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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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November-2016 Volume 5 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Case Report

Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report

  • Authors:
    • Takeyuki Kurosawa
    • Keishi Sugino
    • Kazutoshi Isobe
    • Yoshinobu Hata
    • Yuri Fukasawa
    • Sakae Homma

  • View Affiliations / Copyright

    Affiliations: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo 143‑8541, Japan, Department of Chest Surgery, Toho University Omori Medical Center, Tokyo 143‑8541, Japan, Department of Pathology, Toho University Omori Medical Center, Tokyo 143‑8541, Japan
  • Pages: 553-556
    |
    Published online on: September 15, 2016
       https://doi.org/10.3892/mco.2016.1019
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Abstract

A 37-year-old female smoker without a history of exposure to asbestos was referred to our hospital with persistent pericardial effusion. Chest computed tomography imaging examination revealed an irregular thickened pericardium with large amounts of pericardial effusion and a small pleural effusion. Fluorodeoxyglucose (FDG) positron emission tomography imaging demonstrated intrapericardial FDG accumulation. Blood tests revealed an increase in serum mesothelin levels. Examination of a surgically resected specimen revealed a grayish‑white thickening of the pericardium, with a straw‑colored mucinous pericardial effusion. Histopathological examination confirmed the diagnosis of epithelioid malignant mesothelioma. Although the patient's condition temporarily improved, with decreased levels of serum mesothelin during chemotherapy with carboplatin and pemetrexed, she succumbed to cardiac tamponade 18 months after the initial onset of the symptoms. Primary malignant pericardial mesothelioma (PMPM) is an extremely rare and refractory disorder. Thus, an early definitive diagnosis and timely treatment are crucial for the management of PMPM.
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Copy and paste a formatted citation
Spandidos Publications style
Kurosawa T, Sugino K, Isobe K, Hata Y, Fukasawa Y and Homma S: Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. Mol Clin Oncol 5: 553-556, 2016.
APA
Kurosawa, T., Sugino, K., Isobe, K., Hata, Y., Fukasawa, Y., & Homma, S. (2016). Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. Molecular and Clinical Oncology, 5, 553-556. https://doi.org/10.3892/mco.2016.1019
MLA
Kurosawa, T., Sugino, K., Isobe, K., Hata, Y., Fukasawa, Y., Homma, S."Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report". Molecular and Clinical Oncology 5.5 (2016): 553-556.
Chicago
Kurosawa, T., Sugino, K., Isobe, K., Hata, Y., Fukasawa, Y., Homma, S."Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report". Molecular and Clinical Oncology 5, no. 5 (2016): 553-556. https://doi.org/10.3892/mco.2016.1019
Copy and paste a formatted citation
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Spandidos Publications style
Kurosawa T, Sugino K, Isobe K, Hata Y, Fukasawa Y and Homma S: Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. Mol Clin Oncol 5: 553-556, 2016.
APA
Kurosawa, T., Sugino, K., Isobe, K., Hata, Y., Fukasawa, Y., & Homma, S. (2016). Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. Molecular and Clinical Oncology, 5, 553-556. https://doi.org/10.3892/mco.2016.1019
MLA
Kurosawa, T., Sugino, K., Isobe, K., Hata, Y., Fukasawa, Y., Homma, S."Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report". Molecular and Clinical Oncology 5.5 (2016): 553-556.
Chicago
Kurosawa, T., Sugino, K., Isobe, K., Hata, Y., Fukasawa, Y., Homma, S."Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report". Molecular and Clinical Oncology 5, no. 5 (2016): 553-556. https://doi.org/10.3892/mco.2016.1019
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