Hepatoid adenocarcinoma of the lung metastasizing to the tonsil

Valle,Luca; Thomas,Joel; Kim,Chul; Szabo,Eva; Brown,G.  Thomas; Citrin,Deborah; Rajan,Arun

doi:10.3892/mco.2017.1215

May-2017 Volume 6 Issue 5

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May-2017 Volume 6 Issue 5

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Article

Hepatoid adenocarcinoma of the lung metastasizing to the tonsil

Authors:
- Luca Valle
- Joel Thomas
- Chul Kim
- Eva Szabo
- G. Thomas Brown
- Deborah Citrin
- Arun Rajan
View Affiliations / Copyright

Affiliations: Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1906, USA, Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1906, USA, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1906, USA
Pages: 705-707
|
Published online on: April 10, 2017

https://doi.org/10.3892/mco.2017.1215
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Abstract

Hepatoid adenocarcinoma (HAC) is a rare tumor that typically originates in gastrointestinal tissue, such as the stomach, but can also occasionally originate in the lung. The majority of HACs express α-fetoprotein (AFP) on tumor cells, and serum AFP can be used as a marker of response to treatment or disease progression. HAC has a poor prognosis, although early diagnosis and aggressive treatment can result in long-term survival. To the best of our knowledge, this is the first reported case of HAC metastasizing to the tonsil. Irradiation using intensity-modulated radiation therapy (IMRT) to 30 Gray (Gy) achieved a significant, and durable tumor response. IMRT can be considered for local control of HAC at other metastatic sites of disease.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Hepatoid adenocarcinoma of the lung metastasizing to the tonsil

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Abstract

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