1
|
Liu Y, Kao HI and Bambara RA: Flap
endonuclease 1: a central component of DNA metabolism. Annu Rev
Biochem. 73:589–615. 2004. View Article : Google Scholar : PubMed/NCBI
|
2
|
Zheng L, Jia J, David Finger LD, Guo Z, et
al: Functional regulation of FEN1 nuclease and its link to cancer.
Nucleic Acid Res. 39:781–794. 2011. View Article : Google Scholar : PubMed/NCBI
|
3
|
Lieber MR: The FEN-1 family of
structure-specific nucleases in eukaryotic DNA replication,
recombination and repair. Bioessays. 19:233–240. 1997. View Article : Google Scholar : PubMed/NCBI
|
4
|
Tomlinson CG, Atack JM, Chapados B, et al:
Substrate recognition and catalysis by flap endonucleases and
related enzymes. Biochem Soc Trans. 38:433–437. 2010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Harrington JJ and Lieber MR: The
characterization of a mammalian DNA structure-specific
endonuclease. EMBO J. 13:1235–1246. 1994.PubMed/NCBI
|
6
|
Shen B, Singh P, Liu R, et al: Multiple
but dissectible functions of FEN-1 nucleases in nucleic acid
processing, genome stability and diseases. Bioessays. 27:717–729.
2005. View Article : Google Scholar : PubMed/NCBI
|
7
|
Reagan MS, Pittenger C, Siede W and
Friedberg EC: Characterization of a mutant strain of Saccharomyces
cerevisiae with a deletion of the RAD27 gene, a structural homolog
of the RAD2 nucleotide excision repair gene. J Bacteriol.
177:364–371. 1995.PubMed/NCBI
|
8
|
Zheng L, Zhou M, Chai Q, et al: Novel
function of the flap endonuclease 1 complex in processing stalled
DNA replication forks. EMBO Rep. 6:83–89. 2005. View Article : Google Scholar : PubMed/NCBI
|
9
|
Zheng L, Dai H, Qiu J, et al: Disruption
of the FEN-1/PCNA interaction results in DNA replication defects,
pulmonary hypoplasia, pancytopenia and newborn lethality in mice.
Mol Cell Biol. 27:3176–3186. 2007. View Article : Google Scholar : PubMed/NCBI
|
10
|
Henneke G, FriedrichHeineken E and
Hubscher U: Flap endonuclease 1: a novel tumour suppresser protein.
Trends Biochem Sci. 28:384–390. 2003. View Article : Google Scholar : PubMed/NCBI
|
11
|
Henneke G, Koundrioukoff S and Hubscher U:
Phosphorylation of human Fen1 by cyclin-dependent kinase modulates
its role in replication fork regulation. Oncogene. 22:4301–4313.
2003. View Article : Google Scholar : PubMed/NCBI
|
12
|
Kucherlapati M, Yang K, Kuraguchi M, et
al: Haploinsufficiency of flap endonuclease (Fen1) leads to rapid
tumor progression. Proc Natl Acad Sci. 99:9924–9929. 2002.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Wu Z, Lin Y, Xu H, et al: High risk of
benzo [alpha] pyrene-induced lung cancer in E160D FEN1 mutant mice.
Mutat Res. 731:85–91. 2001. View Article : Google Scholar
|
14
|
Xu H, Zheng L, Dai H, et al:
Chemical-induced cancer incidence and underlying mechanisms in Fen1
mutant mice. Oncogene. 30:1072–1081. 2011. View Article : Google Scholar : PubMed/NCBI
|
15
|
Tishkoff DX, Filosi N, Gaida GM and
Kolodner RD: A novel mutation avoidance mechanism dependent on S.
cerevisiae RAD27 is distinct from DNA mismatch repair. Cell.
88:253–263. 1997. View Article : Google Scholar : PubMed/NCBI
|
16
|
Parrish JZ, Yang CL, Shen BH and Xue D:
CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates
with CPS-6/EndoG to promote apoptotic DNA degradation. EMBO J.
22:3451–3460. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Zheng L, Dai H, Zhou M, et al: Fen1
mutations result in autoimmunity, chronic inflammation and cancers.
Nat Med. 13:812–819. 2007. View
Article : Google Scholar : PubMed/NCBI
|
18
|
Yang M, Guo H, Wu C, et al: Functional
FEN1 polymorphisms are associated with DNA damage levels and lung
cancer risk. Hum Mutat. 30:1320–1328. 2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Dai ZJ, Wang XJ, Kang AJ, et al:
Association between APE1 single nucleotide polymorphism (rs1760944)
and cancer risk: a meta-analysis based on 6,419 cancer cases and
6,781 case-free controls. J Cancer. 5:253–259. 2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Lv Z, Liu W, Li D, et al: Association of
functional FEN1 genetic variants and haplotypes and breast cancer
risk. Gene. 538:42–45. 2014. View Article : Google Scholar : PubMed/NCBI
|
21
|
Chen YD, Zhang X, Qiu XG, et al:
Functional FEN1 genetic variants and haplotypes are associated with
glioma risk. J Neurooncol. 111:145–151. 2013. View Article : Google Scholar : PubMed/NCBI
|
22
|
Liu L, Zhou C, Zhou L, et al: Functional
FEN1 genetic variants contribute to risk of hepatocellular
carcinoma, esophageal cancer, gastric cancer and colorectal cancer.
Carcinogenesis. 33:119–123. 2012. View Article : Google Scholar : PubMed/NCBI
|