Sialoblastoma of the cheek: A case report and review of the literature
Corrigendum in: /10.3892/mco.2016.1060
- Authors:
- Published online on: March 30, 2016 https://doi.org/10.3892/mco.2016.840
- Pages: 925-928
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Copyright: © Sitthichaiyakul et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Abstract
Sialoblastoma is a rare salivary gland tumor that recapitulates the primitive salivary gland anlage. The authors herein report a case of sialoblastoma of a minor salivary gland, clinically presenting with progressive enlargement of a mass in the cheek of a 1‑year‑old female infant. Histopathologically, the mass consisted of tight clusters of basaloid cells and partially formed ductal and pseudo‑ductal spaces separated by thin fibrous bands. Immunohistchemical studies demonstrated the presence of cytokeratin AE1̸AE3, p63, CD99, α‑fetoprotein (AFP) and Hep Par‑1 expression in a considerable number of tumor cells. The clinical and pathological characteristics are presented and relevant literature is reviewed. Early complete surgical excision is recommended for the treatment of sialoblastoma. Radiation may be considered in cases with incomplete resection of the tumor. Chemotherapy may play a vital role in extensive, metastatic, or relapsed cases, or in cases with inadequate excision. The follow‑up treatment should be frequent and prolonged. To the best of our knowledge, this is the first reported case of sialoblastoma of the cheek with immunoreactivity for AFP and Hep Par‑1, which may be associated with the embryonic origin of the tumor. AFP may be a useful marker of tumor response in patient with sialoblastoma.
