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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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January-2018 Volume 8 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Case Report

Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report

  • Authors:
    • Xiang Pan
    • Jing Quan
    • Liwen Zhao
    • Wenhua Li
    • Benlin Wei
    • Shangqi Yang
    • Yongqing Lai
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China
  • Pages: 83-85
    |
    Published online on: November 13, 2017
       https://doi.org/10.3892/mco.2017.1497
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Abstract

Xp11.2 translocation renal cell carcinoma (RCC) with transcription factor E3 (TFE3) gene fusion is a rare tumor, and the prognosis of this tumor is poorer compared with that of other subtypes of RCC. The patient presented herein was a 70‑year‑old man who presented with a solid mass sized ~8.2x6.1 cm in the right kidney and underwent radical right nephrectomy. Following pathological and immunohistochemical (IHC) examination and fluorescent in situ hybridization (FISH), the patient was diagnosed with Xp11.2 translocation RCC with TFE3 gene fusion. These tumors are more commonly encountered in children rather than in adults, and adult Xp11.2 translocation RCC is associated with a poorer prognosis compared with its pediatric counterpart. IHC assay and FISH are important diagnostic methods. However, there is currently no established effective treatment for Xp11.2 RCC.
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Copy and paste a formatted citation
Spandidos Publications style
Pan X, Quan J, Zhao L, Li W, Wei B, Yang S and Lai Y: Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report. Mol Clin Oncol 8: 83-85, 2018.
APA
Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., & Lai, Y. (2018). Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report. Molecular and Clinical Oncology, 8, 83-85. https://doi.org/10.3892/mco.2017.1497
MLA
Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., Lai, Y."Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report". Molecular and Clinical Oncology 8.1 (2018): 83-85.
Chicago
Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., Lai, Y."Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report". Molecular and Clinical Oncology 8, no. 1 (2018): 83-85. https://doi.org/10.3892/mco.2017.1497
Copy and paste a formatted citation
x
Spandidos Publications style
Pan X, Quan J, Zhao L, Li W, Wei B, Yang S and Lai Y: Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report. Mol Clin Oncol 8: 83-85, 2018.
APA
Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., & Lai, Y. (2018). Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report. Molecular and Clinical Oncology, 8, 83-85. https://doi.org/10.3892/mco.2017.1497
MLA
Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., Lai, Y."Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report". Molecular and Clinical Oncology 8.1 (2018): 83-85.
Chicago
Pan, X., Quan, J., Zhao, L., Li, W., Wei, B., Yang, S., Lai, Y."Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report". Molecular and Clinical Oncology 8, no. 1 (2018): 83-85. https://doi.org/10.3892/mco.2017.1497
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