Primary intraosseous squamous cell carcinoma in pre-existing keratocystic odontogenic tumor: A case report and literature review
- Authors:
- Ming‑Ru Bai
- Ting Shen
- Yu Chen
- Ning Geng
View Affiliations
Affiliations: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, P.R. China
- Published online on: November 16, 2015 https://doi.org/10.3892/mco.2015.678
-
Pages:
187-190
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Abstract
Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare type of odontogenic carcinoma that arises within the jaws. PIOSCC has no initial connection with oral mucosa and possibly develops from the residues of the odontogenic epithelium or from an odontogenic cyst or tumor. The diagnosis of PIOSCC can be difficult as it must be differentiated from other odontogenic carcinomas, such as malignant ameloblastoma, from SCCs arising from the overlying oral mucosa, from the primary tumors of the maxillary sinus or nasal mucosa, and from the tumors that have metastasized to the jaws from other primary sites. The present study reported a rare case of a 59‑year‑old male patient with a course of keratocystic odontogenic tumor for 25 years, between 1988 and 2013, which eventually transformed into PIOSCC after at least five recurrences and corresponding treatments. The mandible excision and titanium plate reconstruction was performed. Follow‑up examinations have revealed no sign of recurrence thus far. The present study discussed this case from three aspects of clinical history, radiological examination and pathological features.
View References
|
1
|
Bodner L, Manor E, Shear M and van der
Waal I: Primary intraosseous cell carcinoma arising in an
odontogenic cyst: A clinicopathologic analysis of 116 reported
cases. J Oral Pathol Med. 40:733–738. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Suei Y, Tanimoto K, Taguchi A and Wada T:
Primary intraosseous carcinoma: Review of the literature and
diagnostic criteria. J Oral Maxillofac Surg. 52:580–583. 1994.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Thomas G, Pandey M, Mathew A, Abraham EK,
Francis A, Somanathan T, Iype M, Sebastian P and Nair MK: Primary
intraosseous carcinoma of the jaw: Pooled analysis of world
literature and report of two new cases. Int J Oral Maxillofac Surg.
30:349–355. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Huang JW, Luo HY and Li TJ: Primary
intraosseous squamous cell carcinoma of the jaws: Clinicopathologic
presentation and prognostic factors. Arch Pathol Lab Med.
133:1834–1840. 2009.PubMed/NCBI
|
|
5
|
Loos D: Central epidermoid carcinoma of
the jaw. Dtsch Monatschr Zahnheik. 31:3081913.
|
|
6
|
Lugakingira M, Pytynia K, Kolokythas A and
Miloro M: Primary intraosseous carcinoma of the mandible: Case
report and review of the literature. J Oral Maxillofac Surg.
68:2623–2629. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Choi YJ, Oh SH, Kang JH, Choi HY, Kim GT,
Yu JJ, Choi YS and Hwang EH: Primary intraosseous squamous cell
carcinoma mimicking periapical disease: A case report. Imaging Sci
Dent. 42:265–270. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Sukegawa S, Matsuzaki H, Katase N, Kanno
T, Mandai T, Takahashi Y, Asaumi JI and Furuki Y: Primary
intraosseous squamous cell carcinoma of the maxilla possibly
arising from an infected residual cyst: A case report. Oncol Lett.
9:131–135. 2015.PubMed/NCBI
|
|
9
|
González-Alva P, Tanaka A, Oku Y,
Yoshizawa D, Itoh S, Sakashita H, Ide F, Tajima Y and Kusama K:
Keratocystic odontogenic tumor: A retrospective study of 183 cases.
J Oral Sci. 50:205–212. 2008. View Article : Google Scholar : PubMed/NCBI
|
