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July-2015 Volume 3 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Article

Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer

  • Authors:
    • Yasuhiro Inoue
    • Aya Kawamoto
    • Yoshinaga Okugawa
    • Junichiro Hiro
    • Susumu Saigusa
    • Yuji Toiyama
    • Toshimitsu Araki
    • Koji Tanaka
    • Yasuhiko Mohri
    • Masato Kusunoki
  • View Affiliations / Copyright

    Affiliations: Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Tsu, Mie 514‑8507, Japan
  • Pages: 897-901
    |
    Published online on: March 30, 2015
       https://doi.org/10.3892/mco.2015.530
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Abstract

Colorectal cancer (CRC) is predominantly a disease of the elderly. Elderly patients may also exhibit poorer outcomes due to the increased burden of comorbidities, functional dependency and limited life expectancy. The aim of this study was to evaluate the outcome of laparoscopic surgery in elderly patients with CRC. A total of 148 patients who underwent laparoscopic surgery at our institution between January, 2000 and December, 2011 were enrolled. We compared the differences between elderly patients (aged >75 years, n=48) and non‑elderly patients (aged <75 years, n=100) and evaluated the demographics and disease‑related operative and prognostic data. Postoperative complications occurred in 24 (16.2%) of the 148 patients. The American Society of Anesthesiologists score and comorbidity were found to be significantly correlated with complications and the multivariate analysis demonstrated that pulmonary disease, but not age, was an independent factor affecting postoperative complications (odds ratio = 3.21, 95% confidence interval: 1.02‑10.14, P=0.0470). Patients with pulmonary comorbidities also exhibited similar rates of postoperative complications compared with 259 matched patients who underwent open surgery during same period (41.2 vs. 46.7%, respectively; P=0.7547). In conclusion, chronological age alone should not be considered a contraindication for laparoscopic surgery for CRC in elderly patients. In addition, selection criteria for laparoscopic CRC surgery in elderly as well as non‑elderly patients should include pulmonary comorbidities.
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Copy and paste a formatted citation
Spandidos Publications style
Inoue Y, Kawamoto A, Okugawa Y, Hiro J, Saigusa S, Toiyama Y, Araki T, Tanaka K, Mohri Y, Kusunoki M, Kusunoki M, et al: Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer. Mol Clin Oncol 3: 897-901, 2015.
APA
Inoue, Y., Kawamoto, A., Okugawa, Y., Hiro, J., Saigusa, S., Toiyama, Y. ... Kusunoki, M. (2015). Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer. Molecular and Clinical Oncology, 3, 897-901. https://doi.org/10.3892/mco.2015.530
MLA
Inoue, Y., Kawamoto, A., Okugawa, Y., Hiro, J., Saigusa, S., Toiyama, Y., Araki, T., Tanaka, K., Mohri, Y., Kusunoki, M."Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer". Molecular and Clinical Oncology 3.4 (2015): 897-901.
Chicago
Inoue, Y., Kawamoto, A., Okugawa, Y., Hiro, J., Saigusa, S., Toiyama, Y., Araki, T., Tanaka, K., Mohri, Y., Kusunoki, M."Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer". Molecular and Clinical Oncology 3, no. 4 (2015): 897-901. https://doi.org/10.3892/mco.2015.530
Copy and paste a formatted citation
x
Spandidos Publications style
Inoue Y, Kawamoto A, Okugawa Y, Hiro J, Saigusa S, Toiyama Y, Araki T, Tanaka K, Mohri Y, Kusunoki M, Kusunoki M, et al: Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer. Mol Clin Oncol 3: 897-901, 2015.
APA
Inoue, Y., Kawamoto, A., Okugawa, Y., Hiro, J., Saigusa, S., Toiyama, Y. ... Kusunoki, M. (2015). Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer. Molecular and Clinical Oncology, 3, 897-901. https://doi.org/10.3892/mco.2015.530
MLA
Inoue, Y., Kawamoto, A., Okugawa, Y., Hiro, J., Saigusa, S., Toiyama, Y., Araki, T., Tanaka, K., Mohri, Y., Kusunoki, M."Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer". Molecular and Clinical Oncology 3.4 (2015): 897-901.
Chicago
Inoue, Y., Kawamoto, A., Okugawa, Y., Hiro, J., Saigusa, S., Toiyama, Y., Araki, T., Tanaka, K., Mohri, Y., Kusunoki, M."Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer". Molecular and Clinical Oncology 3, no. 4 (2015): 897-901. https://doi.org/10.3892/mco.2015.530
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