Esophageal metastasis secondary to extranodal nasal-type natural killer/T-cell lymphoma: A case report

Mo,Zheng‑Ying; Wang,Ping; Yang,Hong‑Wei; Li,Wen-Bin; Liang,Qing‑Le

doi:10.3892/mco.2016.861

July-2016 Volume 5 Issue 1

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July-2016 Volume 5 Issue 1

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Case Report

Esophageal metastasis secondary to extranodal nasal-type natural killer/T-cell lymphoma: A case report

Authors:
- Zheng‑Ying Mo
- Ping Wang
- Hong‑Wei Yang
- Wen-Bin Li
- Qing‑Le Liang
View Affiliations / Copyright

Affiliations: Department of Oncology, Tai-He Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China, Department of Radiology, Ren-Ming Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China, Department of Clinical Laboratory, Tai‑He Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China
Pages: 207-209
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Published online on: April 20, 2016

https://doi.org/10.3892/mco.2016.861
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Abstract

We herein report a case of recurrent nasal natural killer (NK)/T-cell lymphoma in a 21‑year‑old male patient. The patient presented with an esophageal mass, fever and difficulty in swallowing. There were no other obvious sites of recurrence apart from the esophageal lesion. Metastatic esophageal lesions are extremely rare. The histological analysis demonstrated a highly aggressive tumor with a characteristic angiodestructive growth pattern and nasal cavity necrosis. The lymphoma cells were immunopositive for leukocyte common antigen, T-cell intracytoplasmic antigen 1 and CD68, negative for CD56 and CD3, and positive for Epstein‑Barr virus. A computed tomography scan revealed mild thickening of the wall of the lower esophagus. The barium swallow revealed stiffness of the esophageal wall, with limited expansion and mucosal damage. The final diagnosis was primary nasal NK/T‑cell lymphoma, with metastasis to the esophagus. Clinically, it is important to distinguish nasal‑type NK/T‑cell lymphoma from other types of tumors, as its prognosis and treatment of secondary metastases differ significantly.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Esophageal metastasis secondary to extranodal nasal-type natural killer/T-cell lymphoma: A case report

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