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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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August-2016 Volume 5 Issue 2

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

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Case Report

Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review

  • Authors:
    • Huaqiong Huang
    • Shuangli Zhu
    • Shaobin Wang
    • Wen Li
  • View Affiliations / Copyright

    Affiliations: Department of Respiratory Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China
  • Pages: 380-382
    |
    Published online on: June 2, 2016
       https://doi.org/10.3892/mco.2016.916
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Abstract

Brain metastasis (BM) commonly occurs in patients with advanced lung cancer, and is associated with poor prognosis and limited treatment options, particularly for end‑stage patients who are in poor physical and mental state. We herein present a case of lung adenocarcinoma with BM, as revealed by tumor marker and imaging studies. The patient was a 74-year-old woman who was diagnosed with lung adenocarcinoma with several metastatic lesions in the mediastinal lymph nodes, bone and brain. The patient underwent two cycles of chemotherapy, but the cancer recurred with enlarged BM, resulting in confusion and body dysfunction. The patient then received epidermal growth factor receptor‑tyrosine kinase inhibitor (EGFR‑TKI) therapy with icotinib. After approximately 12 h of treatment the symptoms disappeared, and the metastatic lesions in the brain largely regressed in the following months. Our case indicates that the EGFR‑TKI icotinib may provide a rapid and safe approach for emergency situations with BM from lung adenocarcinoma.
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Copy and paste a formatted citation
Spandidos Publications style
Huang H, Zhu S, Wang S and Li W: Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review. Mol Clin Oncol 5: 380-382, 2016.
APA
Huang, H., Zhu, S., Wang, S., & Li, W. (2016). Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review. Molecular and Clinical Oncology, 5, 380-382. https://doi.org/10.3892/mco.2016.916
MLA
Huang, H., Zhu, S., Wang, S., Li, W."Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review". Molecular and Clinical Oncology 5.2 (2016): 380-382.
Chicago
Huang, H., Zhu, S., Wang, S., Li, W."Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review". Molecular and Clinical Oncology 5, no. 2 (2016): 380-382. https://doi.org/10.3892/mco.2016.916
Copy and paste a formatted citation
x
Spandidos Publications style
Huang H, Zhu S, Wang S and Li W: Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review. Mol Clin Oncol 5: 380-382, 2016.
APA
Huang, H., Zhu, S., Wang, S., & Li, W. (2016). Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review. Molecular and Clinical Oncology, 5, 380-382. https://doi.org/10.3892/mco.2016.916
MLA
Huang, H., Zhu, S., Wang, S., Li, W."Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review". Molecular and Clinical Oncology 5.2 (2016): 380-382.
Chicago
Huang, H., Zhu, S., Wang, S., Li, W."Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review". Molecular and Clinical Oncology 5, no. 2 (2016): 380-382. https://doi.org/10.3892/mco.2016.916
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