Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
March-2016 Volume 4 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-2016 Volume 4 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients

  • Authors:
    • Li Ma
    • Yueping Liu
    • Jianxin Wang
    • Yuan Chang
    • Long Yu
    • Cuizhi Geng
  • View Affiliations / Copyright

    Affiliations: Breast Disease Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, P.R. China, Department of Pathology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, P.R. China
  • Pages: 456-460
    |
    Published online on: January 7, 2016
       https://doi.org/10.3892/mco.2016.726
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Totally implantable venous access port systems (TIVAPS) are widely used in breast cancer patients. However, complications are frequent and may necessitate device replacement or removal, resulting in additional patient stress and treatment delays. The aim of this study was to investigate possible risk factors for complications. A total of 2,996 consecutive female breast cancer patients, with a median age of 50.2 years (range, 21.2‑85.5 years) were enrolled in this observational, single‑centre study between December, 2008 and April, 2014. TIVAPS implantation was principally performed using local anaesthesia and the blind puncture or Seldinger technique through internal jugular or subclavian vein access. A retrospective chart review was conducted to obtain information associated with TIVAPS and patient data. Insertion performed by blind puncture and Seldinger technique had a success ratio of 96.34 and 99.80%, respectively (χ2=29.905, P<0.001). However, the success ratio of the puncture technique group was 99.76% when the TIVAPS was implanted in the right internal jugular vein. The most common complications were late complications, with an overall incidence rate of 5.41% (162/2,996) during the entire device duration. The most common late complications included fibrin formation (1.84%, 55/2,996), port‑related bacteraemia (1.44%, 43/2,996) and deep vein thrombosis (0.63%, 19/2,996). No patient died during the study. Our results demonstrated that insertion of TIVAPS by blind puncture or the Seldinger technique through internal jugular or subclavian vein access is convenient, and insertion by the Seldinger technique through the right internal jugular vein is the preferred method. Therefore, TIVAPS is safe for continuous infusional chemotherapy regimens for breast cancer patients.
View Figures
View References

1 

Vescia S, Baumgärtner AK, Jacobs VR, Kiechle-Bahat M, Rody A, Loibl S and Harbeck N: Management of venous port systems in oncology: A review of current evidence. Ann Oncol. 19:9–15. 2008. View Article : Google Scholar : PubMed/NCBI

2 

Biffi R, Pozzi S, Agazzi A, Pace U, Floridi A, Cenciarelli S, Peveri V, Cocquio A, Andreoni B and Martinelli G: Use of totally implantable central venous access ports for high-dose chemotherapy and peripheral blood stem cell transplantation: Results of a monocentre series of 376 patients. Ann Oncol. 15:296–300. 2004. View Article : Google Scholar : PubMed/NCBI

3 

Chang YF, Lo AC, Tsai CH, Lee PY, Sun S, Chang TH, Chen CC, Chang YS and Chen JR: Higher complication risk of totally implantable venous access port systems in patients with advanced cancer - a single institution retrospective analysis. Palliat Med. 27:185–191. 2013. View Article : Google Scholar : PubMed/NCBI

4 

Yildizeli B, Laçin T, Batirel HF and Yüksel M: Complications and management of long-term central venous access catheters and ports. J Vasc Access. 5:174–178. 2004.PubMed/NCBI

5 

Biffi R, Orsi F, Pozzi S, Pace U, Bonomo G, Monfardini L, Della Vigna P, Rotmensz N, Radice D, Zampino MG, et al: Best choice of central venous insertion site for the prevention of catheter-related complications in adult patients who need cancer therapy: A randomized trial. Ann Oncol. 20:935–940. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Hartkamp A, van Boxtel AJ, Zonnenberg BA and Witteveen PO: Totally implantable venous access devices: Evaluation of complications and a prospective comparative study of two different port systems. Neth J Med. 57:215–223. 2000. View Article : Google Scholar : PubMed/NCBI

7 

Paleczny J, Banyś-Jafernik B, Gazurek K, Kierpieć K, Szczerba H and Zipser P: Long-term totally implantable venous access port systems - one center experience. Anaesthesiol Intensive Ther. 45:215–222. 2013. View Article : Google Scholar : PubMed/NCBI

8 

Hung M-C, Chen C-J, Wu K-G, Hung GY, Lin YJ and Tang RB: Subcutaneously implanted central venous access device infection in pediatric patients with cancer. J Microbiol Immunol Infect. 42:166–171. 2009.PubMed/NCBI

9 

Narducci F, Jean-Laurent M, Boulanger L, El Bédoui S, Mallet Y, Houpeau JL, Hamdani A, Penel N and Fournier C: Totally implantable venous access port systems and risk factors for complications: A one-year prospective study in a cancer centre. Eur J Surg Oncol. 37:913–918. 2011. View Article : Google Scholar : PubMed/NCBI

10 

Hsieh C-C, Weng H-H, Huang W-S, Wang WK, Kao C-L, Lu MS and Wang CS: Analysis of risk factors for central venous port failure in cancer patients. World J Gastroenterol. 15:4709–4714. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Li J, Fan YY, Xin MZ, Yan J, Hu W, Huang WH, Lin XL and Qin HY: A randomised, controlled trial comparing the long-term effects of peripherally inserted central catheter placement in chemotherapy patients using B-mode ultrasound with modified Seldinger technique versus blind puncture. Eur J Oncol Nurs. 18:94–103. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Lipitz-Snyderman A, Sepkowitz KA, Elkin EB, Pinheiro LC, Sima CS, Son CH, Atoria CL and Bach PB: Long-term central venous catheter use and risk of infection in older adults with cancer. J Clin Oncol. 32:2351–2356. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Linnemann B: Management of complications related to central venous catheters in cancer patients: An update. Semin Thromb Hemost. 40:382–394. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Minassian VA, Sood AK, Lowe P, Sorosky JI, Al-Jurf AS and Buller RE: Longterm central venous access in gynecologic cancer patients. J Am Coll Surg. 191:403–409. 2000. View Article : Google Scholar : PubMed/NCBI

15 

Gallieni M, Pittiruti M and Biffi R: Vascular access in oncology patients. CA Cancer J Clin. 58:323–346. 2008. View Article : Google Scholar : PubMed/NCBI

16 

Del Molin A, Rasero L, Guerretta L, Perfetti E and Clerico M: The late complications of totally implantable central venous access ports: The results from an Italian multicenter prospective observation study. Eur J Oncol Nurs. 15:377–381. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Biffi R, de Braud F, Orsi F, Pozzi S, Mauri S, Goldhirsch A, Nolè F and Andreoni B: Totally implantable central venous access ports for long-term chemotherapy. A prospective study analyzing complications and costs of 333 devices with a minimum follow-up of 180 days. Ann Oncol. 9:767–773. 1998. View Article : Google Scholar : PubMed/NCBI

18 

Pittiruti M, Hamilton H, Biffi R, MacFie J and Pertkiewicz M: ESPEN ESPEN Guidelines on Parenteral Nutrition: Central venous catheters (access, care, diagnosis and therapy of complications). Clin Nutr. 28:365–377. 2009. View Article : Google Scholar : PubMed/NCBI

19 

Beckers MM, Ruven HJ, Seldenrijk CA, Prins MH and Biesma DH: Risk of thrombosis and infections of central venous catheters and totally implanted access ports in patients treated for cancer. Thromb Res. 125:318–321. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Mermel LA: Prevention of intravascular catheter-related infections. Ann Intern Med. 132:391–402. 2000. View Article : Google Scholar : PubMed/NCBI

21 

Groeger JS, Lucas AB, Thaler HT, Friedlander-Klar H, Brown AE, Kiehn TE and Armstrong D: Infectious morbidity associated with long-term use of venous access devices in patients with cancer. Ann Intern Med. 119:1168–1174. 1993. View Article : Google Scholar : PubMed/NCBI

22 

Villain-Guillot P, Gualtieri M, Bastide L and Leonetti JP: In vitro activities of different inhibitors of bacterial transcription against Staphylococcus epidermidis biofilm. Antimicrob Agents Chemother. 51:3117–3121. 2007. View Article : Google Scholar : PubMed/NCBI

23 

Cooper GL, Schiller AL and Hopkins CC: Possible role of capillary action in pathogenesis of experimental catheter-associated dermal tunnel infections. J Clin Microbiol. 26:8–12. 1988.PubMed/NCBI

24 

Raad I, Hachem R, Hanna H, Bahna P, Chatzinikolaou I, Fang X, Jiang Y, Chemaly RF and Rolston K: Sources and outcome of bloodstream infections in cancer patients: The role of central venous catheters. Eur J Clin Microbiol Infect Dis. 26:549–556. 2007. View Article : Google Scholar : PubMed/NCBI

25 

Veenstra DL, Saint S and Sullivan SD: Cost-effectiveness of antiseptic-impregnated central venous catheters for the prevention of catheter-related bloodstream infection. JAMA. 282:554–560. 1999. View Article : Google Scholar : PubMed/NCBI

26 

Lee AY, Levine MN, Butler G, Webb C, Costantini L, Gu C and Julian JA: Incidence, risk factors, and outcomes of catheter-related thrombosis in adult patients with cancer. J Clin Oncol. 24:1404–1408. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Tesselaar ME, Ouwerkerk J, Nooy MA, Rosendaal FR and Osanto S: Risk factors for catheter-related thrombosis in cancer patients. Eur J Cancer. 40:2253–2259. 2004. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Ma L, Liu Y, Wang J, Chang Y, Yu L and Geng C: Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients. Mol Clin Oncol 4: 456-460, 2016.
APA
Ma, L., Liu, Y., Wang, J., Chang, Y., Yu, L., & Geng, C. (2016). Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients. Molecular and Clinical Oncology, 4, 456-460. https://doi.org/10.3892/mco.2016.726
MLA
Ma, L., Liu, Y., Wang, J., Chang, Y., Yu, L., Geng, C."Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients". Molecular and Clinical Oncology 4.3 (2016): 456-460.
Chicago
Ma, L., Liu, Y., Wang, J., Chang, Y., Yu, L., Geng, C."Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients". Molecular and Clinical Oncology 4, no. 3 (2016): 456-460. https://doi.org/10.3892/mco.2016.726
Copy and paste a formatted citation
x
Spandidos Publications style
Ma L, Liu Y, Wang J, Chang Y, Yu L and Geng C: Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients. Mol Clin Oncol 4: 456-460, 2016.
APA
Ma, L., Liu, Y., Wang, J., Chang, Y., Yu, L., & Geng, C. (2016). Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients. Molecular and Clinical Oncology, 4, 456-460. https://doi.org/10.3892/mco.2016.726
MLA
Ma, L., Liu, Y., Wang, J., Chang, Y., Yu, L., Geng, C."Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients". Molecular and Clinical Oncology 4.3 (2016): 456-460.
Chicago
Ma, L., Liu, Y., Wang, J., Chang, Y., Yu, L., Geng, C."Totally implantable venous access port systems and associated complications: A single-institution retrospective analysis of 2,996 breast cancer patients". Molecular and Clinical Oncology 4, no. 3 (2016): 456-460. https://doi.org/10.3892/mco.2016.726
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team