|
1
|
Arpin D, Mahé MA, Servois V and Claude L:
Predictive factors for acute radiation pneumonitis. Rev Pneumol
Clin. 65:177–186. 2009.(In French). View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Yamashita H, Nakagawa K, Nakamura N, et
al: Exceptionally high incidence of symptomatic grade 2–5 radiation
pneumonitis after stereotactic radiation therapy for lung tumors.
Radiat Oncol. 2:212007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhang XJ, Sun JG, Sun J, et al: Prediction
of radiation pneumonitis in lung cancer patients: A systematic
review. J Cancer Res Clin Oncol. 138:2103–2116. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Giuliani ME, Lindsay PE, Kwan JY, et al:
Correlation of dosimetric and clinical factors with the development
of esophagitis and radiation pneumonitis in patients with
limited-stage small-cell lung carcinoma. Clin Lung Cancer.
16:216–220. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Dang J, Li G, Zang S, Zhang S and Yao L:
Comparison of risk and predictors for early radiation pneumonitis
in patients with locally advanced non-small cell lung cancer
treated with radiotherapy with or without surgery. Lung Cancer.
86:329–333. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tsujino K, Hashimoto T, Shimada T, et al:
Combined analysis of V20, VS5, pulmonary fibrosis score on baseline
computed tomography and patient age improves prediction of severe
radiation pneumonitis after concurrent chemoradiotherapy for
locally advanced non-small-cell lung cancer. J Thorac Oncol.
9:983–990. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Dang J, Li G, Zang S, Zhang S and Yao L:
Risk and predictors for early radiation pneumonitis in patients
with stage III non-small cell lung cancer treated with concurrent
or sequential chemoradiotherapy. Radiat Oncol. 9:1722014.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Siva S, MacManus M, Kron T, et al: A
pattern of early radiation-induced inflammatory cytokine expression
is associated with lung toxicity in patients with non-small cell
lung cancer. PLoS One. 9:e1095602014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Johnston CJ, Williams JP, Elder A, Hernady
E and Finkelstein JN: Inflammatory cell recruitment following
thoracic irradiation. Exp Lung Res. 30:369–382. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Pappas PJ, You R, Rameshwar P, et al:
Dermal tissue fibrosis in patients with chronic venous
insufficiency is associated with increased transforming growth
factor-beta1 gene expression and protein production. J Vasc Surg.
30:1129–1145. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Qi W, Twigg S, Chen X, et al: Integrated
actions of transforming growth factor-beta1 and connective tissue
growth factor in renal fibrosis. Am J Physiol Renal Physiol.
288:F800–F809. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Oberringer M, Meins C, Bubel M and
Pohlemann T: In vitro wounding: Effects of hypoxia and transforming
growth factor beta1 on proliferation, migration and myofibroblastic
differentiation in an endothelial cell-fibroblast co-culture model.
J Mol Histol. 39:37–47. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Anscher MS, Kong FM, Αndrews K, et al:
Plasma transforming growth factor beta1 as a predictor of radiation
pneumonitis. Int J Radiat Oncol Biol Phys. 41:1029–1035. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Yuan X, Liao Z, Liu Z, et al: Single
nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is
associated with the risk of radiation pneumonitis in patients with
non-small-cell lung cancer treated with definitive radiotherapy. J
Clin Oncol. 27:3370–3378. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wang L and Bi N: TGF-beta1 gene
polymorphisms for anticipating radiation-induced pneumonitis in
non-small-cell lung cancer: Different ethnic association. J Clin
Oncol. 28:e621–e622. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Niu X, Li H, Chen Z, et al: A study of
ethnic differences in TGFβ1 gene polymorphisms and effects on the
risk of radiation pneumonitis in non-small-cell lung cancer. J
Thorac Oncol. 7:1668–1675. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Qin R, Zhou J, Chen C, et al: LIN28 is
involved in glioma carcinogenesis and predicts outcomes of
glioblastoma multiforme patients. PLoS One. 9:e864462014.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhang Y, Zhu L, Wang R, et al: Genetic
variants in let-7/Lin28 modulate the risk of oral cavity cancer in
a Chinese Han population. Sci Rep. 4:74342014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Iliopoulos D, Hirsch HA and Struhl K: An
epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA and
IL6 links inflammation to cell transformation. Cell. 139:693–706.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Mayr F and Heinemann U: Mechanisms of
Lin28-mediated miRNA and mRNA regulation - a structural and
functional perspective. Int J Mol Sci. 14:16532–16553. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Oh JS, Kim JJ, Byun JY and Kim IA:
Lin28-let7 modulates radiosensitivity of human cancer cells with
activation of K-Ras. Int J Radiat Oncol Biol Phys. 76:5–8. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wen J, Liu H, Wang Q, et al: Genetic
variants of the LIN28B gene predict severe radiation pneumonitis in
patients with non-small cell lung cancer treated with definitive
radiation therapy. Eur J Cancer. 50:1706–1716. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hildebrandt MA, Komaki R, Liao Z, et al:
Genetic variants in inflammation-related genes are associated with
radiation-induced toxicity following treatment for non-small cell
lung cancer. PLoS One. 5:e124022010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Pu X, Wang L, Chang JY, et al:
Inflammation-related genetic variants predict toxicity following
definitive radiotherapy for lung cancer. Clin Pharmacol Ther.
96:609–615. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hubenak JR, Zhang Q, Branch CD and
Kronowitz SJ: Mechanisms of injury to normal tissue after
radiotherapy: A review. Plast Reconstr Surg. 133:49e–56e. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hornhardt S, Rößler U, Sauter W, et al:
Genetic factors in individual radiation sensitivity. DNA repair
(Amst). 16:54–65. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Patrono C, Sterpone S, Testa A and Cozzi
R: Polymorphisms in base excision repair genes: Breast cancer risk
and individual radiosensitivity. World J Clin Oncol. 5:874–882.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Shiloh Y: ATM and related protein kinases:
Safeguarding genome integrity. Nat Rev Cancer. 3:155–168. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Su D, Ma S, Liu P, et al: Genetic
polymorphisms and treatment response in advanced non-small cell
lung cancer. Lung Cancer. 56:281–288. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bakkenist CJ and Kastan MB: DNA damage
activates ATM through intermolecular autophosphorylation and dimer
dissociation. Nature. 421:499–506. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Worgul BV, Smilenov L, Brenner DJ, Junk A,
Zhou W and Hall EJ: Atm heterozygous mice are more sensitive to
radiation-induced cataracts than are their wild-type counterparts.
Proc Natl Acad Sci USA. 99:9836–9839. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wang SC, Wu CC, Wei YY, Hong JH and Chiang
CS: Inactivation of ataxia telangiectasia mutated gene can increase
intracellular reactive oxygen species levels and alter
radiation-induced cell death pathways in human glioma cells. Int J
Radiat Biol. 87:432–442. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhang L, Yang M, Bi N, et al: ATM
polymorphisms are associated with risk of radiation-induced
pneumonitis. Int J Radiat Oncol Biol Phys. 77:1360–1368. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Yang M, Zhang L, Bi N, et al: Association
of P53 and ATM polymorphisms with risk of radiation-induced
pneumonitis in lung cancer patients treated with radiotherapy. Int
J Radiat Oncol Biol Phys. 79:1402–1407. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Xiong H, Liao Z, Liu Z, et al: ATM
polymorphisms predict severe radiation pneumonitis in patients with
non-small cell lung cancer treated with definitive radiation
therapy. Int J Radiat Oncol Biol Phys. 85:1066–1073. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Srivastava M and Raghavan SC: DNA
double-strand break repair inhibitors as cancer therapeutics. Chem
Biol. 22:17–29. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yin M, Liao Z, Huang YJ, et al:
Polymorphisms of homologous recombination genes and clinical
outcomes of non-small cell lung cancer patients treated with
definitive radiotherapy. PLoS One. 6:e200552011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Yin M, Liao Z, Liu Z, et al: Genetic
variants of the nonhomologous end joining gene LIG4 and severe
radiation pneumonitis in nonsmall cell lung cancer patients treated
with definitive radiotherapy. Cancer. 118:528–535. 2012.
|
|
39
|
Tell G, Fantini D and Quadrifoglio F:
Understanding different functions of mammalian AP endonuclease
(APE1) as a promising tool for cancer treatment. Cell Mol Life Sci.
67:3589–3608. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Yin M, Liao Z, Liu Z, et al: Functional
polymorphisms of base excision repair genes XRCC1 and APEX1 predict
risk of radiation pneumonitis in patients with non-small cell lung
cancer treated with definitive radiation therapy. Int J Radiat
Oncol Biol Phys. 81:e67–e73. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Li H, Liu G, Xia L, et al: A polymorphism
in the DNA repair domain of APEX1 is associated with the
radiation-induced pneumonitis risk among lung cancer patients after
radiotherapy. Br J Radiol. 87:201400932014. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Taricani L, Shanahan F, Pierce RH, Guzi TJ
and Parry D: Phenotypic enhancement of thymidylate synthetase
pathway inhibitors following ablation of Neil1 DNA
glycosylase/lyase. Cell Cycle. 9:4876–4883. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chen Y, Zhu M, Zhang Z, et al: A NEIL1
single nucleotide polymorphism (rs4462560) predicts the risk of
radiation-induced toxicities in esophageal cancer patients treated
with definitive radiotherapy. Cancer. 119:4205–4211. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Cadet J and Wagner JR: DNA base damage by
reactive oxygen species, oxidizing agents and UV radiation. Cold
Spring Harb Perspect Biol. 5:a0125592013. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Kim YW and Byzova TV: Oxidative stress in
angiogenesis and vascular disease. Blood. 123:625–631. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Mittal M, Siddiqui MR, Tran K, Reddy SP
and Malik AB: Reactive oxygen species in inflammation and tissue
injury. Antioxid Redox Signal. 20:1126–1167. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Stankova J, Lawrance AK and Rozen R:
Methylenetetrahydrofolate reductase (MTHFR): A novel target for
cancer therapy. Curr Pharm Des. 14:1143–1150. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Mak RH, Alexander BM, Asomaning K, et al:
A single-nucleotide polymorphism in the methylene tetrahydrofolate
reductase (MTHFR) gene is associated with risk of radiation
pneumonitis in lung cancer patients treated with thoracic radiation
therapy. Cancer. 118:3654–3665. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Mymrikov EV, Seit-Nebi AS and Gusev NB:
Large potentials of small heat shock proteins. Physiol Rev.
91:1123–1159. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Laskowska E: Small heat shock
proteins-role in apoptosis, cancerogenesis and diseases associated
with protein aggregation. Postepy Biochem. 53:19–26. 2007.(In
Polish). PubMed/NCBI
|
|
51
|
Schmid TE and Multhoff G:
Radiation-induced stress proteins - the role of heat shock proteins
(HSP) in anti-tumor responses. Curr Med Chem. 19:1765–1770. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Arrigo AP, Virot S, Chaufour S, et al:
Hsp27 consolidates intracellular redox homeostasis by upholding
glutathione in its reduced form and by decreasing iron
intracellular levels. Antioxid Redox Signal. 7:414–422. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Pang Q, Wei Q, Xu T, et al: Functional
promoter variant rs2868371 of HSPB1 is associated with risk of
radiation pneumonitis after chemoradiation for non-small cell lung
cancer. Int J Radiat Oncol Biol Phys. 85:1332–1339. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Medinger M and Passweg J: Angiogenesis in
myeloproliferative neoplasms, new markers and future directions.
Memo. 7:206–210. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Mittal K, Ebos J and Rini B: Angiogenesis
and the tumor microenvironment: Vascular endothelial growth factor
and beyond. Semin Oncol. 41:235–251. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Folkman J: Role of angiogenesis in tumor
growth and metastasis. Semin Oncol. 29(Suppl 16): 15–18. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Lum H and Roebuck KA: Oxidant stress and
endothelial cell dysfunction. Am J Physiol Cell Physiol.
280:C719–C741. 2001.PubMed/NCBI
|
|
58
|
Fisher M: Injuries to the vascular
endothelium: Vascular wall and endothelial dysfunction. Rev Neurol
Dis. 5(Suppl 1): S4–S11. 2008.PubMed/NCBI
|
|
59
|
Anbalagan D, Yap G, Yuan Y, et al:
Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly
target NF-κB and angiogenesis in breast cancer cells. PLoS One.
9:e1145072014. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Yin M, Liao Z, Yuan X, et al:
Polymorphisms of the vascular endothelial growth factor gene and
severe radiation pneumonitis in non-small cell lung cancer patients
treated with definitive radiotherapy. Cancer Sci. 103:945–950.
2012.
|
|
61
|
Kelsey CR, Jackson L, Langdon S, et al: A
polymorphism within the promoter of the TGFβ1 gene is associated
with radiation sensitivity using an objective radiologic endpoint.
Int J Radiat Oncol Biol Phys. 82:e247–e255. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
De Ruysscher D, Sharifi H, Defraene G, et
al: Quantification of radiation-induced lung damage with CT scans:
The possible benefit for radiogenomics. Acta Oncol. 52:1405–1410.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Kerns SL, West CM, Andreassen CN, et al:
Radiogenomics: The search for genetic predictors of radiotherapy
response. Future Oncol. 10:2391–2406. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Kerns SL, Ostrer H and Rosenstein BS:
Radiogenomics: Using genetics to identify cancer patients at risk
for development of adverse effects following radiotherapy. Cancer
Discov. 4:155–165. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Burnet NG, Barnett GC, Elliott RM,
Dearnaley DP, Pharoah PD, Dunning AM, West CM and Investigators R:
RAPPER Investigators: RAPPER: The radiogenomics of radiation
toxicity. Clin Oncol (R Coll Radiol). 25:431–434. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
West C, Rosenstein BS, Alsner J, et al:
EQUAL-ESTRO: Establishment of a Radiogenomics Consortium. Int J
Radiat Oncol Biol Phys. 76:1295–1296. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Borchiellini D, Etienne-Grimaldi MC,
Thariat J and Milano G: The impact of pharmacogenetics on radiation
therapy outcome in cancer patients. A focus on DNA damage response
genes. Cancer Treat Rev. 38:737–759. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Barnett GC, Thompson D, Fachal L, et al: A
genome wide association study (GWAS) providing evidence of an
association between common genetic variants and late radiotherapy
toxicity. Radiother Oncol. 111:178–185. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Kerns SL, Stock R, Stone N, et al: A
two-stage genome-wide association study to identify single
nucleotide polymorphisms associated with development of erectile
dysfunction following radiation therapy for prostate cancer. Int J
Radiat Oncol Biol Phys. 85:e21–e28. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Manolio TA: Bringing genome-wide
association findings into clinical use. Nat Rev Genet. 14:549–558.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Tuzun E, Sharp AJ, Bailey JA, et al:
Fine-scale structural variation of the human genome. Nat Genet.
37:727–732. 2005. View
Article : Google Scholar : PubMed/NCBI
|