Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
January-2018 Volume 8 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2018 Volume 8 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report

  • Authors:
    • Hiroshi Yamazaki
    • Masashi Sasaki
    • Ken‑Ichi Aoyama
    • Takatsugu Suzuki
    • Yuya Denda
    • Masahiro Uchibori
    • Yasuhiro Nakanishi
    • Rena Kojima
    • Yoshihide Ota
  • View Affiliations / Copyright

    Affiliations: Department of Oral and Maxillofacial Surgery, Tokai University School of Medicine, Isehara, Kanagawa 259‑1193, Japan
    Copyright: © Yamazaki et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 68-72
    |
    Published online on: November 13, 2017
       https://doi.org/10.3892/mco.2017.1496
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Lateral retropharyngeal lymph node (LRPLN) is located between the internal carotid artery and the prevertebral muscles. Metastasis to the LRPLN is frequent in nasopharyngeal cancer, but is rare in oral cancer. The prognosis of patients with oral cancer with LRPLN metastasis is usually poor. The present study reported a patient with LRPLN metastasis from squamous cell carcinoma of the upper gingiva, who survived for >7 years. Docetaxel, cisplatin and fluorouracil (TPF) therapy was performed as induction chemotherapy and it was planned to subsequently conduct chemoradiotherapy or surgery. As the tumor only exhibited a transient response to TPF, surgery was selected. Postoperatively, only radiotherapy was performed and a favorable outcome was achieved.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

View References

1 

Coskun HH, Ferlito A, Medina JE, Robbins KT, Rodrigo JP, Strojan P, Suárez C, Takes RP, Woolgar JA, Shaha AR, et al: Retropharyngeal lymph node metastases in head and neck malignancies. Head Neck. 33:1520–1529. 2011. View Article : Google Scholar : PubMed/NCBI

2 

Kimura Y, Hanazawa T, Sano T and Okano T: Lateral retropharyngeal node metastasis from carcinoma of the upper gingiva and maxillary sinus. AJNR Am J Neuroradiol. 19:1221–1224. 1998.PubMed/NCBI

3 

Nishida M, Yasuda S, Murakami K, Yamamura I, Nagata Y and Iizuka T: Retropharyngeal lymph node metastases from oral cancer: A report of 2 patients. J Oral Maxillofac Surg. 63:410–412. 2005. View Article : Google Scholar : PubMed/NCBI

4 

Umeda M, Shigeta T, Takahashi H, Kataoka T, Oguni A, Minamikawa T, Shibuya Y, Yokoo S and Komori T: Metastasis to the lateral retropharyngeal lymph node from squamous cell carcinoma of the oral cavity: Report of three cases. Int J Oral Maxillofac Surg. 38:1004–1008. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Tseng JR, Ho TY, Lin CY, Lee LY, Wang HM, Liao CT and Yen TC: Clinical outcomes of patients with oral cavity squamous cell carcinoma and retropharyngeal lymph node metastasis identified by FDG PET/CT. PLoS One. 8:e797662013. View Article : Google Scholar : PubMed/NCBI

6 

Vermorken JB, Remenar E, van Herpen C, Gorlia T, Mesia R, Degardin M, Stewart JS, Jelic S, Betka J, Preiss JH, et al: Cisplatin, fluorouracil and docetaxel in unresectable head and neck cancer. N Engl J Med. 357:1695–1704. 2007. View Article : Google Scholar : PubMed/NCBI

7 

Posner MR, Hershock DM, Blajman CR, Mickiewicz E, Winquist E, Gorbounova V, Tjulandin S, Shin DM, Cullen K, Ervin TJ, et al: Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med. 357:1705–1715. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Watarai J, Seino Y, Kobayashi M, Shindo M and Kato T: CT of retropharyngeal lymph node metastasis from maxillary carcinoma. Acta Radiol. 34:492–495. 1993. View Article : Google Scholar : PubMed/NCBI

9 

Tauzin M, Rabalais A, Hagan JL, Wood CG, Ferris RL and Walvekar RR: PET-CT staging of the neck in cancers of the oropharynx: Patterns of regional and retropharyngeal nodal metastasis. World J Surg Oncol. 8:702010. View Article : Google Scholar : PubMed/NCBI

10 

Amatsu M, Mohri M and Kinishi M: Significance of retropharyngeal node dissection at radical surgery for carcinoma of the hypopharynx and cervical esophagus. Laryngoscope. 111:1099–1103. 2001. View Article : Google Scholar : PubMed/NCBI

11 

Kamiyama R, Saikawa M and Kishimoto S: Significance of retropharyngeal lymph node dissection in hypopharyngeal cancer. Jpn J Clin Oncol. 39:632–637. 2009. View Article : Google Scholar : PubMed/NCBI

12 

Umeda M, Minamikawa T, Komatsubara H, Ojima Y, Shibuya Y, Yokoo S and Komori T: En bloc resection of the primary tumour and cervical lymph nodes through the parapharyngeal space in patients with squamous cell carcinoma of the maxilla: A preliminary study. Br J Oral Maxillofac Surg. 43:17–22. 2005. View Article : Google Scholar : PubMed/NCBI

13 

Pfister DG, Spencer S, Brizel DM, Burtness B, Busse PM, Caudell JJ, Cmelak AJ, Colevas AD, Dunphy F, Eisele DW, et al: Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 12:1454–1487. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Marta GN, Riera R, Bossi P, Zhong LP, Licitra L, Macedo CR, de Castro Junior G, Carvalho AL, William WN Jr and Kowalski LP: Induction chemotherapy prior to surgery with or without postoperative radiotherapy for oral cavity cancer patients: Systematic review and meta-analysis. Eur J Cancer. 51:2596–2603. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Lau A, Li KY, Yang WF and Su YX: Induction chemotherapy for squamous cell carcinomas of the oral cavity: A cumulative meta-analysis. Oral Oncol. 61:104–114. 2016. View Article : Google Scholar : PubMed/NCBI

16 

Grégoire V, Lefebvre JL, Licitra L and Felip E: EHNS-ESMO-ESTRO Guidelines Working Group: Squamous cell carcinoma of the head and neck: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 21 Suppl 5:v184–v186. 2010. View Article : Google Scholar : PubMed/NCBI

17 

Teo M, Karakaya E, Young CA, Dyker KE, Coyle C, Sen M and Prestwich RJ: The efficacy of induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil combined with cisplatin concurrent chemoradiotherapy for locally advanced head and neck squamous cell carcinoma: A matched pair analysis. Clin Oncol (R Coll Radiol). 25:647–653. 2013. View Article : Google Scholar : PubMed/NCBI

18 

Zhang L, Jiang N, Shi Y, Li S, Wang P and Zhao Y: Induction chemotherapy with concurrent chemoradiotherapy versus concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of head and neck: A meta-analysis. Sci Rep. 5:107982015. View Article : Google Scholar : PubMed/NCBI

19 

Hitt R, Grau JJ, López-Pousa A, Berrocal A, García-Girón C, Irigoyen A, Sastre J, Martínez-Trufero J, Brandariz Castelo JA, Verger E, et al: A randomized phase III trial comparing induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as treatment of unresectable head and neck cancer. Ann Oncol. 25:216–225. 2014. View Article : Google Scholar : PubMed/NCBI

20 

Budach W, Bölke E, Kammers K, Gerber PA, Orth K, Gripp S and Matuschek C: Induction chemotherapy followed by concurrent radio-chemotherapy versus concurrent radio-chemotherapy alone as treatment of locally advanced squamous cell carcinoma of the head and neck (HNSCC): A meta-analysis of randomized trials. Radiother Oncol. 118:238–243. 2016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yamazaki H, Sasaki M, Aoyama KI, Suzuki T, Denda Y, Uchibori M, Nakanishi Y, Kojima R and Ota Y: Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report. Mol Clin Oncol 8: 68-72, 2018.
APA
Yamazaki, H., Sasaki, M., Aoyama, K., Suzuki, T., Denda, Y., Uchibori, M. ... Ota, Y. (2018). Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report. Molecular and Clinical Oncology, 8, 68-72. https://doi.org/10.3892/mco.2017.1496
MLA
Yamazaki, H., Sasaki, M., Aoyama, K., Suzuki, T., Denda, Y., Uchibori, M., Nakanishi, Y., Kojima, R., Ota, Y."Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report". Molecular and Clinical Oncology 8.1 (2018): 68-72.
Chicago
Yamazaki, H., Sasaki, M., Aoyama, K., Suzuki, T., Denda, Y., Uchibori, M., Nakanishi, Y., Kojima, R., Ota, Y."Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report". Molecular and Clinical Oncology 8, no. 1 (2018): 68-72. https://doi.org/10.3892/mco.2017.1496
Copy and paste a formatted citation
x
Spandidos Publications style
Yamazaki H, Sasaki M, Aoyama KI, Suzuki T, Denda Y, Uchibori M, Nakanishi Y, Kojima R and Ota Y: Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report. Mol Clin Oncol 8: 68-72, 2018.
APA
Yamazaki, H., Sasaki, M., Aoyama, K., Suzuki, T., Denda, Y., Uchibori, M. ... Ota, Y. (2018). Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report. Molecular and Clinical Oncology, 8, 68-72. https://doi.org/10.3892/mco.2017.1496
MLA
Yamazaki, H., Sasaki, M., Aoyama, K., Suzuki, T., Denda, Y., Uchibori, M., Nakanishi, Y., Kojima, R., Ota, Y."Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report". Molecular and Clinical Oncology 8.1 (2018): 68-72.
Chicago
Yamazaki, H., Sasaki, M., Aoyama, K., Suzuki, T., Denda, Y., Uchibori, M., Nakanishi, Y., Kojima, R., Ota, Y."Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report". Molecular and Clinical Oncology 8, no. 1 (2018): 68-72. https://doi.org/10.3892/mco.2017.1496
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team