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Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis

  • Authors:
    • Xuping Jiang
    • Jiayi Zhang
    • Jingyuan Tang
    • Zhen Xu
    • Wei Zhang
    • Qing Zhang
    • Hongqian Guo
    • Weimin Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Yixing People's Hospital, Yixing, Jiangsu 214200, P.R. China, State Key Laboratory of Reproductive Medicine, Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Department of Urology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China
    Copyright: © Jiang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 301-309
    |
    Published online on: May 20, 2016
       https://doi.org/10.3892/mco.2016.906
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Abstract

The aim of the present study was to determine whether magnetic resonance imaging ‑ ultrasound (MRI‑US) fusion prostate biopsy is superior to systematic biopsy for making a definitive diagnosis of prostate cancer. The two strategies were also compared regarding their ability to detect clinically significant and insignificant prostate cancer. A literature search was conducted through the PubMed, EMBASE and China National Knowledge Infrastructure databases using appropriate search terms. A total of 3,415 cases from 21 studies were included in the present meta‑analysis. Data were expressed as relative risk (RR) and 95% confidence interval. The results revealed that MRI‑US fusion biopsy achieved a higher rate of overall prostate cancer detection compared with systematic biopsy (RR=1.09; P=0.047). Moreover, MRI‑US fusion biopsy detected more clinically significant cancers compared with systematic biopsy (RR=1.22; P<0.01). It is therefore recommended that multi-parametric MRI-US is performed in men suspected of having prostate cancer to optimize the detection of clinically significant disease, while reducing the burden of biopsies.
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Copy and paste a formatted citation
Spandidos Publications style
Jiang X, Zhang J, Tang J, Xu Z, Zhang W, Zhang Q, Guo H and Zhou W: Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis. Mol Clin Oncol 5: 301-309, 2016.
APA
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q. ... Zhou, W. (2016). Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis. Molecular and Clinical Oncology, 5, 301-309. https://doi.org/10.3892/mco.2016.906
MLA
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q., Guo, H., Zhou, W."Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis". Molecular and Clinical Oncology 5.2 (2016): 301-309.
Chicago
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q., Guo, H., Zhou, W."Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis". Molecular and Clinical Oncology 5, no. 2 (2016): 301-309. https://doi.org/10.3892/mco.2016.906
Copy and paste a formatted citation
x
Spandidos Publications style
Jiang X, Zhang J, Tang J, Xu Z, Zhang W, Zhang Q, Guo H and Zhou W: Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis. Mol Clin Oncol 5: 301-309, 2016.
APA
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q. ... Zhou, W. (2016). Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis. Molecular and Clinical Oncology, 5, 301-309. https://doi.org/10.3892/mco.2016.906
MLA
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q., Guo, H., Zhou, W."Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis". Molecular and Clinical Oncology 5.2 (2016): 301-309.
Chicago
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q., Guo, H., Zhou, W."Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis". Molecular and Clinical Oncology 5, no. 2 (2016): 301-309. https://doi.org/10.3892/mco.2016.906
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