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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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March-2016 Volume 4 Issue 3

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Case Report

Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report

  • Authors:
    • Seyed Mehdi Hashemi
    • Seyed Amirhossein Fazeli
    • Fatemeh Arabpour-Dahouei
    • Ali Davarian
    • Reza Golabchifard
  • View Affiliations / Copyright

    Affiliations: Division of Hematology and Medical Oncology, Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan 9816743111, Iran, Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan 9816743111, Iran, Students' Scientific Research Center, Zahedan University of Medical Sciences, Zahedan 9816743111, Iran, Department of Biochemistry and Molecular Biophysics, School of Medicine, Washington University, St. Louis, MO 63130, USA
  • Pages: 450-452
    |
    Published online on: December 21, 2015
       https://doi.org/10.3892/mco.2015.718
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Abstract

We herein report a case of colonic polyposis, colorectal carcinoma and large B-cell lymphoma in a 22-year-old male patient with a previous history of childhood lymphoblastic lymphoma. Eight years after lymphoblastic lymphoma, which presented as mediastinal mass and superior vena cava syndrome, the patient complained of abdominal pain, lower gastrointestinal bleeding and an abdominal mass. The surgical exploration revealed numerous mucosal polyps throughout the large intestine, and multifocal masses in the ascending and transverse colon and the rectosigmoid region. A retroperitoneal mass was also found. The pathological examination revealed >100 tubular adenomatous polyps and a multifocal, well‑differentiated adenocarcinoma, with lymph node involvement and pericolic invasion. Interestingly, the immunohistochemical studies confirmed the malignant undifferentiated retroperitoneal mass as large B‑cell lymphoma. Over a period of ~10 years, the patient had suffered from three different malignancies. To the best of our knowledge, such a combination of sporadic adenomatous colonic polyposis, colorectal carcinoma and two extra‑intestinal non‑Hodgkin lymphomas has not been reported to date. It should be considered that each malignancy increases the risk for other neoplastic diseases and a close follow‑up is crucial for early detection of second malignancies and neoplastic syndromes.
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1 

Half E, Bercovich D and Rozen P: Familial adenomatous polyposis. Orphanet J Rare Dis. 4:222009. View Article : Google Scholar : PubMed/NCBI

2 

Omundsen M and Lam FF: The other colonic polyposis syndromes. ANZ J Surg. 82:675–681. 2012. View Article : Google Scholar : PubMed/NCBI

3 

Groen EJ, Roos A, Muntinghe FL, Enting RH, de Vries J, Kleibeuker JH, Witjes MJ, Links TP and van Beek AP: Extra-intestinal manifestations of familial adenomatous polyposis. Ann Surg Oncol. 15:2439–2450. 2008. View Article : Google Scholar : PubMed/NCBI

4 

Itsukuma T, Ishikawa H, Misawa M, Kai S, Fujimori Y, Nakagawa K, Hirota S, Sugihara A, Terada N and Hara H: Familial adenomatous polyposis complicated by chronic myelogenous leukemia, Response to imatinib mesylate. J Gastroenterol. 42:402–405. 2007. View Article : Google Scholar : PubMed/NCBI

5 

Greenberg MS, Anderson KC, Marchetto DJ and Li FP: Acute myelocytic leukemia in two brothers with polyposis coli and carcinoma of the colon. Ann Intern Med. 95:702–703. 1981. View Article : Google Scholar : PubMed/NCBI

6 

Frizelle FA, Hemmings CT, Whitehead MR and Spigelman AD: Familial adenomatous polyposis and duodenal lymphoma. Dis Colon Rectum. 46:1698–1701. 2003. View Article : Google Scholar : PubMed/NCBI

7 

Fearnhead NS, Britton MP and Bodmer WF: The ABC of APC. Hum Mol Genet. 10:721–733. 2001. View Article : Google Scholar : PubMed/NCBI

8 

Rix E, Bröker HJ, Waldherr R and Ho AD: Non-Hodgkin's lymphoma resembling polyposis coli. Histopathology. Endoscopy. 18:165–167. 1986. View Article : Google Scholar : PubMed/NCBI

9 

Fotiadis C, Tsekouras D, Antonakis P, Sfiniadakis J, Genetzakis M and Zografos GC: Gardner's syndrome, A case report and review of the literature. World J Gastroenterol. 11:5408–5411. 2005. View Article : Google Scholar : PubMed/NCBI

10 

Soravia C, Berk T, McLeod RS and Cohen Z: Desmoid disease in patients with familial adenomatous polyposis. Dis Colon Rectum. 43:363–369. 2000. View Article : Google Scholar : PubMed/NCBI

11 

Murphy H, Taylor W, Ellis A and Sturgess R: An unusual case of Turcot's syndrome associated with ileal adenocarcinoma, intestinal non-Hodgkin's lymphoma and duodenal adenocarcinoma. Histopathology. Fam Cancer. 4:139–143. 2005. View Article : Google Scholar : PubMed/NCBI

12 

Giardiello FM, Offerhaus GJ, Lee DH, Krush AJ, Tersmette AC, Booker SV, Kelley NC and Hamilton SR: Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis. Gut. 34:1394–1396. 1993. View Article : Google Scholar : PubMed/NCBI

13 

Jagelman DG, DeCosse JJ and Bussey HJ: Upper gastrointestinal cancer in familial adenomatous polyposis. Lancet. 1:1149–1151. 1988. View Article : Google Scholar : PubMed/NCBI

14 

Spigelman AD, Williams CB, Talbot IC, Domizio P and Phillips RK: Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet. 2:783–785. 1989. View Article : Google Scholar : PubMed/NCBI

15 

Soravia C, Sugg SL, Berk T, Mitri A, Cheng H, Gallinger S, Cohen Z, Asa SL and Bapat BV: Familial adenomatous polyposis-associated thyroid cancer, A clinical, pathological and molecular genetics study. Am J Pathol. 154:127–135. 1999. View Article : Google Scholar : PubMed/NCBI

16 

Matsuo H, Kato T, Hirai T, Kodera Y, Kito T and Nakamura H: A case of cancerous familial adenomatous polyposis in urinary bladder due to migration of colonic mucosa through rectovesical fistula. Am J Gastroenterol. 95:1352–1354. 2000. View Article : Google Scholar : PubMed/NCBI

17 

Wada M, Miller CW, Yokota J, Lee E, Mizoguchi H and Koeffler HP: Molecular analysis of the adenomatous polyposis coli gene in sarcomas, hematological malignancies and noncolonic, neoplastic tissues. J Mol Med (Berl). 75:139–144. 1997. View Article : Google Scholar : PubMed/NCBI

18 

Kiratli H, Bilgiç S and Ozerdem U: Retinoblastoma with acute lymphoblastic leukemia, polyposis coli and multiple hamartomas. J AAPOS. 2:385–386. 1998. View Article : Google Scholar : PubMed/NCBI

19 

Kaplan J, Cushing B, Chang CH, Poland R, Roscamp J, Perrin E and Bhaya N: Familial T-cell lymphoblastic lymphoma, Association with Von Recklinghausen neurofibromatosis and Gardner syndrome. Am J Hematol. 12:247–250. 1982. View Article : Google Scholar : PubMed/NCBI

20 

Genovese F, Becchina G, Nagar C, Ottoveggio G, Giacalone B, Scaglione G, Varriale E and Tralongo V: Primary diffuse large B-cell lymphoma developing within a rectal tubular adenoma with low-grade dysplasia, A case report. J Med Case Rep. 8:1032014. View Article : Google Scholar : PubMed/NCBI

21 

Song W, He YL, Han FH, Cai SR and Peng JJ: Rectal non-Hodgkin lymphoma with concomitant rectal adenocarcinoma, A case report and literature review. Chin J Gastrointest Surg. 14:617–619. 2011.(In Chinese).

22 

Sasaki S, Hatanaka K, Sahara N, Uekusa T, Hirayama K, Shirahata A and Ishimaru M: Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon, Report of a case. Surg Today. 40:975–981. 2010. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Hashemi SM, Fazeli SA, Arabpour-Dahouei F , Davarian A and Golabchifard R: Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report. Mol Clin Oncol 4: 450-452, 2016.
APA
Hashemi, S.M., Fazeli, S.A., Arabpour-Dahouei, F. ., Davarian, A., & Golabchifard, R. (2016). Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report. Molecular and Clinical Oncology, 4, 450-452. https://doi.org/10.3892/mco.2015.718
MLA
Hashemi, S. M., Fazeli, S. A., Arabpour-Dahouei, F. ., Davarian, A., Golabchifard, R."Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report". Molecular and Clinical Oncology 4.3 (2016): 450-452.
Chicago
Hashemi, S. M., Fazeli, S. A., Arabpour-Dahouei, F. ., Davarian, A., Golabchifard, R."Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report". Molecular and Clinical Oncology 4, no. 3 (2016): 450-452. https://doi.org/10.3892/mco.2015.718
Copy and paste a formatted citation
x
Spandidos Publications style
Hashemi SM, Fazeli SA, Arabpour-Dahouei F , Davarian A and Golabchifard R: Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report. Mol Clin Oncol 4: 450-452, 2016.
APA
Hashemi, S.M., Fazeli, S.A., Arabpour-Dahouei, F. ., Davarian, A., & Golabchifard, R. (2016). Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report. Molecular and Clinical Oncology, 4, 450-452. https://doi.org/10.3892/mco.2015.718
MLA
Hashemi, S. M., Fazeli, S. A., Arabpour-Dahouei, F. ., Davarian, A., Golabchifard, R."Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report". Molecular and Clinical Oncology 4.3 (2016): 450-452.
Chicago
Hashemi, S. M., Fazeli, S. A., Arabpour-Dahouei, F. ., Davarian, A., Golabchifard, R."Sporadic colonic polyposis and adenocarcinoma associated with lymphoblastic and large B-cell lymphoma in a young male patient: A case report". Molecular and Clinical Oncology 4, no. 3 (2016): 450-452. https://doi.org/10.3892/mco.2015.718
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