Primary sarcomatoid carcinoma of the jejunum with massive intra-abdominal hemorrhage: A case report and review of the literature

Zhang,Bin; Cheng,Bo; Wang,Linxiong; Zhao,Ke; Zhuo,Guang‑Zuan; Ding,Jian‑Hua

doi:10.3892/mco.2016.809

Primary sarcomatoid carcinoma of the jejunum with massive intra-abdominal hemorrhage: A case report and review of the literature

Authors:
- Bin Zhang
- Bo Cheng
- Linxiong Wang
- Ke Zhao
- Guang‑Zuan Zhuo
- Jian‑Hua Ding
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Affiliations: Department of Colorectal Surgery, The General Hospital of the PLA Rocket Force, Beijing 100088, P.R. China, Department of Clinical Pathology, The General Hospital of the PLA Rocket Force, Beijing 100088, P.R. China, Cancer Center Lab, Chinese People's Liberation Army General Hospital & Beijing Key Laboratory of Cell Engineering & Antibody, Beijing 100853, P.R. China
Published online on: March 9, 2016 https://doi.org/10.3892/mco.2016.809
Pages: 811-816

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Abstract

Primary sarcomatoid carcinoma of the jejunum is an extremely rare condition, with only 16 cases reported in the literature to date. We herein report an additional case of a giant sarcomatoid carcinoma of the jejunum in a 62-year-old male patient, presenting as massive intra-abdominal hemorrhage. During emergency laparotomy, ~5 litres of bloody ascites was found in the peritoneal cavity and the tumor was located in the proximal jejunum. The tumor involved the entire wall of the jejunum and had directly invaded the neighboring parietal peritoneum, omentum, transverse colon and mesentery, with metastatic lymph nodes. The patient underwent palliative resection of the tumor; however, the course was rapidly progressive and he succumbed to progression of abdominal and liver metastases 4 weeks after surgery. The tumor was found to be positive for epithelial and mesenchymal markers on immunohistochemical analysis. This case emphasizes the aggressive clinical course and metastatic nature of this malignant tumor, with a supplementary review of the previously published literature.

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