Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
July-2016 Volume 5 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July-2016 Volume 5 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report

  • Authors:
    • Li‑Qun Dong
    • Xiao‑Mei Sun
    • Cheng‑Fa Xiang
    • Jin Wu
    • Ping Yu
  • View Affiliations / Copyright

    Affiliations: Department of Pediatrics, Sichuan University, Chengdu, Sichuan 610041, P.R. China, National Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 129-131
    |
    Published online on: May 11, 2016
       https://doi.org/10.3892/mco.2016.895
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Hashimoto's thyroiditis with thyroid cancer in childhood is not as common in the adult population. Hashimoto's thyroiditis is an autoimmune disease associated with autoantibodies, and the association between Hashimoto's thyroiditis and papillary carcinoma of the thyroid remains controversial. The present study reported a 15-year-old adolescent girl with the diagnosis of Hashimoto's thyroiditis with thyroid cancer. With the complexity of the clinical manifestations of Hashimoto's thyroiditis, it can be expressed as not only hyperthyroidism or hypothyroidism, but also normal thyroid function. The long-term treatment, and for children with thyroid cancer, early diagnosis is particularly difficult. In the present case, the diagnosis of Hashimoto's thyroiditis is primarily based on clinical manifestations, anti-thyroglobulin antibody and anti-thyroid microsomal antibody. The only diagnostic imaging ultrasound was negative. The present study discussed the possible reason and the identification of this unique case of Hashimoto's thyroiditis with thyroid cancer.
View Figures

Figure 1

Figure 2

View References

1 

Wasniewska M, Vigone MC, Cappa M, Aversa T, Rubino M and De Luca F: Study Group for Thyroid diseases of Italian Society for Pediatric Endocrinology: Acute suppurative thyroiditis in childhood: relative frequency among thyroid inflammatory diseases. J Endocrinol Invest. 30:346–347. 2007. View Article : Google Scholar : PubMed/NCBI

2 

Zak T, Noczyńska A, Wasikowa R, Zaleska-Dorobisz U and Golenko A: Chronic autoimmune thyroid disease in children and adolescents in the years 1999–2004 in Lower Silesia, Poland. Hormones. 4:45–48. 2005. View Article : Google Scholar : PubMed/NCBI

3 

Gopalakrishnan S, Chugh PK, Chhillar M, Ambardar VK, Sahoo M and Sankar R: Goitrous autoimmune thyroiditis in a pediatric population: a longitudinal study. Pediatrics. 122:e670–e674. 2008. View Article : Google Scholar : PubMed/NCBI

4 

Demirbilek H, Kandemir N, Gonc EN, Ozon A and Alikasifoglu A: Assessment of thyroid function during the long course of Hashimoto's thyroiditis in children and adolescents. Clin Endocrinol. 71:451–454. 2009. View Article : Google Scholar

5 

Skarpa V, Kappaousta E, Tertipi A, Anyfandakis K, Vakaki M, Dolianiti M, Fotinou A and Papathanasiou A: Epidemiological characteristics of children with autoimmune thyroid disease. Hormones. 10:207–214. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Özen S, Berk Ö, Şimşek DG and Darcan S: Clinical course of Hashimoto's thyroiditis and effects of levothyroxine therapy on the clinical course of the disease in children and adolescents. J Clin Res Pediatr Endocrinol. 3:192–197. 2011. View Article : Google Scholar : PubMed/NCBI

7 

De Luca F, Santucci S, Corica D, Pitrolo E, Romeo M and Aversa T: Hashimoto's thyroiditis in childhood: presentation modes and evolution over time. Italian Journal of Pediatrics. 39:82013. View Article : Google Scholar : PubMed/NCBI

8 

Guarino V, Castellone MD, Avilla E and Melillo RM: Thyroid cancer and inflammation. Molecular and Cellular Endocrinology. 321:94–102. 2010. View Article : Google Scholar : PubMed/NCBI

9 

Mechler C, Bounacer A, Suarez H, Saint FM, Magois C, Aillet G and Gaulier A: Papillary thyroid carcinoma: 6 cases from 2 families with associated lymphocytic thyroiditis harbouring RET/PTC rearrangements. Br J Cancer. 85:1831–1837. 2001. View Article : Google Scholar : PubMed/NCBI

10 

Repplinger D, Bargren A, Zhang YW, Adler JT, Haymart M and Chen H: Is Hashimoto's thyroiditis a risk factor for papillary thyroid cancer? J Surg Res. 150:49–52. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Yagasaki H, Inukai T, Uno K, Akahane K, Nemoto A, Takahashi K, Sato H, Goi K, Mouri N, Takano K, et al: Development of severe aplastic anemia in a girl with Hashimoto's thyroiditis and papillary thyroid carcinoma. Rinsho Ketsueki. 44:328–333. 2003.(In Japanese). PubMed/NCBI

12 

Fiore E, Rago T, Latrofa F, Provenzale MA, Piaggi P, Delitala A, Scutari M, Basolo F, Di Coscio G, Grasso L, et al: Hashimoto's thyroiditis is associated with papillary thyroid carcinoma: Role of TSH and of treatment with L-thyroxine. Endocr Relat Cancer. 18:429–437. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Burstein DE, Nagi C, Wang BY and Unger P: Immunohistochemical detection of p53 homolog p63 in solid cell nests, papillary thyroid carcinoma and hashimoto's thyroiditis: A stem cell hypothesis of papillary carcinoma oncogenesis. Hum Pathol. 35:465–473. 2004. View Article : Google Scholar : PubMed/NCBI

14 

Kang DY, Kim KH, Kim JM, Kim SH, Kim JY, Baik HW and Kim YS: High prevalence of RET, RAS and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population. Thyroid. 17:1031–1038. 2007. View Article : Google Scholar : PubMed/NCBI

15 

Haberal AN, Toru S, Ozen O, Arat Z and Bilezikçi B: Diagnostic pitfalls in the evaluation of fine needle aspiration cytology of the thyroid: Correlation with histopathology in 260 cases. Cytopathology. 20:103–108. 2009. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Dong LQ, Sun XM, Xiang CF, Wu J and Yu P: Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report. Mol Clin Oncol 5: 129-131, 2016.
APA
Dong, L., Sun, X., Xiang, C., Wu, J., & Yu, P. (2016). Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report. Molecular and Clinical Oncology, 5, 129-131. https://doi.org/10.3892/mco.2016.895
MLA
Dong, L., Sun, X., Xiang, C., Wu, J., Yu, P."Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report". Molecular and Clinical Oncology 5.1 (2016): 129-131.
Chicago
Dong, L., Sun, X., Xiang, C., Wu, J., Yu, P."Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report". Molecular and Clinical Oncology 5, no. 1 (2016): 129-131. https://doi.org/10.3892/mco.2016.895
Copy and paste a formatted citation
x
Spandidos Publications style
Dong LQ, Sun XM, Xiang CF, Wu J and Yu P: Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report. Mol Clin Oncol 5: 129-131, 2016.
APA
Dong, L., Sun, X., Xiang, C., Wu, J., & Yu, P. (2016). Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report. Molecular and Clinical Oncology, 5, 129-131. https://doi.org/10.3892/mco.2016.895
MLA
Dong, L., Sun, X., Xiang, C., Wu, J., Yu, P."Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report". Molecular and Clinical Oncology 5.1 (2016): 129-131.
Chicago
Dong, L., Sun, X., Xiang, C., Wu, J., Yu, P."Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report". Molecular and Clinical Oncology 5, no. 1 (2016): 129-131. https://doi.org/10.3892/mco.2016.895
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team