Neutrophil to lymphocyte ratio is an independent prognostic factor in patients with recurrent or metastatic head and neck squamous cell cancer

  • Authors:
    • Derya Kıvrak Salim
    • Hasan Mutlu
    • Melek Karakurt Eryılmaz
    • Ozan Salim
    • Fatma Yalçın Musri
    • Deniz Tural
    • Şeyda Gündüz
    • Hasan Şenol Coşkun
  • View Affiliations

  • Published online on: May 4, 2015     https://doi.org/10.3892/mco.2015.557
  • Pages: 839-842
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The neutrophil to lymphocyte ratio (NLR) has been widely investigated for its prognostic significance in cancer. In the present study, we aimed to determine whether NLR is a prognostic factor in patients with recurrent or metastatic head and neck squamous cell cancer (HNSCC). A total of 79 patients from the Akdeniz University database were retrospectively analyzed. The cut-off NLR was set at 2.93; patients with NLR >2.93 had a median overall survival (OS) of 12.1 months, whereas the median OS was not reached for patients with NLR ≤2.93 (P=0.027). On multivariate analysis, NLR and recurrence or metastatic site were found to be independent prognostic factors for OS (P=0.014 and P=0.002, respectively). Therefore, NLR was identified as an independent prognostic factor for OS in patients with recurrent or metastatic HNSCC.
View Figures
View References

Related Articles

Journal Cover

July-2015
Volume 3 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Salim DK, Mutlu H, Eryılmaz MK, Salim O, Musri FY, Tural D, Gündüz Ş and Coşkun HŞ: Neutrophil to lymphocyte ratio is an independent prognostic factor in patients with recurrent or metastatic head and neck squamous cell cancer. Mol Clin Oncol 3: 839-842, 2015
APA
Salim, D.K., Mutlu, H., Eryılmaz, M.K., Salim, O., Musri, F.Y., Tural, D. ... Coşkun, H.Ş. (2015). Neutrophil to lymphocyte ratio is an independent prognostic factor in patients with recurrent or metastatic head and neck squamous cell cancer. Molecular and Clinical Oncology, 3, 839-842. https://doi.org/10.3892/mco.2015.557
MLA
Salim, D. K., Mutlu, H., Eryılmaz, M. K., Salim, O., Musri, F. Y., Tural, D., Gündüz, Ş., Coşkun, H. Ş."Neutrophil to lymphocyte ratio is an independent prognostic factor in patients with recurrent or metastatic head and neck squamous cell cancer". Molecular and Clinical Oncology 3.4 (2015): 839-842.
Chicago
Salim, D. K., Mutlu, H., Eryılmaz, M. K., Salim, O., Musri, F. Y., Tural, D., Gündüz, Ş., Coşkun, H. Ş."Neutrophil to lymphocyte ratio is an independent prognostic factor in patients with recurrent or metastatic head and neck squamous cell cancer". Molecular and Clinical Oncology 3, no. 4 (2015): 839-842. https://doi.org/10.3892/mco.2015.557