Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
May-2015 Volume 3 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2015 Volume 3 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

A prospective clinical trial of radiofrequency ablation for pulmonary metastases

  • Authors:
    • Yizong Wang
    • Xueguan Lu
    • Ying Wang
    • Wentao Li
    • Guodong Li
    • Jun Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, P.R. China, Department of Interventional Radiology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China, Department of Interventional Radiology, Qilu Hospital (Qingdao) of Shandong University, Qingdao, Shandong 266035, P.R. China
  • Pages: 559-562
    |
    Published online on: March 6, 2015
       https://doi.org/10.3892/mco.2015.525
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Pulmonary oligometastases can be treated by local treatment options, such as resection, radiofrequency ablation (RFA), and radiotherapy, in selected patients. In the present study, 67 patients with 115 pulmonary metastases were treated, and all the lesions were treated by RFA and followed with a computed tomography scan. The local control, overall survival (OS), progression‑free survival (PFS) and treatment‑related toxicity were observed. Median follow‑up duration after the initial RFA was 24 months (range, 3‑39 months). The median PFS from RFA was 14 months [95% confidence interval (CI), 11.6‑16.4]. The 6‑, 12‑ and 18‑month PFS rates were 82.1, 55.7 and 27.5%, respectively. The median OS rate from RFA was 24 months (95% CI, 18.2‑29.8). The 1‑, 2‑ and 3‑year OS rates were 83.6, 46.3 and 14.3%, respectively. Primary tumor was significantly correlated to PFS and OS on multivariate analysis, and other variates showed no significance. Therefore, RFA is safe for patient treatment and can be considered as a promising treatment option for patients with pulmonary metastases.
View Figures

Figure 1

Figure 2

View References

1 

Schlijper RC, Grutters JP, Houben R, Dingemans AM, Wildberger JE, Van Raemdonck D, Van Cutsem E, Haustermans K, Lammering G, Lambin P, et al: What to choose as radical local treatment for lung metastases from colo-rectal cancer: Surgery or radiofrequency ablation? Cancer Treat Rev. 40:60–67. 2014. View Article : Google Scholar : PubMed/NCBI

2 

Valls C, Ramos E, Leiva D, Ruiz S, Martinez L and Rafecas A: Safety and efficacy of ultrasound-guided radiofrequency ablation of recurrent colorectal cancer liver metastases after hepatectomy. Scand J Surg. 2014.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI

3 

Hiraki T, Gobara H, Iguchi T, Fujiwara H, Matsui Y and Kanazawa S: Radiofrequency ablation for early-stage nonsmall cell lung cancer. Biomed Res Int. 2014:1520872014. View Article : Google Scholar : PubMed/NCBI

4 

Iguchi T, Hiraki T, Gobara H, Fujiwara H, Matsui Y, Soh J, Toyooka S, Kiura K and Kanazawa S: Percutaneous radiofrequency ablation of lung cancer presenting as ground-glass opacity. Cardiovasc Intervent Radiol. 2014.(Epub ahead of print).

5 

Crabtree T, Puri V, Timmerman R, Fernando H, Bradley J, Decker PA, Paulus R, Putnum JB Jr, Dupuy DE and Meyers B: Treatment of stage I lung cancer in high-risk and inoperable patients: Comparison of prospective clinical trials using stereotactic body radiotherapy (RTOG 0236), sublobar resection (ACOSOG Z4032), and radiofrequency ablation (ACOSOG Z4033). J Thorac Cardiovasc Surg. 145:692–699. 2013. View Article : Google Scholar : PubMed/NCBI

6 

Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, et al: New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer. 45:228–247. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Wang H, Littrup PJ, Duan Y, Zhang Y, Feng H and Nie Z: Thoracic masses treated with percutaneous cryotherapy: Initial experience with more than 200 procedures. Radiology. 235:289–298. 2005. View Article : Google Scholar : PubMed/NCBI

8 

Wolf FJ, Grand DJ, Machan JT, Dipetrillo TA, Mayo-Smith Smith and Dupuy DE: Microwave ablation of lung malignancies: Effectiveness, CT findings, and safety in 50 patients. Radiology. 247:871–879. 2008. View Article : Google Scholar : PubMed/NCBI

9 

Ochiai S, Yamakado K, Kodama H, Nomoto Y, Ii N, Takaki H and Sakuma H: Comparison of therapeutic results from radiofrequency ablation and stereotactic body radiotherapy in solitary lung tumors measuring 5 cm or smaller. Int J Clin Oncol. 2014.(Epub ahead of print). View Article : Google Scholar

10 

Matsui Y, Hiraki T, Gobara H, Fujiwara H, Iguchi T, Shirakawa Y, Fujiwara T, Toyooka S and Kanazawa S: Percutaneous radiofrequency ablation for pulmonary metastases from esophageal cancer: Retrospective evaluation of 21 patients. J Vasc Interv Radiol. 25:1566–1572. 2014. View Article : Google Scholar : PubMed/NCBI

11 

Baba Y, Watanabe M, Yoshida N, Kawanaka K, Yamashita Y and Baba H: Radiofrequency ablation for pulmonary metastases from gastrointestinal cancers. Ann Thorac Cardiovasc Surg. 20:99–105. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Baba Y, Watanabe M, Kawanaka K, Iwagami S, Ishimoto T, Iwatsuki M, Yoshida N, Yamashita Y and Baba H: Radiofrequency ablation for pulmonary metastases from esophageal squamous cell carcinoma. Dis Esophagus. 27:36–41. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Nakamura T, Matsumine A, Yamakado K, Takao M, Uchida A and Sudo A: Clinical significance of radiofrequency ablation and metastasectomy in elderly patients with lung metastases from musculoskeletal sarcomas. J Cancer Res Ther. 9:219–223. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Koelblinger C, Strauss S and Gillams A: Outcome after radiofrequency ablation of sarcoma lung metastases. Cardiovasc Intervent Radiol. 37:147–153. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Petre EN, Jia X, Thornton RH, Sofocleous CT, Alago W, Kemeny NE and Solomon SB: Treatment of pulmonary colorectal metastases by radiofrequency ablation. Clin Colorectal Cancer. 12:37–44. 2013. View Article : Google Scholar : PubMed/NCBI

16 

Hiraki T, Gobara H, Iguchi T, Fujiwara H, Matsui Y and Kanazawa S: Radiofrequency ablation as treatment for pulmonary metastasis of colorectal cancer. World J Gastroenterol. 20:988–996. 2014. View Article : Google Scholar : PubMed/NCBI

17 

Baschnagel AM, Mangona VS, Robertson JM, Welsh RJ, Kestin LL and Grills IS: Lung metastases treated with image-guided stereotactic body radiation therapy. Clin Oncol (R Coll Radiol). 25:236–241. 2013. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Wang Y, Lu X, Wang Y, Li W, Li G and Zhou J: A prospective clinical trial of radiofrequency ablation for pulmonary metastases. Mol Clin Oncol 3: 559-562, 2015.
APA
Wang, Y., Lu, X., Wang, Y., Li, W., Li, G., & Zhou, J. (2015). A prospective clinical trial of radiofrequency ablation for pulmonary metastases. Molecular and Clinical Oncology, 3, 559-562. https://doi.org/10.3892/mco.2015.525
MLA
Wang, Y., Lu, X., Wang, Y., Li, W., Li, G., Zhou, J."A prospective clinical trial of radiofrequency ablation for pulmonary metastases". Molecular and Clinical Oncology 3.3 (2015): 559-562.
Chicago
Wang, Y., Lu, X., Wang, Y., Li, W., Li, G., Zhou, J."A prospective clinical trial of radiofrequency ablation for pulmonary metastases". Molecular and Clinical Oncology 3, no. 3 (2015): 559-562. https://doi.org/10.3892/mco.2015.525
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Y, Lu X, Wang Y, Li W, Li G and Zhou J: A prospective clinical trial of radiofrequency ablation for pulmonary metastases. Mol Clin Oncol 3: 559-562, 2015.
APA
Wang, Y., Lu, X., Wang, Y., Li, W., Li, G., & Zhou, J. (2015). A prospective clinical trial of radiofrequency ablation for pulmonary metastases. Molecular and Clinical Oncology, 3, 559-562. https://doi.org/10.3892/mco.2015.525
MLA
Wang, Y., Lu, X., Wang, Y., Li, W., Li, G., Zhou, J."A prospective clinical trial of radiofrequency ablation for pulmonary metastases". Molecular and Clinical Oncology 3.3 (2015): 559-562.
Chicago
Wang, Y., Lu, X., Wang, Y., Li, W., Li, G., Zhou, J."A prospective clinical trial of radiofrequency ablation for pulmonary metastases". Molecular and Clinical Oncology 3, no. 3 (2015): 559-562. https://doi.org/10.3892/mco.2015.525
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team