R, Maggioni D, Sansonna F, et al: Outcomes and survival after laparoscopic gastrectomy for adenocarcinoma. Analysis on 65 patients operated on by conventional or robot-assisted minimal access procedures. Eur J Surg Oncol. 35:281–288. 2009. View Article : Google Scholar
6	Hwang SI, Kim HO, Yoo CH, et al: Laparoscopic-assisted distal gastrectomy versus open distal gastrectomy for advanced gastric cancer. Surg Endosc. 23:1252–1258. 2009. View Article : Google Scholar : PubMed/NCBI
7	Francescutti V, Choy I, Biertho L, et al: Gastrectomy and esophagogastrectomy for proximal and distal gastric lesions: a comparison of open and laparoscopic procedures. Surg Innov. 16:134–139. 2009. View Article : Google Scholar : PubMed/NCBI
8	Munish M, Sharma V, Yarussi KM, et al: The use of practice guidelines by the American Society of Anesthesiologists for the identification of surgical patients at high risk of sleep apnea. Chron Respir Dis. 9:221–230. 2012. View Article : Google Scholar : PubMed/NCBI
9	Uyama I, Sakurai Y, Komori Y, et al: The advances of laparoscopic treatment for gastric cancer. Cancer & Chemotherapy. 34:21–24. 2007.(In Japanese).
10	Ramesh HS, Pope D, Gennari R, et al: Optimising surgical management of elderly cancer patients. World J Surg Oncol. 3:172005. View Article : Google Scholar : PubMed/NCBI
11	Ohgami M, Otani Y, Kumai K, et al: Laparoscopic wedge resection of the stomach for early gastric cancer using a lesion-lifting-method: curative and minimally invasive treatment. Zentralbl Chir. 123:465–468. 1998.(In German).
12	Uyama I, Sugioka A, Fujita J, et al: Purely laparoscopic pylorus-preserving gastrectomy with extraperigastric lymphadenectomy for early gastric cancer: a case and technical report. Surg Laparosc Endosc Percutan Tech. 9:418–422. 1999. View Article : Google Scholar
13	Kitano S, Shiraishi N, Uyama I, et al: A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan. Ann Surg. 245:68–72. 2007. View Article : Google Scholar : PubMed/NCBI
14	Kunisaki C, Makino H, Takagawa R, et al: Efficacy of laparoscopy-assisted distal gastrectomy for gastric cancer in the elderly. Surg Endosc. 23:377–383. 2009. View Article : Google Scholar : PubMed/NCBI
15	Ibanez Aguirre FJ, Azagra JS, Erro Azcarate ML, et al: Laparoscopic gastrectomy for gastric adenocarcinoma. Long-term results. Rev Esp Enferm Dig. 98:491–500. 2006.(In English, Spanish).
16	Azagra JS, Ibanez-Aguirre JF, Goergen M, et al: Long-term results of laparoscopic extended surgery in advanced gastric cancer: a series of 101 patients. Hepatogastroenterology. 53:304–308. 2006.PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Laparoscopic radical gastrectomy versus traditional open surgery in elderly patients with gastric cancer: Benefits and complications

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Abstract

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