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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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December-2016 Volume 5 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Review

Clinical presentation and management of uveal melanoma (Review)

  • Authors:
    • Abelardo Rodríguez
    • Alfonso Dueñas-Gonzalez
    • Sarai Delgado-Pelayo
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, Association for the Prevention of Blindness in Mexico I.A.P, Mexico City 04030, Mexico, Institute of Biomedical Research, UNAM/National Cancer Institute, Mexico City 14080, Mexico
  • Pages: 675-677
    |
    Published online on: September 27, 2016
       https://doi.org/10.3892/mco.2016.1037
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Abstract

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. The majority of the patients are Caucasian (97.8%) and aged 50-80 years. Choroidal melanoma is the predominant type (86.3%). The clinical presentation may range from no symptoms over various types of visual disturbances to visual loss. Examination includes slit-lamp biomicroscopy, indirect ophthalmoscopy and diagnostic testing, such as B‑scan ultrasonography. A number of patients with posterior UM are treated with plaque radiation therapy or enucleation. At present, targeted therapy includes inhibitors of the mitogen-activated protein kinase/mitogen-activated protein kinase kinase signaling pathway. UM disseminates hematogenously, with a high propensity for metastasis to the liver, which the most common site (93% of the cases). While UM is uncommon, a significant proportion of affected patients succumb to this disease and new treatment options to improve patient survival are required.
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Copy and paste a formatted citation
Spandidos Publications style
Rodríguez A, Dueñas-Gonzalez A and Delgado-Pelayo S: Clinical presentation and management of uveal melanoma (Review). Mol Clin Oncol 5: 675-677, 2016.
APA
Rodríguez, A., Dueñas-Gonzalez, A., & Delgado-Pelayo, S. (2016). Clinical presentation and management of uveal melanoma (Review). Molecular and Clinical Oncology, 5, 675-677. https://doi.org/10.3892/mco.2016.1037
MLA
Rodríguez, A., Dueñas-Gonzalez, A., Delgado-Pelayo, S."Clinical presentation and management of uveal melanoma (Review)". Molecular and Clinical Oncology 5.6 (2016): 675-677.
Chicago
Rodríguez, A., Dueñas-Gonzalez, A., Delgado-Pelayo, S."Clinical presentation and management of uveal melanoma (Review)". Molecular and Clinical Oncology 5, no. 6 (2016): 675-677. https://doi.org/10.3892/mco.2016.1037
Copy and paste a formatted citation
x
Spandidos Publications style
Rodríguez A, Dueñas-Gonzalez A and Delgado-Pelayo S: Clinical presentation and management of uveal melanoma (Review). Mol Clin Oncol 5: 675-677, 2016.
APA
Rodríguez, A., Dueñas-Gonzalez, A., & Delgado-Pelayo, S. (2016). Clinical presentation and management of uveal melanoma (Review). Molecular and Clinical Oncology, 5, 675-677. https://doi.org/10.3892/mco.2016.1037
MLA
Rodríguez, A., Dueñas-Gonzalez, A., Delgado-Pelayo, S."Clinical presentation and management of uveal melanoma (Review)". Molecular and Clinical Oncology 5.6 (2016): 675-677.
Chicago
Rodríguez, A., Dueñas-Gonzalez, A., Delgado-Pelayo, S."Clinical presentation and management of uveal melanoma (Review)". Molecular and Clinical Oncology 5, no. 6 (2016): 675-677. https://doi.org/10.3892/mco.2016.1037
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