Anaplastic carcinoma of the pancreas arising in an intraductal papillary mucinous neoplasm: A case report

Fujii,Kensuke; Nitta,Toshikatsu; Kawasaki,Hiroshi; Kataoka,Jun; Tominaga,Tomo; Inoue,Yoshihiro; Kadota,Eiji; Ishibashi,Takashi; Uchiyama,Kazuhisa

doi:10.3892/mco.2015.671

January-2016 Volume 4 Issue 1

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January-2016 Volume 4 Issue 1

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Case Report Open Access

Anaplastic carcinoma of the pancreas arising in an intraductal papillary mucinous neoplasm: A case report

Authors:
- Kensuke Fujii
- Toshikatsu Nitta
- Hiroshi Kawasaki
- Jun Kataoka
- Tomo Tominaga
- Yoshihiro Inoue
- Eiji Kadota
- Takashi Ishibashi
- Kazuhisa Uchiyama
View Affiliations / Copyright

Affiliations: Department of Gastroenterological Surgery, Shiroyama Hospital, Habikino, Osaka 583‑0872, Japan, Department of General and Gastroenterological Surgery, Osaka Medical College Hospital, Takatsuki, Osaka 569‑0801, Japan, Division of Pathology, Japan Clinical Laboratories, Inc., Moriguchi, Osaka 570-0033, Japan

Copyright: © Fujii et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 39-42
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Published online on: November 9, 2015

https://doi.org/10.3892/mco.2015.671
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Abstract

We herein report a case of anaplastic carcinoma of the pancreas arising in an intraductal papillary mucinous neoplasm (IPMN). A 68‑year‑old Japanese woman was admitted to our hospital complaining of fatigue. Computed tomography revealed an irregular mass in the pancreatic head, which displayed high‑signal intensity on diffusion‑weighted magnetic resonance imaging. Accordingly, the patient was diagnosed with pancreatic cancer and underwent pancreaticoduodenectomy. The histopathological findings revealed intraductal papillary proliferative changes involving the main and branch ducts of the pancreatic head. based on the immunohistochemistry results, the intraductal lesion was diagnosed as IPMN. The pathological diagnosis for the invasive carcinoma was anaplastic giant‑cell carcinoma of the pancreas (ACP), and the focus of IPMN dedifferentiation to ACP was found to be located at the periphery of the IPMN. At 18 months postoperatively, the patient remains disease‑free.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Anaplastic carcinoma of the pancreas arising in an intraductal papillary mucinous neoplasm: A case report

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