The value of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in the detection and characterization of soft tissue metastasis

Qiu,Da-Sheng; Xu,Li-Ying; Shames,Salman

doi:10.3892/mco.2014.312

September-October 2014 Volume 2 Issue 5

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September-October 2014 Volume 2 Issue 5

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Article

The value of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in the detection and characterization of soft tissue metastasis

Authors:
- Da-Sheng Qiu
- Li-Ying Xu
- Salman Shames
View Affiliations / Copyright

Affiliations: Department of PET/CT, Hubei Cancer Hospital, Wuhan 430079, P.R. China, Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, P.R. China
Pages: 761-766
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Published online on: June 12, 2014

https://doi.org/10.3892/mco.2014.312
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Abstract

Metastatic tumours presenting as soft tissue metastasis (STM) are relatively rare. STM represents metastasis to the muscle and subcutaneous tissues. The majority of the currently available clinical or radiological data on STM consist of isolated case reports or reviews. The aim of this study was to report the manifestations, origin and distribution of STM detected by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) and to assess the value of 18F-FDG PET/CT in the characterisation of STM. We reviewed 17 cases of patients with STM who underwent 18F-FDG PET̸CT scanning. the imaging and clinical data of these patients were retrospectively analysed. This method is very sensitive in the detection of STM and provides ample information for clinical tumour staging. PET is more sensitive compared to CT in detecting lesions in muscle, before the density and morphology of the soft tissues are altered, providing a clear view within the soft tissue. Due to the limitations in resolution, PET is less sensitive compared to CT in detecting lesions in the subcutaneous tissues. The aim of this study was to improve our knowledge of 18F-FDG PET̸CT findings in the diagnosis of STM and determine its value in the staging of malignant tumours.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

The value of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in the detection and characterization of soft tissue metastasis

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