Multilocular cystic renal cell carcinoma: A case report and review of the literature

Hu,Jia; Jin,Lu; Li,Yifan; He,Tao; Liu,Jiaju; Shi,Bentao; Yang,Shangqi; Gui,Yaoting; Mao,Xiangming; Lai,Yongqing; Ni,Liangchao

doi:10.3892/mco.2017.1526

February-2018 Volume 8 Issue 2

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

February-2018 Volume 8 Issue 2

Full Size Image

Case Report

Multilocular cystic renal cell carcinoma: A case report and review of the literature

Authors:
- Jia Hu
- Lu Jin
- Yifan Li
- Tao He
- Jiaju Liu
- Bentao Shi
- Shangqi Yang
- Yaoting Gui
- Xiangming Mao
- Yongqing Lai
- Liangchao Ni
View Affiliations / Copyright

Affiliations: Department of Urology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China, Guangdong Key Laboratory of Male Reproductive Medicine and Genetics, Peking University Shenzhen Hospital, Shenzhen PKU‑HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China
Pages: 326-329
|
Published online on: December 8, 2017

https://doi.org/10.3892/mco.2017.1526
Expand metrics +

Abstract

Multilocular cystic renal cell carcinoma (MCRCC), which exhibits low‑stage and low‑grade characteristics, is a special type of RCC. MCRCC is extremely rare and generally develops at ages >50 years. We herein report a case of MCRCC in a 28‑year‑old man, which, to the best of our knowledge, is the youngest case reported worldwide to date. The patient presented with irritative bladder symptoms for 1 year. Dynamic enhanced computed tomography (CT) imaging revealed a mass with inhomogeneous enhancement in the left kidney, with a rich blood supply. B‑ultrasonography also revealed a renal protruding mass. As the mass was highly suspicious to be a malignant tumor, laparoscopic radical nephrectomy was performed and MCRCC was definitively diagnosed by pathological examination. The patient has been regularly followed up for 6 months, without complications or disease recurrence.

View Figures

View References

1	Cheng L and Huang W: Multilocular cystic clear cell neoplasm of low malignant potential: Evolving concept, classification and unifying terminology. Zhonghua Bing Li Xue Za Zhi. 43:721–722. 2014.(In Chinese). PubMed/NCBI
2	Wahal SP and Mardi K: Multilocular cystic renal cell carcinoma: A rare entity with review of literature. J Lab Physicians. 6:50–52. 2014. View Article : Google Scholar : PubMed/NCBI
3	Ebin JN and Bonsib SM: Extensively cystic renal neoplasms: Cystic nephroma, cystic partially differentiated nephroblastoma, multilocular cystic renal cell carcinoma, and cystic hamartoma of renal pelvis. Semin Diagn Pathol. 15:2–20. 1998.PubMed/NCBI
4	Williamson SR, MacLennan GT, Lopez-Beltran A, Montironi R, Tan PH, Martignoni G, Grignon DJ, Eble JN, Idrees MT, Scarpelli M and Cheng L: Cystic partially regressed clear cell renal cell carcinoma: A potential mimic of multilocular cystic renal cell carcinoma. Histopathology. 63:767–779. 2013. View Article : Google Scholar : PubMed/NCBI
5	Tamura Y, Okamura K, Ogura H, Kawada T, Tsuji H, Takahashi Y, Fukabori Y, Kobayashi M, Imai K and Yamanaka H: Multilocular cystic renal cell carcinoma: A report of 2 cases. Hinyokika Kiyo. 36:437–441. 1990.(In Japanese). PubMed/NCBI
6	Ghosh P and Saha K: Multilocular cystic renal cell carcinoma: A rare, unique entity and diagnostic challenge. Arch Iran Med. 17:129–132. 2014.PubMed/NCBI
7	Chowdhury AR, Chakraborty D, Bhattacharya P and Dey RK: Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman. Urol Ann. 5:119–121. 2013. View Article : Google Scholar : PubMed/NCBI
8	Yamaguchi S, Yoshihiro S, Matsuyama H, Nagao K, Fukunaga K, Matsumoto H, Matsuda K, Oba K and Naito K: The allelic loss of chromosome 3p25 with c-myc gain is related to the development of clear-cell renal cell carcinoma. Clin Genet. 63:184–191. 2003. View Article : Google Scholar : PubMed/NCBI
9	Halat SK and MacLennan GT: Multilocular cystic renal cell carcinoma. J Urol. 177:3432007. View Article : Google Scholar : PubMed/NCBI
10	Imura J, Ichikawa K, Takeda J, Tomita S, Yamamoto H, Nakazono M, Takimoto T, Ueda Y and Fujimori T: Multilocular cystic renal cell carcinoma: A clinicopathological, immuno- and lectin histochemical study of nine cases. APMIS. 112:183–191. 2004. View Article : Google Scholar : PubMed/NCBI
11	Singhai A, Babu S, Verma N and Singh V: Multilocular cystic renal cell carcinoma: A rare entity. BMJ Case Rep. 2013:pii: bcr20120084572013. View Article : Google Scholar
12	Deger AN, Capar E, Ucar BI, Deger H and Tayfur M: Adult multicystic nephroma: Case report and review of the literature. J Clin Diagn Res. 9:ED22–ED23. 2015.PubMed/NCBI
13	Guo A, Wei L, Song X and Liu A: Adult wilms tumor with intracaval and intracardiac extension: Report of a case and review of literature. J Cancer. 2:132–135. 2011. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Multilocular cystic renal cell carcinoma: A case report and review of the literature

This article is mentioned in:

Abstract

Figure 1

Figure 2

Related Articles