Hypofractionated stereotactic radiotherapy for dumbbell-shaped hypoglossal schwannomas: Two cases of long-term follow-up and a review of the literature

Li,Yong; Lou,Jinrong; Qiu,Shujun; Guo,Yutian; Pan,Mianshun

doi:10.3892/mco.2016.922

August-2016 Volume 5 Issue 2

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August-2016 Volume 5 Issue 2

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Article

Hypofractionated stereotactic radiotherapy for dumbbell-shaped hypoglossal schwannomas: Two cases of long-term follow-up and a review of the literature

Authors:
- Yong Li
- Jinrong Lou
- Shujun Qiu
- Yutian Guo
- Mianshun Pan
View Affiliations / Copyright

Affiliations: Center of Radiation Oncology, Wujing Hospital, Shanghai 201103, P.R. China, Department of Internal Medicine, Jiading Central Hospital, Shanghai 201800, P.R. China
Pages: 371-374
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Published online on: June 8, 2016

https://doi.org/10.3892/mco.2016.922
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Abstract

Cases of hypoglossal schwannoma are extremely rare. Historically, microsurgical resection has been the standard treatment, but it may not always be feasible; thus, it is crucial to investigate alternative treatments. We herein present the cases of two patients, both of whom presented with tongue deviation and hemiatrophy, accompanied by headaches. Magnetic resonance imaging revealed a dumbbell‑shaped tumor originating from the hypoglossal nerve that was adjacent to the cranial base in each patient. Hypofractionated stereotactic radiotherapy was used to treat the tumors, with a total dose of 30 Gy in 3-Gy fractions delivered to the planning target volume. Several months later, the tumors had significantly decreased in size and the symptoms of the two patients had gradually improved.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Hypofractionated stereotactic radiotherapy for dumbbell-shaped hypoglossal schwannomas: Two cases of long-term follow-up and a review of the literature

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