Hepatocellular carcinoma with inferior vena caval and right atrial tumor thrombi and massive pulmonary artery embolism: A case report

Huang,Jian; Pan,Ze‑Ya; Li,Li; Jiang,Bei‑Ge; Gu,Fang‑Ming; Wang,Zhen‑Guang; Wang,Zhi‑Hong; Zhou,Wei‑Ping

doi:10.3892/mco.2016.1093

January-2017 Volume 6 Issue 1

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January-2017 Volume 6 Issue 1

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Case Report

Hepatocellular carcinoma with inferior vena caval and right atrial tumor thrombi and massive pulmonary artery embolism: A case report

Authors:
- Jian Huang
- Ze‑Ya Pan
- Li Li
- Bei‑Ge Jiang
- Fang‑Ming Gu
- Zhen‑Guang Wang
- Zhi‑Hong Wang
- Wei‑Ping Zhou
View Affiliations / Copyright

Affiliations: Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, P.R. China, Department of Cardiology, The First Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, Jiangxi 330000, P.R. China
Pages: 111-114
|
Published online on: November 24, 2016

https://doi.org/10.3892/mco.2016.1093
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Abstract

The aim of the present study was to report the case of a 55-year-old female patient with a sizeable (7.1x6.2 cm) hepatocellular carcinoma (HCC), who succumbed to massive pulmonary artery embolism. The main symptoms included sudden thoracodynia, dyspnea and transient coma. The initial diagnosis was HCC according to the typical abdominal ultrasound and triple‑phase abdominal computed tomography (CT) findings, chronic hepatitis B infection and elevated α‑fetoprotein levels (1,036 µg/l; normal, 0‑20 µg/l). Two days following admission, the patient developed recurrent chest pain and shortness of breath. The electrocardiogram and myocardial enzyme levels were normal, but the D‑dimer level was elevated to 7,210 µg/l (normal, 0‑550 µg/l). Magnetic resonance angiography and a contrast‑enhanced chest CT confirmed that the inferior vena cava and right atrium were invaded by tumor thrombi; the bilateral pulmonary embolism was also suspected to be formed by tumor thrombi. The final diagnosis was HCC with inferior vena caval and right atrial tumor thrombi, as well as massive pulmonary embolism. Anticoagulation therapy with low‑molecular weight heparin calcium was administered; however, the patient succumbed to pulmonary embolism in <2 months.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Hepatocellular carcinoma with inferior vena caval and right atrial tumor thrombi and massive pulmonary artery embolism: A case report

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