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Article

S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer

  • Authors:
    • Katsuhiro Okuda
    • Motoki Yano
    • Tsutomu Tatematsu
    • Katsumi Nakamae
    • Takeshi Yamada
    • Toshio Kasugai
    • Tsutomu Nishida
    • Masaaki Sano
    • Satoru Moriyama
    • Hiroshi Haneda
    • Osamu Kawano
    • Ryoichi Nakanishi
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467‑8601, Japan, Department of Surgery, Nagoya West Medical Center, Nagoya, Aichi 462‑8508, Japan, Department of Surgery, Kariya Toyota General Hospital, Kariya, Aichi 448‑8505, Japan, Department of Surgery, Matsunami General Hospital, Hashima, Gifu 501‑6062, Japan, Department of Surgery, Toyokawa Hospital, Toyokawa, Aichi 442‑8561, Japan, Department of Surgery, Nagoya Memorial Hospital, Nagoya, Aichi 468‑8520, Japan
  • Pages: 73-79
    |
    Published online on: November 2, 2017
       https://doi.org/10.3892/mco.2017.1481
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Abstract

The majority of patients with completely resected stage II or IIIA non‑small‑cell lung cancer (NSCLC) require adjuvant chemotherapy to improve survival following surgery. In the present trial, the 2‑year disease‑free survival (DFS), and the feasibility and safety of S‑1 as an adjuvant chemotherapy for advanced lung cancer were evaluated. A total of 40 patients with completely resected stage II or IIIA NSCLC were enrolled and randomized to receive postoperative chemotherapy with either up to 4 cycles of paclitaxel plus carboplatin (arm A) or with up to 1 year of S‑1 (arm B). The primary endpoint was 2‑year DFS. The secondary endpoints were feasibility and toxicity. A total of 40 patients were enrolled, but 3 were excluded in accordance with the exclusion criteria. The remaining 37 patients were analyzed. The 2‑year DFS rate was 54.2% in arm A and 84.2% in arm B. Overall, 15/18 (83.3%) patients completed 4 cycles of paclitaxel plus carboplatin and 13/19 (68.4%) completed 1‑year of S‑1adjuvant chemotherapy. Of the 18 (16.7%) patients in arm A, 3 experienced grade 3 or 4 adverse events, while none in arm B experienced such events. Therefore, S‑1 chemotherapy for patients with completely resected stage II or IIIA NSCLC was a feasible and safe regimen, and it may therefore be considered as a potential adjuvant chemotherapy option for advanced NSCLC.
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View References

1 

Asamura H, Goya T, Koshiishi Y, Sohara Y, Eguchi K, Mori M, Nakanishi Y, Tsuchiya R, Shimokata K, Inoue H, et al: A Japanese lung cancer registry study: Prognosis of 13,010 resected lung cancers. J Thorac Oncol. 3:46–52. 2008. View Article : Google Scholar : PubMed/NCBI

2 

Pignon JP, Tribodet H, Scagliotti GV, Douillard JY, Shepherd FA, Stephens RJ, Dunant A, Torri V, Rosell R, Seymour L, et al: Lung adjuvant cisplatin evaluation: A pooled analysis by the LACE collaborative group. J Clin Oncol. 26:3552–3559. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Pisters KM, Evans WK, Azzoli CG, Kris MG, Smith CA, Desch CE, Somefield MR, Brouwers MC, Darling G, Ellis PM, et al: Cancer care onario and American society of clinical oncology adjuvant chemotherapy and adjuvant radiation therapy for stages I–IIIA resectable non-small cell lung cancer guideline. J Clin Oncol. 25:5506–5518. 2007. View Article : Google Scholar : PubMed/NCBI

4 

Crinò L, Weder W, van Meerbeeck J and Felip E; ESMO Guidelines Working Group, : Early stage and locally acvanced (non-metastatic) non-small-cell lung cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 21 Suppl 5:v103–v115. 2010. View Article : Google Scholar : PubMed/NCBI

5 

NSCLC Meta-analyses Collaborative Group, ; Arriagada R, Auperin A, Burdett S, Higgins JP, Johnson DH, Le Chevalier T, LePecoux C, Parmar MK, Pignon JP, et al: Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: Two meta-analyses of individual patient data. Lancet. 375:1267–1277. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Fruh M, Rolland E, Pignon JP, Seymour L, Ding K, Tribodet H, Winton T, Le Chevalier T, Scagliotti GV, Douillard JY, et al: Pooled analysis of the effect of age on adjuvant cisplatin-based chemotherapy for completely resected non-small-cell lung cancer. J Clin Oncol. 26:3573–3581. 2008. View Article : Google Scholar : PubMed/NCBI

7 

Hotta K, Matsuo K, Ueoka H, Kiura K, Tabata M and Tanimoto M: Role of adjuvant chemotherapy in patients with resected non-small-cell lung cancer: Reappraisal with meta-analysis of randomized controlled trials. J Clin Oncol. 22:3860–3867. 2004. View Article : Google Scholar : PubMed/NCBI

8 

Sedrakyan A, van der Meullen J, O'Byrne K, Prendiville J, Hill J and Treasure T: Postoperative chemotherapy for non-small cell lung cancer: A systematic review and meta-analysis. J Thorac Cardiovasc Surg. 128:414–419. 2004. View Article : Google Scholar : PubMed/NCBI

9 

Berghmans T, Paesmans M, Meert AP, Mascaux C, Lothaire P, Lafitte JJ and Sculier JP: Survival improvement in resectable non-small cell lung cancer with (neo)adjuvant chemotherapy: Results of a meta-analysis of the literature. Lung Cancer. 49:13–23. 2005. View Article : Google Scholar : PubMed/NCBI

10 

Kelly K, Crowley J, Bunn PA Jr, Presant CA, Grevstad PK, Moinpour CM, Ramsey SD, Wozniak AJ, Weiss GR, Moore DF, et al: Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: A southwest oncology group trial. J Clin Oncol. 19:3210–3218. 2001. View Article : Google Scholar : PubMed/NCBI

11 

Ohe Y, Ohashi Y, Kubota K, Tamura T, Nkagawa K, Negoro S, Nishiwaki Y, Saijo N, Ariyoshi Y and Fukuoka M: Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm cooperative study in Japan. Ann Oncol. 18:317–323. 2007. View Article : Google Scholar : PubMed/NCBI

12 

Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, Zhu J and Johnson DH; Eastern Cooperative Oncology Group, : Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 346:92–98. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Yamashita Y, Kataoka K, Ishida T, Matsuura M, Seno N, Mukaida H, Miyahara E, Miyata Y, Okita R, Shimizu K, et al: A feasibility study of postoperative adjuvant therapy of carboplatin and weekly paclitaxel for completely resected non-small cell lung cancer. J Thorac Oncol. 3:612–616. 2008. View Article : Google Scholar : PubMed/NCBI

14 

Maruyama R, Yoshino I, Tokunaga S, Ohta M, Kato M, Yoshimine H, Yamazaki K, Nakanishi Y and Ichinose Y: Feasibility trial of adjuvant chemotherapy with paclitaxel and carboplatin after surgical resection in Japanese patients with non-small cell lung cancer: Report of the lung oncology group in kyushu (LOGIK) protocol 0501. Gen Thorac Cardiovasc Surg. 56:68–73. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Ichiki M, Kawasaki M, Takayama K, Ninomiya K, Kuba M, Iwami F, Miyazaki N, Oishi K, Takeo S, Aizawa H and Nakanishi Y: A multicenter phase II study of carboplatin and paclitaxel with a biweekly schedule in patients with advanced non-small-cell lung cancer: Kyushu thoracic oncology group trial. Cancer Chemother Pharmacol. 58:368–373. 2006. View Article : Google Scholar : PubMed/NCBI

16 

Strauss GM, Herndon JE II, Maddaus MA, Johnstone DW, Johnson EA, Harpole DH, Gilenwater HH, Watson DM, Sugarbaker DJ, Schilsky RL, et al: Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the cancer and leukemia group B, radiation therapy oncology group and north central cancer treatment group study groups. J Clin Oncol. 26:5043–5051. 2008. View Article : Google Scholar : PubMed/NCBI

17 

Sugaya M, Uramoto H, Uchiyama A, Nagashima A, Nakanishi R, Sakata H, Nakanishi K, Hanagiri T and Uasumoto K.: PPhase II trial of adjuvant chemotherapy with bi-weekly carboplatin plus paclitaxel in patients with completely resected non-small cell lung cancer. Anticancer Res. 30:3039–3044. 2010.PubMed/NCBI

18 

Shirasaka T, Nakano K, Takechi T, Satake H, Uchida J, Fujioka A, Saito H, Okabe H, Oyama K, Takeda S, et al: Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. Cancer Res. 56:2602–2606. 1996.PubMed/NCBI

19 

Sakuramoto S, Ssako M, Yamaguchi T, Kinoshita T, Fujii M, Nashimoto A, Furukawa H, Nakajima T, Ohashi Y, Imamura H, et al: Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med. 357:1810–1820. 2007. View Article : Google Scholar : PubMed/NCBI

20 

Foukakis T, Lundell L, Gubanski M and Lind PA: Advances in the treatment of patients with gastric adenocarcinoma. Acta Oncol. 46:277–285. 2007. View Article : Google Scholar : PubMed/NCBI

21 

Sasako M: Surgery and adjuvant chemotherapy. Int J Clin Oncol. 13:193–195. 2008. View Article : Google Scholar : PubMed/NCBI

22 

Iwamoto Y, Mitsudomi T, Sakai K, Ymanaka T, Yoshioka H, Takahama M, Yoshimura M, Yoshino I, Takeda M, Sugawara S, et al: Randomized phase II study of adjuvant chemotherapy with long-term S-1 versus Cisplatin+S-1 in completely resected stage II–IIIA non-small cell lung cancer. Clin Cancer Res. 21:5245–5252. 2015. View Article : Google Scholar : PubMed/NCBI

23 

Okumura S, Sasaki T, Satoh K, Kitada M, Nagase A, Yatsuyanagi E and Ohsaki Y: Feasibility of adjuvant chemotherapy with S-1 consisting of a 4-week administration and a two-week rest period in patients with completely resected non-small cell lung cancer. Mol Clin Oncol. 1:124–130. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Soh J, Okumura N, Nakata M, Nakamura H, Fukuda M, Kataoka M, Kajiwara S, Sano Y, Aoe M, Kataoka K, et al: Randomized feasibility study of S-1 for adjuvant chemotherapy in completely resected Stage IA non-small-cell lung cancer: Results of the setouchi lng cancer group study 0701. Jpn J Clin Oncol. 46:741–747. 2016. View Article : Google Scholar : PubMed/NCBI

25 

TNM Classification of Malignant Tumours. Wiley-Blackwell; Oxford: 2009

26 

Calvert AH, Newell DR, Gumbrell LA, O'Reilly S, Burnell M, Boxall FE, Siddik ZH, Judson IR, Gore ME and Wiltshaw E: Carboplatin dosage: Prospective evaluation of a simple formula based on renal function. J Clin Oncol. 7:1748–1756. 1989. View Article : Google Scholar : PubMed/NCBI

27 

Jellifie RW and Jelliffe SM: A computer program for estimation of creatine clearance from unstable serum creatine levels, age, sex and weight. Math Biosci. 14:17–24. 1972. View Article : Google Scholar

28 

Cancer Therapy Evaluation Program (CTEP), . Common Terminology Criteria for Adverse Events, version 3.0, DCTD, NCI, NIH, DHHS. March 31–2003, http://ctep.cancer.govAugust 9–2006

29 

Kawamura M, Eguchi K, Izumi Y, Ymato Y, Koike T, Sakaguchi H, Hada E and Kobayashi K: Phase II trial of gemcitabine and docetaxel in patients with completely resected stage IIA-IIIA non-small-cell lung cancer. Cancer Chemother Pharmacol. 60:495–501. 2007. View Article : Google Scholar : PubMed/NCBI

30 

Kanda Y: Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant. 48:452–458. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Vallières E, Shepherd FA, Crowley J, Van Houtte P, Postmus PE, Carney D, Chansky K, Shaikh Z and Goldstraw P; International Association for the Study of Lung Cancer International Staging Committee and Participating Institutions, : The IASLC lung cancer staging project: Proposals regarding the relevance of TNM in the pathologic staging of small cell lung cancer in the forthcoming (seventh) edition of the TNM classification for lung cancer. J Thorac Oncol. 4:1049–1059. 2009. View Article : Google Scholar : PubMed/NCBI

32 

Kato H, Ichinose Y, Ohta M, Hata E, Tsubota N, Tada H, Watanabe Y, Wada H, Tsuboi M, Hamajima N, et al: A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. N Engl J Med. 350:1713–1721. 2004. View Article : Google Scholar : PubMed/NCBI

33 

Tsukuda M, Kida A, Fujii M, Kono N, Yoshihara T, Hasegawa Y and Sugita M; Chemotherapy Study Group of Head and Neck Cancer, : Randomized scheduling feasibility study of S-1 for adjuvant chemotherapy in advanced head and neck cancer. Br J Cancer. 93:884–889. 2005. View Article : Google Scholar : PubMed/NCBI

34 

Shigekawa T, Osaki A, Sekine H, Sato N, Kanbayashi C, Sano H, Takeuchi H, Ueda S, Nakamiya N, Sugitani I, et al: SSafety and feasibility of adjuvant chemotherapy with S-1 in Japanese breast cancer patients after primary systemic chemotherapy: A feasibility study. BMC Cancer. 15:2532015. View Article : Google Scholar : PubMed/NCBI

35 

Yano T, Yamazaki K, Maruyama R, Tokunaga S, Shoji F, Higashi H, Takeo S, Ichinose Y and Maehara Y; Lung Oncology Group in Kyushu (LOGIK), : Feasibility study of postoperative adjuvant chemotherapy with S-1 (tegaful, gimeracil, oteracil potassium) for non-small cell lung cancer-LOGIK 0601 study. Lung Cancer. 67:184–187. 2010. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Okuda K, Yano M, Tatematsu T, Nakamae K, Yamada T, Kasugai T, Nishida T, Sano M, Moriyama S, Haneda H, Haneda H, et al: S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer. Mol Clin Oncol 8: 73-79, 2018.
APA
Okuda, K., Yano, M., Tatematsu, T., Nakamae, K., Yamada, T., Kasugai, T. ... Nakanishi, R. (2018). S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer. Molecular and Clinical Oncology, 8, 73-79. https://doi.org/10.3892/mco.2017.1481
MLA
Okuda, K., Yano, M., Tatematsu, T., Nakamae, K., Yamada, T., Kasugai, T., Nishida, T., Sano, M., Moriyama, S., Haneda, H., Kawano, O., Nakanishi, R."S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer". Molecular and Clinical Oncology 8.1 (2018): 73-79.
Chicago
Okuda, K., Yano, M., Tatematsu, T., Nakamae, K., Yamada, T., Kasugai, T., Nishida, T., Sano, M., Moriyama, S., Haneda, H., Kawano, O., Nakanishi, R."S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer". Molecular and Clinical Oncology 8, no. 1 (2018): 73-79. https://doi.org/10.3892/mco.2017.1481
Copy and paste a formatted citation
x
Spandidos Publications style
Okuda K, Yano M, Tatematsu T, Nakamae K, Yamada T, Kasugai T, Nishida T, Sano M, Moriyama S, Haneda H, Haneda H, et al: S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer. Mol Clin Oncol 8: 73-79, 2018.
APA
Okuda, K., Yano, M., Tatematsu, T., Nakamae, K., Yamada, T., Kasugai, T. ... Nakanishi, R. (2018). S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer. Molecular and Clinical Oncology, 8, 73-79. https://doi.org/10.3892/mco.2017.1481
MLA
Okuda, K., Yano, M., Tatematsu, T., Nakamae, K., Yamada, T., Kasugai, T., Nishida, T., Sano, M., Moriyama, S., Haneda, H., Kawano, O., Nakanishi, R."S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer". Molecular and Clinical Oncology 8.1 (2018): 73-79.
Chicago
Okuda, K., Yano, M., Tatematsu, T., Nakamae, K., Yamada, T., Kasugai, T., Nishida, T., Sano, M., Moriyama, S., Haneda, H., Kawano, O., Nakanishi, R."S-1 vs. paclitaxel plus carboplatin as adjuvant chemotherapy for completely resected stage II/IIIA non‑small‑cell lung cancer". Molecular and Clinical Oncology 8, no. 1 (2018): 73-79. https://doi.org/10.3892/mco.2017.1481
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