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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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May-2017 Volume 6 Issue 5

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Case Report

Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report

  • Authors:
    • Marco Casaccia
    • Simona Macina
    • Rosario Fornaro
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, IRCCS - Azienda Ospedaliera Universitaria San Martino-IST, University of Genoa, Ι-16132 Genoa, Italy
  • Pages: 799-801
    |
    Published online on: April 6, 2017
       https://doi.org/10.3892/mco.2017.1212
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Abstract

Von Hippel-Lindau (VHL) disease is an inherited syndrome with autosomal-dominant transmission, characterized by central nervous system and retinal hemangioblastomas, visceral cysts and tumors. Optimal surgical treatment, including its timing, remains a controversial topic. The present study reports the case of a 67-year-old female patient with adrenal and pancreatic manifestations of VHL. A laparoscopic cortex-sparing left adrenalectomy for a 4-cm pheochromocytoma and pancreatic enucleation for pancreatic polypeptidoma of the pancreas tail were performed during the same operative procedure. The total operative time was 240 min. There were no operative complications, and the surgery was completed laparoscopically with minimal blood loss. A prolonged hospital stay was necessary to treat a grade C postoperative pancreatic fistula. The histopathological result was an adrenal pheochromocytoma and a well-differentiated neuroendocrine tumor, secreting pancreatic polypeptides. In conclusion, organ-sparing laparoscopic surgery is an important option for treating simultaneous lesions in several abdominal solid viscera, such as VHL disease, and the present case study represents, to the best of the authors' knowledge, the first report of single-stage laparoscopic adrenalectomy and pancreatic tumor enucleation.
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Copy and paste a formatted citation
Spandidos Publications style
Casaccia M, Macina S and Fornaro R: Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report. Mol Clin Oncol 6: 799-801, 2017.
APA
Casaccia, M., Macina, S., & Fornaro, R. (2017). Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report. Molecular and Clinical Oncology, 6, 799-801. https://doi.org/10.3892/mco.2017.1212
MLA
Casaccia, M., Macina, S., Fornaro, R."Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report". Molecular and Clinical Oncology 6.5 (2017): 799-801.
Chicago
Casaccia, M., Macina, S., Fornaro, R."Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report". Molecular and Clinical Oncology 6, no. 5 (2017): 799-801. https://doi.org/10.3892/mco.2017.1212
Copy and paste a formatted citation
x
Spandidos Publications style
Casaccia M, Macina S and Fornaro R: Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report. Mol Clin Oncol 6: 799-801, 2017.
APA
Casaccia, M., Macina, S., & Fornaro, R. (2017). Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report. Molecular and Clinical Oncology, 6, 799-801. https://doi.org/10.3892/mco.2017.1212
MLA
Casaccia, M., Macina, S., Fornaro, R."Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report". Molecular and Clinical Oncology 6.5 (2017): 799-801.
Chicago
Casaccia, M., Macina, S., Fornaro, R."Single-stage laparoscopic adrenalectomy for pheochromocytoma and enucleation of a pancreatic neuroendocrine tumor in Von Hippel-Lindau disease: A case report". Molecular and Clinical Oncology 6, no. 5 (2017): 799-801. https://doi.org/10.3892/mco.2017.1212
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