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Molecular and Clinical Oncology
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Epigenetics

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Article

Specific organ metastases and survival in metastatic non‑small‑cell lung cancer

  • Authors:
    • Tomohiro Tamura
    • Koichi Kurishima
    • Kensuke Nakazawa
    • Katsunori Kagohashi
    • Hiroichi Ishikawa
    • Hiroaki Satoh
    • Nobuyuki Hizawa
  • View Affiliations / Copyright

    Affiliations: Division of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Mito, Ibaraki, Japan, Division of Respiratory Medicine, Tsukuba Medical Center Hospital, Mito, Ibaraki, Japan, Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki, Japan
  • Pages: 217-221
    |
    Published online on: September 4, 2014
       https://doi.org/10.3892/mco.2014.410
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Abstract

the present retrospective study was performed to evaluate the clinicopathological characteristics associated with distant metastasis from non‑small‑cell lung cancer (NSCLC). The records of NSCLC patients with metastasis at the time of diagnosis between 1999 and 2012 were reviewed. Of the consecutive 1,542 NSCLC patients diagnosed during the study period, 729 (47.3%) patients presented with distant metastasis. Among those 729 metastatic NSCLC patients, 250 (34.3%), 234 (32.1%), 207 (28.4%), 122 (16.7%), 98 (13.4%) and 69 (9.5%) had bone, lung, brain, adrenal gland, liver and extrathoracic lymph node metastasis, respectively. In a multivariate analysis using the Cox proportional hazards model, liver and adrenal gland metastases were unfavorable prognostic factors. However, brain and bone metastases were not statistically significant prognostic factors. Using a logistic regression analysis, metastasis to the adrenal glands and the presence of pleural and̸or pericardial fluid effusion were correlated with a poor performance status. Therefore, when planning the treatment of NSCLC patients, particularly those with liver and adrenal gland metastases, we should take into consideration information regarding these unfavorable organ metastases.
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Copy and paste a formatted citation
Spandidos Publications style
Tamura T, Kurishima K, Nakazawa K, Kagohashi K, Ishikawa H, Satoh H and Hizawa N: Specific organ metastases and survival in metastatic non‑small‑cell lung cancer. Mol Clin Oncol 3: 217-221, 2015.
APA
Tamura, T., Kurishima, K., Nakazawa, K., Kagohashi, K., Ishikawa, H., Satoh, H., & Hizawa, N. (2015). Specific organ metastases and survival in metastatic non‑small‑cell lung cancer. Molecular and Clinical Oncology, 3, 217-221. https://doi.org/10.3892/mco.2014.410
MLA
Tamura, T., Kurishima, K., Nakazawa, K., Kagohashi, K., Ishikawa, H., Satoh, H., Hizawa, N."Specific organ metastases and survival in metastatic non‑small‑cell lung cancer". Molecular and Clinical Oncology 3.1 (2015): 217-221.
Chicago
Tamura, T., Kurishima, K., Nakazawa, K., Kagohashi, K., Ishikawa, H., Satoh, H., Hizawa, N."Specific organ metastases and survival in metastatic non‑small‑cell lung cancer". Molecular and Clinical Oncology 3, no. 1 (2015): 217-221. https://doi.org/10.3892/mco.2014.410
Copy and paste a formatted citation
x
Spandidos Publications style
Tamura T, Kurishima K, Nakazawa K, Kagohashi K, Ishikawa H, Satoh H and Hizawa N: Specific organ metastases and survival in metastatic non‑small‑cell lung cancer. Mol Clin Oncol 3: 217-221, 2015.
APA
Tamura, T., Kurishima, K., Nakazawa, K., Kagohashi, K., Ishikawa, H., Satoh, H., & Hizawa, N. (2015). Specific organ metastases and survival in metastatic non‑small‑cell lung cancer. Molecular and Clinical Oncology, 3, 217-221. https://doi.org/10.3892/mco.2014.410
MLA
Tamura, T., Kurishima, K., Nakazawa, K., Kagohashi, K., Ishikawa, H., Satoh, H., Hizawa, N."Specific organ metastases and survival in metastatic non‑small‑cell lung cancer". Molecular and Clinical Oncology 3.1 (2015): 217-221.
Chicago
Tamura, T., Kurishima, K., Nakazawa, K., Kagohashi, K., Ishikawa, H., Satoh, H., Hizawa, N."Specific organ metastases and survival in metastatic non‑small‑cell lung cancer". Molecular and Clinical Oncology 3, no. 1 (2015): 217-221. https://doi.org/10.3892/mco.2014.410
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