Increased erythropoietin levels as a biomarker of pancreatic adenocarcinoma: A case report

Khan,Rafay; Nai,Qiang; Zhang,Ping; Luo,Hongxiu; Sen,Shraman; Sidhom,Ibrahim; Mathew,Teena; Islam,Mohammad; Sen,Shuvendu; Yousif,Abdalla

doi:10.3892/mco.2015.667

January-2016 Volume 4 Issue 1

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January-2016 Volume 4 Issue 1

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Case Report

Increased erythropoietin levels as a biomarker of pancreatic adenocarcinoma: A case report

Authors:
- Rafay Khan
- Qiang Nai
- Ping Zhang
- Hongxiu Luo
- Shraman Sen
- Ibrahim Sidhom
- Teena Mathew
- Mohammad Islam
- Shuvendu Sen
- Abdalla Yousif
View Affiliations / Copyright

Affiliations: Department of Internal Medicine, Raritan Bay Medical Center, Perth Amboy, NJ 07733, USA
Pages: 134-136
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Published online on: October 30, 2015

https://doi.org/10.3892/mco.2015.667
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Abstract

Pancreatic cancer is one of the deadliest cancers commonly diagnosed at an advanced stage. Early diagnosis is crucial for the timely and potentially curative treatment of this highly fatal disease. Although screening tests have improved the survival rate in malignancies such as colon, breast, cervical and prostate cancer, there is currently no effective screening method available for the early detection of pancreatic cancer. As the sensitivity and specificity of existing biomarkers, such as carbohydrate antigen 19‑9, for the early detection of pancreatic cancer is low, there is a pressing need for the identification of novel cancer markers. An increase in erythropoietin (EPO) levels has been observed in several cases of pancreatic neoplasms. However, the potential role of EPO as a biomarker of pancreatic cancer or malignant transformation requires further investigation. We herein present a case of increased EPO levels in an adult male patient with stage IV pancreatic cancer.

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