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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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November-2016 Volume 5 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Case Report Open Access

Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report

  • Authors:
    • Yoko Yamamoto
    • Ken Kodama
    • Tomohiro Maniwa
    • Hiroki Kishima
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, Yao Municipal Hospital, Yao, Osaka 581‑0069, Japan, Department of Surgery, Kishima Hospital Main Division, Yao, Osaka 581‑0853, Japan
    Copyright: © Yamamoto et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 550-552
    |
    Published online on: August 26, 2016
       https://doi.org/10.3892/mco.2016.1006
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Abstract

Thymic carcinoma is a rare type of cancer that is more aggressive and is associated with a poorer prognosis compared with thymoma. No definitive clinical management of this disease has been established to date. This report describes the 20‑year clinical course of a 50‑year‑old male patient who was successfully treated for initially diagnosed stage IVb thymic carcinoma. Thymo‑thymectomy combined with resection of the surrounding organs was performed on December 1995 with curative intent (R0) after neoadjuvant chemoradiotherapy. From June 2008 until present, four pleural and subclavicular lymph node metastases have been treated with chemotherapy, radiotherapy and surgery, followed by low‑dose oral steroid therapy. The patient has remained disease‑free for the last 20 months since the initiation of prednisolone treatment. Thus, multidisciplinary treatment may achieve long‑term survival in patients with stage IVb thymic carcinoma.
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1 

Kondo K and Monden Y: Therapy for thymic epithelial tumors: A clinical study of 1320 patients from Japan. Ann Thorac Surg. 76:878–885. 2003. View Article : Google Scholar : PubMed/NCBI

2 

Suster S and Rosai J: Thymic carcinoma. A clinicopathologic study of 60 cases. Cancer. 67:1025–1032. 1991. View Article : Google Scholar : PubMed/NCBI

3 

Toyokawa G, Taguchi K, Kojo M, Toyozawa R, Inamasu E, Morodomi Y, Shiraishi Y, Takenaka T, Hirai F, Yamaguchi M, et al: Recurrence of thymic neuroendocrine carcinoma 24 year after total excision: A case report. Oncol Lett. 6:147–149. 2013.PubMed/NCBI

4 

Bott MJ, Wang H, Travis W, Riely GJ, Bains M, Downey R, Rusch V and Huang J: Management and outcomes of relapse after treatment of thymoma and thymic carcinoma. Ann Thorac Surg. 92:1984–1992. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Hishida T, Nomura S, Yano M, Asamura H, Yamashita M, Ohde Y, Kondo K, Date H, Okumura M and Nagai K: Japanese Association for Research on the Thymus (JART): Long-term outcome and prognostic factors of surgically treated thymic carcinoma: Results of 306 cases from a Japanese nationwide database study. Eur J Cardiothorac Surg. 49:835–841. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Ebgels EA and Pfeiffer RM: Malignant thymoma in the United states: Demographic patterns in incidence and associations with subsequent malignancies. Int J Cancer. 105:546–551. 2003. View Article : Google Scholar : PubMed/NCBI

7 

Travis WD, Brambilla E, Muller-Hermelink HK and Hariis CC: World health organization classification of tumorsPathology and genetics of tumors of the lung, pleura, thymus and heart. Chapter. 3rd. IARC Press; Lyon: pp. pp145–pp975. 2004

8 

Wright CD, Wain JC, Wong DR, Donahue DM, Gaissert HA, Grillo HC and Mathisen DJ: Predictors of recurrence in thymic tumors: Importance of invasion, world health organization histology and size. J Thorac Cardiovasc Surg. 130:1413–1421. 2005. View Article : Google Scholar : PubMed/NCBI

9 

Ogawa K, Toita T, Uno T, Fuwa N, Kakinohana Y, Kamata M, Koja K, Kinjo T, Adachi G and Murayama S: Treatment and prognosis of thymic carcinoma: A retrospective analysis of 40 cases. Cancer. 94:3115–3119. 2002. View Article : Google Scholar : PubMed/NCBI

10 

Nakamura Y, Kunito H, Kubota K, Sekine I, Shinkai T, Tamura T, Kodama T, Sumi M, Kohno S and Saijo N: Platinum-based chemotherapy with or without thoracic radiation therapy in patients with unresectable thymic carcinoma. Jpn J Clin Oncol. 30:385–388. 2000. View Article : Google Scholar : PubMed/NCBI

11 

Funakoshi Y, Shiono H, Inoue M, Kadota Y, Ohta M, Matsuda H, Okumura M and Eimoto T: Glucocorticoids induce G1 cell cycle arrest in human neoplastic thymic epithelial cells. K Cancer Res Clin Oncol. 131:314–322. 2005. View Article : Google Scholar

12 

Kodama K, Doi S, Higashiyama M, Yokouchi H, Yasuda T and Funai H: Dramatic response of postthymomectomy myasthenia gravis with multiple lung nodules to corticosteroids. Ann Thorac Surg. 64:555–557. 1997. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Yamamoto Y, Kodama K, Maniwa T and Kishima H: Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report. Mol Clin Oncol 5: 550-552, 2016.
APA
Yamamoto, Y., Kodama, K., Maniwa, T., & Kishima, H. (2016). Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report. Molecular and Clinical Oncology, 5, 550-552. https://doi.org/10.3892/mco.2016.1006
MLA
Yamamoto, Y., Kodama, K., Maniwa, T., Kishima, H."Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report". Molecular and Clinical Oncology 5.5 (2016): 550-552.
Chicago
Yamamoto, Y., Kodama, K., Maniwa, T., Kishima, H."Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report". Molecular and Clinical Oncology 5, no. 5 (2016): 550-552. https://doi.org/10.3892/mco.2016.1006
Copy and paste a formatted citation
x
Spandidos Publications style
Yamamoto Y, Kodama K, Maniwa T and Kishima H: Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report. Mol Clin Oncol 5: 550-552, 2016.
APA
Yamamoto, Y., Kodama, K., Maniwa, T., & Kishima, H. (2016). Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report. Molecular and Clinical Oncology, 5, 550-552. https://doi.org/10.3892/mco.2016.1006
MLA
Yamamoto, Y., Kodama, K., Maniwa, T., Kishima, H."Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report". Molecular and Clinical Oncology 5.5 (2016): 550-552.
Chicago
Yamamoto, Y., Kodama, K., Maniwa, T., Kishima, H."Successful treatment of advanced thymic carcinoma with lymph node and pleural metastases: A case report". Molecular and Clinical Oncology 5, no. 5 (2016): 550-552. https://doi.org/10.3892/mco.2016.1006
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