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Article

Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women

  • Authors:
    • Li Zhang
    • Pingping Zhou
    • Zhaowei Meng
    • Lu Gong
    • Chongjie Pang
    • Xue Li
    • Qiang Jia
    • Jian Tan
    • Na Liu
    • Tianpeng Hu
    • Qing Zhang
    • Qiyu Jia
    • Kun Song
  • View Affiliations / Copyright

    Affiliations: Department of Infectious Diseases, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China, Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China, Department of Health Management, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China
  • Pages: 1039-1044
    |
    Published online on: October 2, 2017
       https://doi.org/10.3892/mco.2017.1433
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Abstract

Infectious mononucleosis (IM) due to Epstein‑Barr virus infection is common. Uric acid (UA) is an important endogenous antioxidant. To the best of our knowledge, the association between UA and IM has not been comprehensively investigated to date. The aim of the present study was to investigate this association in Chinese patients. A total of 95 patients (47 men and 48 women) with IM were recruited, along with 95 healthy controls. Clinical data were classified by patient sex. Receiver operating characteristic (ROC) curve analysis was adopted to determine the cut‑off values of UA for IM diagnosis and prediction. Crude and adjusted odds ratios (ORs) of UA for IM were analyzed by binary logistic regression. The UA levels were significantly lower in IM patients compared with those in controls. In addition, UA levels in men were significantly higher compared with those in women. The ROC curve demonstrated good diagnostic and predictive values of UA for IM in both sexes. The UA cut‑off values were 326.00 and 243.50 µmol/l for diagnosing IM in men and women, respectively, with a diagnostic accuracy of 76.596 and 80.208%, respectively. Binary logistic regression analysis revealed a significant risk of IM in the low UA quartiles in both sexes. Following adjustments, the ORs even increased. Women with low UA levels appeared to be more susceptible to IM. For example, the crude ORs in quartile 1 were 24.000 and 52.500 for men and women, respectively, and the respective adjusted ORs were 31.437 and 301.746 (all P<0.01). To the best of our knowledge, the present study is the first to demonstrate the inverse association between UA and IM, suggesting a progressive decrease of antioxidant reserve in IM. Moreover, low UA was suggestive of IM, particularly in women.
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1 

Luzuriaga K and Sullivan JL: Infectious mononucleosis. N Engl J Med. 362:1993–2000. 2010. View Article : Google Scholar : PubMed/NCBI

2 

Vouloumanou EK, Rafailidis PI and Falagas ME: Current diagnosis and management of infectious mononucleosis. Curr Opin Hematol. 19:14–20. 2012. View Article : Google Scholar : PubMed/NCBI

3 

Lennon P, O'Neill JP, Fenton JE and O'Dwyer T: Challenging the use of the lymphocyte to white cell count ratio in the diagnosis of infectious mononucleosis by analysis of a large cohort of monospot test results. Clin Otolaryngol. 35:397–401. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Henle G, Henle W and Diehl V: Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis. Proc Natl Acad Sci USA. 59:pp. 94–101. 1968, View Article : Google Scholar : PubMed/NCBI

5 

Zhang Q, Lou S, Meng Z and Ren X: Gender and age impacts on the correlations between hyperuricemia and metabolic syndrome in Chinese. Clin Rheumatol. 30:777–787. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Zhang J, Meng Z, Zhang Q, Liu L, Song K, Tan J, Li X, Jia Q, Zhang G and He Y: Gender impact on the correlations between subclinical thyroid dysfunction and hyperuricemia in Chinese. Clin Rheumatol. 35:143–149. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Liu L, Lou S, Xu K, Meng Z, Zhang Q and Song K: Relationship between lifestyle choices and hyperuricemia in Chinese men and women. Clin Rheumatol. 32:233–239. 2013. View Article : Google Scholar : PubMed/NCBI

8 

Llull L, Amaro S and Chamorro Á: Administration of uric acid in the emergency treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 16:42016. View Article : Google Scholar : PubMed/NCBI

9 

Wang Z, Lin Y, Liu Y, Chen Y, Wang B, Li C, Yan S, Wang Y and Zhao W: Serum uric acid levels and outcomes after acute ischemic stroke. Mol Neurobiol. 53:1753–1759. 2016. View Article : Google Scholar : PubMed/NCBI

10 

Zhang X, Huang ZC, Lu TS, You SJ, Cao YJ and Liu CF: Prognostic significance of uric acid levels in ischemic stroke patients. Neurotox Res. 29:10–20. 2016. View Article : Google Scholar : PubMed/NCBI

11 

Liu B, Shen Y, Xiao K, Tang Y, Cen L and Wei J: Serum uric acid levels in patients with multiple sclerosis: A meta-analysis. Neurol Res. 34:163–171. 2012.PubMed/NCBI

12 

Moccia M, Lanzillo R, Costabile T, Russo C, Carotenuto A, Sasso G, Postiglione E, De Luca Picione C, Vastola M, Maniscalco GT, et al: Uric acid in relapsing-remitting multiple sclerosis: A 2-year longitudinal study. J Neurol. 262:961–967. 2015. View Article : Google Scholar : PubMed/NCBI

13 

Liu J, Li M, Wang X, Yi H, Xu L, Zhong XF and Peng FH: Serum uric acid levels in patients with infections of central nervous system. Acta Neurol Belg. 116:303–308. 2016. View Article : Google Scholar : PubMed/NCBI

14 

Collazos J, Blanco MS, Guerra E, Mayo J and Martínez E: Sequential evaluation of serum urate concentrations in AIDS patients with infections of the central nervous system. Clin Chem Lab Med. 38:1293–1296. 2000. View Article : Google Scholar : PubMed/NCBI

15 

Morato-Conceicao YT, Alves-Junior ER, Arruda TA, Lopes JC and Fontes CJ: Serum uric acid levels during leprosy reaction episodes. PeerJ. 4:e17992016. View Article : Google Scholar : PubMed/NCBI

16 

Dylewski JS and Gerson M: Hyperuricemia in patients with infectious mononucleosis. Can Med Assoc J. 132:1169–1170. 1985.PubMed/NCBI

17 

Cowdrey SC: Hyperuricemia in infectious mononucleosis. JAMA. 196:319–321. 1966. View Article : Google Scholar : PubMed/NCBI

18 

Cowdrey SC: Hyperuricemia in infectious mononucleosis: Further observations. J Am Coll Health Assoc. 18:382–383. 1970.PubMed/NCBI

19 

Sugita K, Hagisawa S, Satoh Y, Eguchi M and Furukawa T: Recurrent hepatosplenomegaly and peripheral blood cytopenia, persistent epstein-barr virus infection and central nervous system manifestation in a patient with lymphadenopathy and low serum uric acid. Acta Paediatr Jpn. 40:362–366. 1998. View Article : Google Scholar : PubMed/NCBI

20 

Moccia M, Lanzillo R, Palladino R, Russo C, Carotenuto A, Massarelli M, Vacca G, Vacchiano V, Nardone A, Triassi M and Morra VB: Uric acid: A potential biomarker of multiple sclerosis and of its disability. Clin Chem Lab Med. 53:753–759. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Wu XW, Muzny DM, Lee CC and Caskey CT: Two independent mutational events in the loss of urate oxidase during hominoid evolution. J Mol Evol. 34:78–84. 1992. View Article : Google Scholar : PubMed/NCBI

22 

Santos CX, Anjos EI and Augusto O: Uric acid oxidation by peroxynitrite: Multiple reactions, free radical formation and amplification of lipid oxidation. Arch Biochem Biophys. 372:285–294. 1999. View Article : Google Scholar : PubMed/NCBI

23 

Becker BF: Towards the physiological function of uric acid. Free Radic Biol Med. 14:615–631. 1993. View Article : Google Scholar : PubMed/NCBI

24 

Messerli FH, Makani H and Halpern D: Gout. N Engl J Med. 364:1876–1877. 2011. View Article : Google Scholar : PubMed/NCBI

25 

Neogi T: Clinical practice. gout. N Engl J Med. 364:443–452. 2011. View Article : Google Scholar : PubMed/NCBI

26 

Kanellis J and Kang DH: Uric acid as a mediator of endothelial dysfunction, inflammation and vascular disease. Semin Nephrol. 25:39–42. 2005. View Article : Google Scholar : PubMed/NCBI

27 

Sautin YY and Johnson RJ: Uric acid: The oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids. 27:608–619. 2008. View Article : Google Scholar : PubMed/NCBI

28 

Proctor PH: Uric acid: Neuroprotective or neurotoxic? Stroke. 39:e882008. View Article : Google Scholar : PubMed/NCBI

29 

Dawson J, Quinn T, Lees K and Walters M: The continued yin and yang of uric acid. Stroke. 39:e92008. View Article : Google Scholar : PubMed/NCBI

30 

Proctor PH: Uric acid and neuroprotection. Stroke. 39:e1262008. View Article : Google Scholar : PubMed/NCBI

31 

Lipton P: Ischemic cell death in brain neurons. Physiol Rev. 79:1431–1568. 1999.PubMed/NCBI

32 

Amaro S, Soy D, Obach V, Cervera A, Planas AM and Chamorro A: A pilot study of dual treatment with recombinant tissue plasminogen activator and uric acid in acute ischemic stroke. Stroke. 38:2173–2175. 2007. View Article : Google Scholar : PubMed/NCBI

33 

Brouns R, Wauters A, Van De Vijver G, De Surgeloose D, Sheorajpanday R and De Deyn PP: Decrease in uric acid in acute ischemic stroke correlates with stroke severity, evolution and outcome. Clin Chem Lab Med. 48:383–390. 2010. View Article : Google Scholar : PubMed/NCBI

34 

Onetti Y, Dantas AP, Pérez B, Cugota R, Chamorro A, Planas AM, Vila E and Jiménez-Altayó F: Middle cerebral artery remodeling following transient brain ischemia is linked to early postischemic hyperemia: A target of uric acid treatment. Am J Physiol Heart Circ Physiol. 308:H862–H874. 2015. View Article : Google Scholar : PubMed/NCBI

35 

Hooper DC, Spitsin S, Kean RB, Champion JM, Dickson GM, Chaudhry I and Koprowski H: Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis. Proc Natl Acad Sci USA. 95:pp. 675–680. 1998, View Article : Google Scholar : PubMed/NCBI

36 

Nudelman Y and Tunkel AR: Bacterial meningitis: Epidemiology, pathogenesis and management update. Drugs. 69:2577–2596. 2009. View Article : Google Scholar : PubMed/NCBI

37 

Liechti FD, Grandgirard D and Leib SL: Bacterial meningitis: Insights into pathogenesis and evaluation of new treatment options: A perspective from experimental studies. Future Microbiol. 10:1195–1213. 2015. View Article : Google Scholar : PubMed/NCBI

38 

Aycicek A, Iscan A, Erel O, Akcali M and Ocak AR: Oxidant and antioxidant parameters in the treatment of meningitis. Pediatr Neurol. 37:117–120. 2007. View Article : Google Scholar : PubMed/NCBI

39 

Checconi P, Salzano S, Bowler L, Mullen L, Mengozzi M, Hanschmann EM, Lillig CH, Sgarbanti R, Panella S, Nencioni L, et al: Redox proteomics of the inflammatory secretome identifies a common set of redoxins and other glutathionylated proteins released in inflammation, influenza virus infection and oxidative stress. PLoS One. 10:e01270862015. View Article : Google Scholar : PubMed/NCBI

40 

Zuwała-Jagiełło J, Warwas M and Pazgan-Simon M: Ischemia-modified albumin (IMA) is increased in patients with chronic hepatitis C infection and related to markers of oxidative stress and inflammation. Acta Biochim Pol. 59:661–667. 2012.PubMed/NCBI

41 

Komaravelli N and Casola A: Respiratory Viral Infections and subversion of cellular antioxidant defenses. J Pharmacogenomics Pharmacoproteomics. 5:10001412014.PubMed/NCBI

42 

Ngondi JL, Oben J, Forkah DM, Etame LH and Mbanya D: The effect of different combination therapies on oxidative stress markers in HIV infected patients in Cameroon. AIDS Res Ther. 3:192006. View Article : Google Scholar : PubMed/NCBI

43 

Chakraborty SP, Das S, Chattopadhyay S, Tripathy S, Dash SK, Pramanik P and Roy S: Staphylococcus aureus infection induced redox signaling and DNA fragmentation in T-lymphocytes: Possible ameliorative role of nanoconjugated vancomycin. Toxicol Mech Methods. 22:193–204. 2012. View Article : Google Scholar : PubMed/NCBI

44 

Aslan M, Nazligul Y, Horoz M, Bolukbas C, Bolukbas FF, Aksoy N, Celik H and Erel O: Serum prolidase activity and oxidative status in Helicobacter pylori infection. Clin Biochem. 40:37–40. 2007. View Article : Google Scholar : PubMed/NCBI

45 

Hébert-Schuster M, Borderie D, Grange PA, Lemarechal H, Kavian-Tessler N, Batteux F and Dupin N: Oxidative stress markers are increased since early stages of infection in syphilitic patients. Arch Dermatol Res. 304:689–697. 2012. View Article : Google Scholar : PubMed/NCBI

46 

Kariya C, Chu HW, Huang J, Leitner H, Martin RJ and Day BJ: Mycoplasma pneumoniae infection and environmental tobacco smoke inhibit lung glutathione adaptive responses and increase oxidative stress. Infect Immun. 76:4455–4462. 2008. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang L, Zhou P, Meng Z, Gong L, Pang C, Li X, Jia Q, Tan J, Liu N, Hu T, Hu T, et al: Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women. Mol Clin Oncol 7: 1039-1044, 2017.
APA
Zhang, L., Zhou, P., Meng, Z., Gong, L., Pang, C., Li, X. ... Song, K. (2017). Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women. Molecular and Clinical Oncology, 7, 1039-1044. https://doi.org/10.3892/mco.2017.1433
MLA
Zhang, L., Zhou, P., Meng, Z., Gong, L., Pang, C., Li, X., Jia, Q., Tan, J., Liu, N., Hu, T., Zhang, Q., Jia, Q., Song, K."Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women". Molecular and Clinical Oncology 7.6 (2017): 1039-1044.
Chicago
Zhang, L., Zhou, P., Meng, Z., Gong, L., Pang, C., Li, X., Jia, Q., Tan, J., Liu, N., Hu, T., Zhang, Q., Jia, Q., Song, K."Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women". Molecular and Clinical Oncology 7, no. 6 (2017): 1039-1044. https://doi.org/10.3892/mco.2017.1433
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang L, Zhou P, Meng Z, Gong L, Pang C, Li X, Jia Q, Tan J, Liu N, Hu T, Hu T, et al: Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women. Mol Clin Oncol 7: 1039-1044, 2017.
APA
Zhang, L., Zhou, P., Meng, Z., Gong, L., Pang, C., Li, X. ... Song, K. (2017). Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women. Molecular and Clinical Oncology, 7, 1039-1044. https://doi.org/10.3892/mco.2017.1433
MLA
Zhang, L., Zhou, P., Meng, Z., Gong, L., Pang, C., Li, X., Jia, Q., Tan, J., Liu, N., Hu, T., Zhang, Q., Jia, Q., Song, K."Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women". Molecular and Clinical Oncology 7.6 (2017): 1039-1044.
Chicago
Zhang, L., Zhou, P., Meng, Z., Gong, L., Pang, C., Li, X., Jia, Q., Tan, J., Liu, N., Hu, T., Zhang, Q., Jia, Q., Song, K."Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women". Molecular and Clinical Oncology 7, no. 6 (2017): 1039-1044. https://doi.org/10.3892/mco.2017.1433
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