Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
September-2015 Volume 3 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2015 Volume 3 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings

  • Authors:
    • Lie‑Jun Mei
    • Lin‑Wei Wang
    • Chao‑Qun Huang
    • Xiao‑Jun Yang
    • Yan Li
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China
    Copyright: © Mei et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 979-986
    |
    Published online on: June 9, 2015
       https://doi.org/10.3892/mco.2015.573
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

This study was conducted to evaluate the functional impact of peritoneal carcinomatosis (PC) on the gastrointestinal system by oral gastrografin radiography (OGR). OGR was performed on 105 patients with PC from abdominal malignancies. The OGR characteristics were analyzed and compared with intraoperative observations. OGR provided real‑time dynamic information on the functional impacts of PC. The OGR findings were normal in 9 (8.6%) and abnormal in 96 (91.4%) cases. In terms of frequency, 33 cases (31.4%) exhibited mild intestinal aggregation and flattening of the intestinal mucosa; 29 cases (27.6%) exhibited limited intestinal invasion, marginally stenotic small bowel and mucosal deformities; 26 cases (24.8%) exhibited only mild mesenteric contracture and mild slowing of gastrointestinal peristalsis; 5 cases (4.8%) exhibited obvious mesenteric contracture, ball‑like changes, fixed position and disappearance of the intestinal mucosa; 2 cases (1.9%) exhibited complete pyloric obstruction; and 1 case (0.9%) exhibited duodenal obstruction. Gastric PC was associated with a higher percentage of stomach filling defects and small intestinal aggregates compared with PC from other malignancies (P<0.01 for both). In 87 cases, the ORG findings were in accordance with the intraoperative findings (κ=0.726, P<0.001), whereas 17 cases (16.2%) were underestimated and 1 (0.9%) was overestimated by OGR. This study indicated that OGR may be a useful technique for the evaluation of the functional impacts of PC on the gastrointestinal system and may help optimize the selection of patients for treatment.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Koppe MJ, Boerman OC, Oyen WJ and Bleichrodt RP: Peritoneal carcinomatosis of colorectal origin: incidence and current treatment strategies. Ann Surg. 243:212–222. 2006. View Article : Google Scholar : PubMed/NCBI

2 

Huang B, Sun Z, Wang Z, et al: Factors associated with peritoneal metastasis in non-serosa-invasive gastric cancer: a retrospective study of a prospectively-collected database. BMC Cancer. 13:572013. View Article : Google Scholar : PubMed/NCBI

3 

Yang XJ, Li Y and Yonemura Y: Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy to treat gastric cancer with ascites and/or peritoneal carcinomatosis: Results from a Chinese center. J Surg Oncol. 101:457–464. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Yang XJ, Li Y, al-shammaa Hassan AH, et al: Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 cases. Ann Surg Oncol. 16:345–351. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Huang CQ, Feng JP, Yang XJ and Li Y: Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from colorectal cancer: a case-control study from a Chinese center. J Surg Oncol. 109:730–739. 2014. View Article : Google Scholar : PubMed/NCBI

6 

Yang XJ, Huang CQ, Suo T, et al: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trial. Ann Surg Oncol. 18:1575–1581. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Esquivel J, Elias D, Baratti D, Kusamura S and Deraco M: Consensus statement on the loco regional treatment of colorectal cancer with peritoneal dissemination. J Surg Oncol. 98:263–267. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Huang JY, Xu YY, Sun Z, et al: Comparison different methods of intraoperative and intraperitoneal chemotherapy for patients with gastric cancer: a meta-analysis. Asian Pac J Cancer Prev. 13:4379–4385. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Pannu HK, Horton KM and Fishman EK: Thin section dual-phase multidetector-row computed tomography detection of peritoneal metastases in gynecologic cancers. J Comput Assist Tomogr. 27:333–340. 2003. View Article : Google Scholar : PubMed/NCBI

10 

Marin D, Catalano C, Baski M, et al: 64-Section multi-detector row CT in the preoperative diagnosis of peritoneal carcinomatosis: correlation with histopathological findings. Abdom Imaging. 35:694–700. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Franiel T, Diederichs G, Engelken F, Elgeti T, Rost J and Rogalla P: Multi-detector CT in peritoneal carcinomatosis: diagnostic role of thin slices and multiplanar reconstructions. Abdom Imaging. 34:49–54. 2009. View Article : Google Scholar : PubMed/NCBI

12 

de Bree E, Koops W, Kroger R, van Ruth S, Witkamp AJ and Zoetmulder FA: Peritoneal carcinomatosis from colorectal or appendiceal origin: correlation of preoperative CT with intraoperative findings and evaluation of interobserver agreement. J Surg Oncol. 86:64–73. 2004. View Article : Google Scholar : PubMed/NCBI

13 

Coakley FV, Choi PH, Gougoutas CA, et al: Peritoneal metastases: detection with spiral CT in patients with ovarian cancer. Radiology. 223:495–499. 2002. View Article : Google Scholar : PubMed/NCBI

14 

Carmignani CP, Sugarbaker TA, Bromley CM and Sugarbaker PH: Intraperitoneal cancer dissemination: mechanisms of the patterns of spread. Cancer Metastasis Rev. 22:465–472. 2003. View Article : Google Scholar : PubMed/NCBI

15 

Kapoor S, Jain G, Sewkani A, Sharma S, Patel K and Varshney S: Prospective evaluation of oral gastrografin in postoperative small bowel obstruction. J Surg Res. 131:256–260. 2006. View Article : Google Scholar : PubMed/NCBI

16 

Sugarbaker PH: Cytoreductive surgery and peri-operative intraperitoneal chemotherapy as a curative approach to pseudomyxoma peritonei syndrome. Eur J Surg Oncol. 27:239–243. 2001. View Article : Google Scholar : PubMed/NCBI

17 

Roviello F, Caruso S, Neri A and Marrelli D: Treatment and prevention of peritoneal carcinomatosis from gastric cancer by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: overview and rationale. Eur J Surg Oncol. 39:1309–1316. 2013. View Article : Google Scholar : PubMed/NCBI

18 

Yan TD, Morris DL, Shigeki K, Dario B and Marcello D: Preoperative investigations in the management of peritoneal surface malignancy with cytoreductive surgery and perioperative intraperitoneal chemotherapy: Expert consensus statement. J Surg Oncol. 98:224–227. 2008. View Article : Google Scholar : PubMed/NCBI

19 

Liu Y, Endo Y, Fujita T, et al: Cytoreductive surgery under aminolevulinic acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: Results of a phase I trial. Ann Surg Oncol. 21:4256–4262. 2014. View Article : Google Scholar : PubMed/NCBI

20 

Klumpp BD, Aschoff P, Schwenzer N, et al: Peritoneal carcinomatosis: comparison of dynamic contrast-enhanced magnetic resonance imaging with surgical and histopathologic findings. Abdom Imaging. 37:834–842. 2012. View Article : Google Scholar : PubMed/NCBI

21 

Dirisamer A, Schima W, Heinisch M, et al: Detection of histologically proven peritoneal carcinomatosis with fused 18F-FDG-PET/MDCT. Eur J Radiol. 69:536–541. 2009. View Article : Google Scholar : PubMed/NCBI

22 

Funicelli L, Travaini LL, Landoni F, Trifiro G, Bonello L and Bellomi M: Peritoneal carcinomatosis from ovarian cancer: the role of CT and [18F] FDG-PET/CT. Abdom Imaging. 35:701–707. 2010. View Article : Google Scholar : PubMed/NCBI

23 

Bozkurt M, Doganay S, Kantarci M, et al: Comparison of peritoneal tumor imaging using conventional MR imaging and diffusion-weighted MR imaging with different b values. Eur J Radiol. 80:224–228. 2011. View Article : Google Scholar : PubMed/NCBI

24 

Wu Y, Yue X, Shen W, et al: Diagnostic value of diffusion-weighted MR imaging in thyroid disease: application in differentiating benign from malignant disease. BMC Med Imaging. 13:232013. View Article : Google Scholar : PubMed/NCBI

25 

Sanli Y, Turkmen C, Bakir B, et al: Diagnostic value of PET/CT is similar to that of conventional MRI and even better for detecting small peritoneal implants in patients with recurrent ovarian cancer. Nucl Med Commun. 33:509–515. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Kitajima K, Suenaga Y, Ueno Y, et al: Value of fusion of PET and MRI in the detection of intra-pelvic recurrence of gynecological tumor: comparison with 18F-FDG contrast-enhanced PET/CT and pelvic MRI. Ann Nucl Med. 28:25–32. 2014. View Article : Google Scholar : PubMed/NCBI

27 

Khasawneh MA, Ugarte ML, Srvantstian B, Dozois EJ, Bannon MP and Zielinski MD: Role of gastrografin challenge in early postoperative small bowel obstruction. J Gastrointest Surg. 18:363–368. 2014. View Article : Google Scholar : PubMed/NCBI

28 

Ha HK, Kim JS, Lee MS, et al: Differentiation of simple and strangulated small-bowel obstructions: usefulness of known CT criteria. Radiology. 204:507–512. 1997. View Article : Google Scholar : PubMed/NCBI

29 

Fevang BT, Fevang J, Stangeland L, Soreide O, Svanes K and Viste A: Complications and death after surgical treatment of small bowel obstruction: A 35-year institutional experience. Ann Surg. 231:529–537. 2000. View Article : Google Scholar : PubMed/NCBI

30 

Rahmani N, Mohammadpour RA, Khoshnood P, Ahmadi A and Assadpour S: Prospective evaluation of oral gastrografin (R) in the management of postoperative adhesive small bowel obstruction. Indian J Surg. 75:195–199. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Stordahl A, Laerum F, Gjolberg T and Enge I: Water-soluble contrast media in radiography of small bowel obstruction. Comparison of ionic and non-ionic contrast media. Acta Radiol. 29:53–56. 1988. View Article : Google Scholar : PubMed/NCBI

32 

Chen SC, Lin FY, Lee PH, Yu SC, Wang SM and Chang KJ: Water-soluble contrast study predicts the need for early surgery in adhesive small bowel obstruction. Br J Surg. 85:1692–1694. 1998. View Article : Google Scholar : PubMed/NCBI

33 

Assalia A, Schein M, Kopelman D, Hirshberg A and Hashmonai M: Therapeutic effect of oral gastrografin in adhesive, partial small-bowel obstruction: a prospective randomized trial. Surgery. 115:433–437. 1994.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Mei LJ, Wang LW, Huang CQ, Yang XJ and Li Y: Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings. Mol Clin Oncol 3: 979-986, 2015.
APA
Mei, L., Wang, L., Huang, C., Yang, X., & Li, Y. (2015). Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings. Molecular and Clinical Oncology, 3, 979-986. https://doi.org/10.3892/mco.2015.573
MLA
Mei, L., Wang, L., Huang, C., Yang, X., Li, Y."Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings". Molecular and Clinical Oncology 3.5 (2015): 979-986.
Chicago
Mei, L., Wang, L., Huang, C., Yang, X., Li, Y."Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings". Molecular and Clinical Oncology 3, no. 5 (2015): 979-986. https://doi.org/10.3892/mco.2015.573
Copy and paste a formatted citation
x
Spandidos Publications style
Mei LJ, Wang LW, Huang CQ, Yang XJ and Li Y: Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings. Mol Clin Oncol 3: 979-986, 2015.
APA
Mei, L., Wang, L., Huang, C., Yang, X., & Li, Y. (2015). Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings. Molecular and Clinical Oncology, 3, 979-986. https://doi.org/10.3892/mco.2015.573
MLA
Mei, L., Wang, L., Huang, C., Yang, X., Li, Y."Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings". Molecular and Clinical Oncology 3.5 (2015): 979-986.
Chicago
Mei, L., Wang, L., Huang, C., Yang, X., Li, Y."Oral gastrografin radiography for the evaluation of the functional impact of peritoneal carcinomatosis: Correlation with clinicopathological findings". Molecular and Clinical Oncology 3, no. 5 (2015): 979-986. https://doi.org/10.3892/mco.2015.573
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team