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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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December-2016 Volume 5 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Case Report

Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report

  • Authors:
    • Chien‑Hsiang Weng
    • Ren‑Ching Wang
    • Cheng‑Chung Wu
    • Tseng‑Hsi Lin
  • View Affiliations / Copyright

    Affiliations: NH Dartmouth Family Medicine Residency, Concord Hospital, Concord, NH 03301, USA, Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung 40705, P.R. China, Division of General Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung 40705, P.R. China, Division of Hematology/Oncology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, P.R. China
  • Pages: 783-785
    |
    Published online on: October 5, 2016
       https://doi.org/10.3892/mco.2016.1044
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Abstract

Gastric cancer is one of the leading causes of cancer‑related mortality worldwide. The majority of gastric cancers are diagnosed at an advanced or metastatic stage, with a 5‑year survival rate of ~5‑20% and a median overall survival of <1 year. Synchronous occurrence of gastric adenocarcinoma and lymphoma is rare, and thus far there is no consensus regarding their management. We herein describe a case of synchronous gastric adenocarcinoma and diffuse large B‑cell lymphoma in a patient with chronic hepatitis B and the treatment strategy. A literature review with the most up‑to‑date treatment options and their application in similar situations was also performed.
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1 

Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, et al: Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet. 376:687–697. 2010. View Article : Google Scholar : PubMed/NCBI

2 

Kim SS, Ruiz VE, Carroll JD and Moss SF: Helicobacter pylori in the pathogenesis of gastric cancer and gastric lymphoma. Cancer Lett. 305:228–238. 2011. View Article : Google Scholar : PubMed/NCBI

3 

Correa P and Piazuelo MB: Helicobacter pylori infection and gastric adenocarcinoma. US Gastroenterol Hepatol Rev. 7:59–64. 2011.PubMed/NCBI

4 

Testerman TL and Morris J: Beyond the stomach: An updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment. World J Gastroenterol. 20:12781–12808. 2014. View Article : Google Scholar : PubMed/NCBI

5 

Mbulaiteye SM, Hisada M and El-Omar EM: Helicobacter pylori associated global gastric cancer burden. Front Biosci (Landmark Ed). 14:1490–1504. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Herrera V and Parsonnet J: Helicobacter pylori and gastric adenocarcinoma. Clin Microbiol Infect. 15:971–976. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Brawner KM, Morrow CD and Smith PD: Gastric microbiome and gastric cancer. Cancer J. 20:211–216. 2014. View Article : Google Scholar : PubMed/NCBI

8 

Atherton JC, Cao P, Peek RM Jr, Tummuru MK, Blaser MJ and Cover TL: Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem. 270:17771–17777. 1995. View Article : Google Scholar : PubMed/NCBI

9 

Ziel KA, Campbell CC, Wilson GL and Gillespie MN: Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene. FASEB J. 18:986–988. 2004.PubMed/NCBI

10 

Harris PR, Smythies LE, Smith PD and Perez-Perez GI: Role of childhood infection in the sequelae of H. pylori disease. Gut Microbes. 4:426–438. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Lee WP, Tai DI, Lan KH, Li AF, Hsu HC, Lin EJ, Lin YP, Sheu ML, Li CP, Chang FY, et al: The −251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. Clin Cancer Res. 11:6431–6441. 2005. View Article : Google Scholar : PubMed/NCBI

12 

Shikata K, Kiyohara Y, Kubo M, Yonemoto K, Ninomiya T, Shirota T, Tanizaki Y, Doi Y, Tanaka K, Oishi Y, et al: A prospective study of dietary salt intake and gastric cancer incidence in a defined Japanese population: The Hisayama study. Int J Cancer. 119:196–201. 2006. View Article : Google Scholar : PubMed/NCBI

13 

Correa P, Fontham ET, Bravo JC, Bravo LE, Ruiz B, Zarama G, Realpe JL, Malcom GT, Li D, Johnson WD and Mera R: Chemoprevention of gastric dysplasia: Randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy. J Natl Cancer Inst. 92:1881–1888. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Chan AO, Chu KM, Yuen ST, Leung SY, Lam SK and Wong J: Synchronous gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma in association with Helicobacter pylori infection: Comparing reported cases between the East and West. Am J Gastroenterol. 96:1922–1924. 2001. View Article : Google Scholar : PubMed/NCBI

15 

de Sanjose S, Dickie A, Alvaro T, Romagosa V, Villanueva M Garcia, Domingo-Domenech E, de Sevilla A Fernandez and El-Omar E: Helicobacter pylori and malignant lymphoma in Spain. Cancer Epidemiol Biomarkers Prev. 13:944–948. 2004.PubMed/NCBI

16 

Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, Orentreich N, Vogelman JH and Friedman GD: Helicobacter pylori infection and gastric lymphoma. N Engl J Med. 330:1267–1271. 1994. View Article : Google Scholar : PubMed/NCBI

17 

Hussell T, Isaacson PG, Crabtree JE, Dogan A and Spencer J: Immunoglobulin specificity of low grade B cell gastrointestinal lymphoma of mucosa-associated lymphoid tissue (MALT) type. Am J Pathol. 142:285–292. 1993.PubMed/NCBI

18 

Wotherspoon AC, Doglioni C, Diss TC, Pan L, Moschini A, de Boni M and Isaacson PG: Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet. 342:575–577. 1993. View Article : Google Scholar : PubMed/NCBI

19 

Cavanna L, Pagani R, Seghini P, Zangrandi A and Paties C: High grade B-cell gastric lymphoma with complete pathologic remission after eradication of Helicobacter pylori infection: Report of a case and review of the literature. World J Surg Oncol. 6:352008. View Article : Google Scholar : PubMed/NCBI

20 

Liu H, Ye H, Ruskone-Fourmestraux A, De Jong D, Pileri S, Thiede C, Lavergne A, Boot H, Caletti G, Wündisch T, et al: T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology. 122:1286–1294. 2002. View Article : Google Scholar : PubMed/NCBI

21 

Fukayama M and Ushiku T: Epstein-Barr virus-associated gastric carcinoma. Pathol Res Pract. 207:529–537. 2011. View Article : Google Scholar : PubMed/NCBI

22 

Park S, Lee J, Ko YH, Han A, Jun HJ, Lee SC, Hwang IG, Park YH, Ahn JS, Jung CW, et al: The impact of Epstein-Barr virus status on clinical outcome in diffuse large B-cell lymphoma. Blood. 110:972–978. 2007. View Article : Google Scholar : PubMed/NCBI

23 

Engels EA, Cho ER and Jee SH: Hepatitis B virus infection and risk of non-Hodgkin lymphoma in South Korea: A cohort study. Lancet Oncol. 11:827–834. 2010. View Article : Google Scholar : PubMed/NCBI

24 

Yood M Ulcickas, Quesenberry CP Jr, Guo D, Caldwell C, Wells K, Shan J, Sanders L, Skovron ML, Iloeje U and Manos MM: Incidence of non-Hodgkin's lymphoma among individuals with chronic hepatitis B virus infection. Hepatology. 46:107–112. 2007. View Article : Google Scholar : PubMed/NCBI

25 

NCCN, . National Comprehensive Cancer Network Guidelines for gastric cancer. Version 3. 2016.https://www.nccn.org/professionals/physician_gls/f_guidelines.aspAccessed September 12, 2016.

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Copy and paste a formatted citation
Spandidos Publications style
Weng CH, Wang RC, Wu CC and Lin TH: Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report. Mol Clin Oncol 5: 783-785, 2016.
APA
Weng, C., Wang, R., Wu, C., & Lin, T. (2016). Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report. Molecular and Clinical Oncology, 5, 783-785. https://doi.org/10.3892/mco.2016.1044
MLA
Weng, C., Wang, R., Wu, C., Lin, T."Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report". Molecular and Clinical Oncology 5.6 (2016): 783-785.
Chicago
Weng, C., Wang, R., Wu, C., Lin, T."Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report". Molecular and Clinical Oncology 5, no. 6 (2016): 783-785. https://doi.org/10.3892/mco.2016.1044
Copy and paste a formatted citation
x
Spandidos Publications style
Weng CH, Wang RC, Wu CC and Lin TH: Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report. Mol Clin Oncol 5: 783-785, 2016.
APA
Weng, C., Wang, R., Wu, C., & Lin, T. (2016). Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report. Molecular and Clinical Oncology, 5, 783-785. https://doi.org/10.3892/mco.2016.1044
MLA
Weng, C., Wang, R., Wu, C., Lin, T."Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report". Molecular and Clinical Oncology 5.6 (2016): 783-785.
Chicago
Weng, C., Wang, R., Wu, C., Lin, T."Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report". Molecular and Clinical Oncology 5, no. 6 (2016): 783-785. https://doi.org/10.3892/mco.2016.1044
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