Renal cell carcinoma presenting as a simple renal cyst: A case report

Yu,Yanlan; Ma,Liang; Wang,Zhenghui; Zhang,Zhigen

doi:10.3892/mco.2017.1173

April-2017 Volume 6 Issue 4

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

April-2017 Volume 6 Issue 4

Full Size Image

Case Report

Renal cell carcinoma presenting as a simple renal cyst: A case report

Authors:
- Yanlan Yu
- Liang Ma
- Zhenghui Wang
- Zhigen Zhang
View Affiliations / Copyright

Affiliations: Department of Urology, Sir Run‑Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China
Pages: 550-552
|
Published online on: February 24, 2017

https://doi.org/10.3892/mco.2017.1173
Expand metrics +

Abstract

Cases of renal cell carcinoma (RCC) presenting as a simple cyst are extremely rare. We herein report the case of a patient with RCC diagnosed as a simple renal cyst preoperatively. A 39-year-old female patient presented with abdominal pain for 3 months. Ultrasonography and contrast‑enhanced computed tomography revealed a simple cyst in the left kidney. The patient underwent laparoscopic decortication of the renal cyst. Biochemical analysis of the cystic fluid revealed unusually low levels of potassium, sodium, calcium and glucose, and the histological examination of the floor of the cyst indicated malignancy. Laparoscopic nephrectomy was performed 20 days later and the pathological examination confirmed the diagnosis of RCC of the clear cell type. At the 2‑year follow‑up, the patient remained well and recurrence‑free on imaging. The aim of the present study was to emphasize the importance of recognizing that RCC may occur in what appears to be a simple renal cyst based on imaging results. Biochemical analysis of the cystic fluid may help identify the presence of malignancy.

View Figures

View References

1	Bosniak MA: The current radiological approach to renal cysts. Radiology. 158:1–10. 1986. View Article : Google Scholar : PubMed/NCBI
2	Israel GM and Bosniak MA: An update of the Bosniak renal cyst classification system. Urology. 66:484–488. 2005. View Article : Google Scholar : PubMed/NCBI
3	Li G, Bilal I, Gentil-Perret A, Feng G, Zhao A, Peoc'h M, Genin C, Tostain J and Gigante M: CA9 as a molecular marker for differential diagnosis of cystic renal tumors. Urol Oncol. 30:463–468. 2012. View Article : Google Scholar : PubMed/NCBI
4	Lin CJ, Chen YC, Chen HH, Wu CJ and Hsu JM: Renal cell carcinoma presenting as a huge simple renal cyst. Med Oncol. 25:104–106. 2008. View Article : Google Scholar : PubMed/NCBI
5	Visapää H, Glucker E, Haukka J, Taari K and Nisen H: Papillary renal cell cancer is strongly associated with simple renal cysts. Urol Int. 91:269–272. 2013. View Article : Google Scholar : PubMed/NCBI
6	Sakai N, Kanda F, Kondo K, Fukuoka H and Tanaka T: Sonographically detected malignant transformation of a simple renal cyst. Int J Urol. 8:23–25. 2001. View Article : Google Scholar : PubMed/NCBI
7	Takao T, Gotoh T, Takada S and Sugao H: Cystic renal cell carcinoma diagnosed as a simple cyst preoperatively with incidental renal tumor: A case report. Hinyokika Kiyo. 45:339–342. 1999.(In Japanese). PubMed/NCBI
8	Omachi T, Sakamoto W, Kishimoto T, Kawano M, Oyama A, Kamizuru M, Maekawa M, Hagihara S and Nakamura K: A case of renal cyst associated with renal cell carcinoma-characteristics of intracystic fluid associated with renal cell carcinoma from Japanese reports. Hinyokika Kiyo. 38:323–326. 1992.(In Japanese). PubMed/NCBI
9	Siegel CL: Accuracy of diagnosis by guided biopsy of renal mass lesions classified indeterminate by imaging studies. J Urol. 165:322–323. 2001. View Article : Google Scholar : PubMed/NCBI
10	Kadekawa K, Miyazato M, Saito S, Morozumi M, Matsuzaki A, Yoshimi N and Sugaya K: Renal cell carcinoma originating in a renal cyst in a 12-year-old girl. J Pediatr Surg. 44:e5–e7. 2009. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Renal cell carcinoma presenting as a simple renal cyst: A case report

This article is mentioned in:

Abstract

Figure 1

Figure 2

Related Articles