Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
September-2017 Volume 7 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2017 Volume 7 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report

  • Authors:
    • Hongli Wang
    • Fengtao Liu
    • Ran Gu
    • Yong Li
    • Fengxi Su
  • View Affiliations / Copyright

    Affiliations: Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat‑sen Memorial Hospital, Sun Yat‑sen University, Guangzhou, Guangdong 510120, P.R. China
  • Pages: 473-475
    |
    Published online on: July 13, 2017
       https://doi.org/10.3892/mco.2017.1322
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Adenoid cystic carcinoma (ACC) of the breast is a rare tumor comprising <0.1% of all breast malignancies. The present study reports the case of a 66‑year‑old woman who underwent multiple imaging techniques, including mammography, ultrasonography and magnetic resonance imaging (MRI). The patient reported gradual enlargement of a mass in the left breast. Mammography identified a high‑density, irregular mass, with nipple retraction. Ultrasonography revealed an irregular, complex cystic and solid mass with an unclear margin in the subareolar region. The internal vascularity was seen on Doppler examination. The lesion on MRI was also mixed cystic and solid, with an irregular shape and irregular margins. The solid part of the lesion appeared heterogeneously isointense on T1‑weighted imaging (WI) and a slightly high signal on T2WI, and exhibited internal septations with a low signal on T2WI. Following injection of contrast agent, the enhancement of the solid part was rapid and heterogeneous. The cystic parts of lesion appeared as high‑signal on T1WI and T2WI. The tumor infiltrated the left nipple and adjacent skin. The patient underwent a left modified radical mastectomy with axillary lymph node dissection. The pathological examination confirmed the tumor as ACC of the left breast. The axillary lymph nodes were negative for tumor metastasis. Therefore, the differential diagnosis of mixed cystic and solid breast masses with unclear margins and internal septations on T2WI exhibiting delayed enhancement, must include ACC.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Cavanzo FJ and Taylor HB: Adenoid cystic carcinoma of the breast. An analysis of 21 cases. Cancer. 24:740–745. 1969. View Article : Google Scholar : PubMed/NCBI

2 

Cleveland RH, Nice CM Jr and Ziskind J: Primary adenoid cystic carcinoma (cylindroma) of the trachea. Radiology. 122:597–600. 1977. View Article : Google Scholar : PubMed/NCBI

3 

Prempree T, Villasanta U and Tang CK: Management of adenoid cystic carcinoma of the uterine cervix (cylindroma): Report of six cases and reappraisal of all cases reported in the medical literature. Cancer. 46:1631–1635. 1980. View Article : Google Scholar : PubMed/NCBI

4 

Olofsson J and van Nostrand AW: Adenoid cystic carcinoma of the larynx: A report of four cases and a review of the literature. Cancer. 40:1307–1313. 1977. View Article : Google Scholar : PubMed/NCBI

5 

Addison A and Parker RT: Adenoid cystic carcinoma of Bartholin's gland: A review of the literature and report of a patient. Gynecol Oncol. 5:196–201. 1977. View Article : Google Scholar : PubMed/NCBI

6 

Boujelbene N, Khabir A, Boujelbene N, Sozzi W Jeanneret, Mirimanoff RO and Khanfir K: Clinical review-breast adenoid cystic carcinoma. Breast. 21:124–127. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Tang W, Peng WJ, Gu YJ, Zhu H, Jiang TT and Li C: Imaging manifestation of adenoid cystic carcinoma of the breast. J Comput Assist Tomogr. 39:523–530. 2015. View Article : Google Scholar : PubMed/NCBI

8 

Glazebrook KN, Reynolds C, Smith RL, Gimenez EI and Boughey JC: Adenoid cystic carcinoma of the breast. AJR Am J Roentgenol. 194:1391–1396. 2010. View Article : Google Scholar : PubMed/NCBI

9 

Billroth T: Studies on the Development of the Blood Vessels Combined with Observations from the Royal Surgical University Clinic of Berlin. Georg Reimer, Berlin. 55–69. 1856.(In German).

10 

Geschickter CF and Copeland MM: Diseases of the Breast: Diagnosis, Pathology, Treatment. 2nd. J B Lippincott; Philadelphia: pp. 421–422. 1945

11 

Ghabach B, Anderson WF, Curtis RE, Huycke MM, Lavigne JA and Dores GM: Adenoid cystic carcinoma of the breast in the United States (1977 to 2006): A population-based cohort study. Breast Cancer Res. 12:R542010. View Article : Google Scholar : PubMed/NCBI

12 

Da Silva L, Buck L, Simpson PT, Reid L, McCallum N, Madigan BJ and Lakhani SR: Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Arch. 454:107–114. 2009. View Article : Google Scholar : PubMed/NCBI

13 

Arpino G, Clark GM, Mohsin S, Bardou VJ and Elledge RM: Adenoid cystic carcinoma of the breast: Molecular markers, treatment, and clinical outcome. Cancer. 94:2119–2127. 2002. View Article : Google Scholar : PubMed/NCBI

14 

Mastropasqua MG, Maiorano E, Pruneri G, Orvieto E, Mazzarol G, Vento AR and Viale G: Immunoreactivity for c-kit and p63 as an adjunct in the diagnosis of adenoid cystic carcinoma of the breast. Mod Pathol. 18:1277–1282. 2005. View Article : Google Scholar : PubMed/NCBI

15 

Peters GN and Wolff M: Adenoid cystic carcinoma of the breast. Report of 11 new cases: Review of the literature and discussion of biological behavior. Cancer. 52:680–686. 1983. View Article : Google Scholar : PubMed/NCBI

16 

Youk JH, Kim MJ, Kim EK, Lee JY, Oh KK and Park BW: Recurrence of adenoid cystic carcinoma in the breast after lumpectomy and adjuvant therapy. J Ultrasound Med. 25:921–924. 2006. View Article : Google Scholar : PubMed/NCBI

17 

Ichikawa K, Mizukami Y, Takayama T, Takemura A, Miyati T and Taniya T: A case of adenoid cystic carcinoma of the breast. J Med Ultrason (2001). 34:193–196. 2007. View Article : Google Scholar : PubMed/NCBI

18 

de Luis E, Apesteguía L, Noguera JJ, Pina L, Martínez-Regueira F, Miguel C and Sáenz J: Adenoid cystic carcinoma of the breast. Radiologia. 48:235–240. 2006.(In Spanish). View Article : Google Scholar : PubMed/NCBI

19 

Santamaría G, Velasco M, Zanón G, Farrús B, Molina R, Solé M and Fernández PL: Adenoid cystic carcinoma of the breast: Mammographic appearance and pathologic correlation. AJR Am J Roentgenol. 171:1679–1683. 1998. View Article : Google Scholar : PubMed/NCBI

20 

Tsuboi N, Ogawa Y, Inomata T, Nishioka A, Yoshida D, Yoshida S and Moriki T: Dynamic MR appearance of adenoid cystic carcinoma of the breast in a 67-year-old female. Radiat Med. 16:225–228. 1998.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Wang H, Liu F, Gu R, Li Y and Su F: Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report. Mol Clin Oncol 7: 473-475, 2017.
APA
Wang, H., Liu, F., Gu, R., Li, Y., & Su, F. (2017). Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report. Molecular and Clinical Oncology, 7, 473-475. https://doi.org/10.3892/mco.2017.1322
MLA
Wang, H., Liu, F., Gu, R., Li, Y., Su, F."Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report". Molecular and Clinical Oncology 7.3 (2017): 473-475.
Chicago
Wang, H., Liu, F., Gu, R., Li, Y., Su, F."Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report". Molecular and Clinical Oncology 7, no. 3 (2017): 473-475. https://doi.org/10.3892/mco.2017.1322
Copy and paste a formatted citation
x
Spandidos Publications style
Wang H, Liu F, Gu R, Li Y and Su F: Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report. Mol Clin Oncol 7: 473-475, 2017.
APA
Wang, H., Liu, F., Gu, R., Li, Y., & Su, F. (2017). Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report. Molecular and Clinical Oncology, 7, 473-475. https://doi.org/10.3892/mco.2017.1322
MLA
Wang, H., Liu, F., Gu, R., Li, Y., Su, F."Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report". Molecular and Clinical Oncology 7.3 (2017): 473-475.
Chicago
Wang, H., Liu, F., Gu, R., Li, Y., Su, F."Rare imaging appearance of adenoid cystic carcinoma of the breast: A case report". Molecular and Clinical Oncology 7, no. 3 (2017): 473-475. https://doi.org/10.3892/mco.2017.1322
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team