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Article

18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy

  • Authors:
    • Masahiko Yano
    • Hiroshi Miyata
    • Keijiro Sugimura
    • Masaaki Motoori
    • Takeshi Omori
    • Yoshiyuki Fujiwara
    • Norikatsu Miyoshi
    • Masayoshi Yasui
    • Masayuki Ohue
    • Hirofumi Akita
    • Akira Tomokuni
    • Hidenori Takahashi
    • Shogo Kobayashi
    • Masato Sakon
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterological Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Osaka 537‑8511, Japan
  • Pages: 434-440
    |
    Published online on: January 10, 2018
       https://doi.org/10.3892/mco.2018.1546
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Abstract

Neoadjuvant chemotherapy (NAC) is a promising treatment strategy for advanced esophageal cancer. However, measures of NAC response assessment and prognostic prediction have not yet been established. The aim of this study was to evaluate the usefulness of combined 18F‑fluorodeoxyglucose positron emission tomography̸computed tomography (PET̸CT). A total of 77 patients with stage IB‑IV esophageal cancer who were treated with NAC followed by curative resection were retrospectively analyzed. PET̸CT was performed before and after NAC and 56 patients were clinical responders. The pretreatment maximal standardized uptake value (pre‑SUVmax), post‑SUVmax and %SUVmax were 11.3±5.8, 5.1±4.8 and 49.0±35.1%, respectively, for the main tumors (T) and 4.3±2.8, 2.5±1.9 and 67.0±39.6%, respectively, for the metastatic nodes (N). Among the preoperatively available factors, clinical response (P=0.018), post‑SUVmax‑N (P=0.0001) and %SUVmax‑T (P=0.0031) were significant prognostic factors by univariate analysis. The multivariate analysis identified post‑SUVmax‑N as the only significant prognostic predictor (P=0.0254). Patients with a post‑SUVmax‑N of <3.0 exhibited significantly fewer pathological metastatic nodes and better disease‑free survival compared with patients with a post‑SUVmax‑N >3.0. Therefore, post‑SUVmax‑N may be a useful prognostic predictor in patients with advanced esophageal cancer who are treated with NAC followed by surgery.
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1 

Isono K, Sato H and Nakayama K: Results of a nationwide study on the three-field lymph node dissection of esophageal cancer. Oncology. 48:411–420. 1991. View Article : Google Scholar : PubMed/NCBI

2 

Akiyama H, Tsurumaru M, Udagawa H and Kajiyama Y: Radical lymph node dissection for cancer of the thoracic esophagus. Ann Surg. 220:364–372; discussion 372–373. 1994. View Article : Google Scholar : PubMed/NCBI

3 

Allum WH, Stenning SP, Bancewicz J, Clark PI and Langley RE: Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol. 27:5062–5067. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Cunningham D, Allum WH, Stenning SP, Thompson JN, Van de Velde CJ, Nicolson M, Scarffe JH, Lofts FJ, Falk SJ, Iveson TJ, et al: Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Eng J Med. 355:11–20. 2006. View Article : Google Scholar

5 

Medical Research Council Oesophageal Cancer Working Group, . Surgical resection with or without preoperative chemotherapy in oesophageal cancer: A randomised controlled trial. Lancet. 359:1727–1733. 2002. View Article : Google Scholar : PubMed/NCBI

6 

Gebski V, Burmeister B, Smithers BM, Foo K, Zalcberg J and Simes J; Australasian Gastro-Intestinal Trials Group, : Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: A meta-analysis. Lancet Oncol. 8:226–234. 2007. View Article : Google Scholar : PubMed/NCBI

7 

Kaklamanos IG, Walker GR, Ferry K, Franceschi D and Livingstone AS: Neoadjuvant treatment for resectable cancer of the esophagus and the gastroesophageal junction: A meta-analysis of randomized clinical trials. Ann Surg Oncol. 10:754–761. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Law S, Fok M, Chow S, Chu KM and Wong J: Preoperative chemotherapy versus surgical therapy alone for squamous cell carcinoma of the esophagus: A prospective randomized trial. J Thorac Cardiovasc Surg. 114:210–217. 1997. View Article : Google Scholar : PubMed/NCBI

9 

Ancona E, Ruol A, Santi S, Merigliano S, Sileni VC, Koussis H, Zaninotto G, Bonavina L and Peracchia A: Only pathologic complete response to neoadjuvant chemotherapy improves significantly the long term survival of patients with resectable esophageal squamous cell carcinoma: Final report of a randomized, controlled trial of preoperative chemotherapy versus surgery alone. Cancer. 91:2165–2174. 2001. View Article : Google Scholar : PubMed/NCBI

10 

Block MI, Patterson GA, Sundaresan RS, Bailey MS, Flanagan FL, Dehdashti F, Siegel BA and Cooper JD: Improvement in staging of esophageal cancer with the addition of positron emission tomography. Ann Thorac Surg. 64:770–776; discussion 776–777. 1997. View Article : Google Scholar : PubMed/NCBI

11 

Luketich JD, Schauer PR, Meltzer CC, Landreneau RJ, Urso GK, Townsend DW, Ferson PF, Keenan RJ and Belani CP: Role of positron emission tomography in staging esophageal cancer. Ann Thorac Surg. 64:765–769. 1997. View Article : Google Scholar : PubMed/NCBI

12 

Flanagan FL, Dehdashti F, Siegel BA, Trask DD, Sundaresan SR, Patterson GA and Cooper JD: Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography. AJR Am J Roentgenol. 168:417–424. 1997. View Article : Google Scholar : PubMed/NCBI

13 

Flamen P, Lerut A, Van Custem E, De Wever W, Peeters M, Stroobants S, Dupont P, Bormans G, Hiele M, De Leyn P, et al: Utility of positron emission tomography for the staging of patients with potentially operable esophageal carcinoma. J Clin Oncol. 18:3202–3210. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Brücher BL, Weber W, Bauer M, Fink U, Avril N, Stein HJ, Werner M, Zimmerman F, Siewert JR and Schwaiger M: Neoadjuvant therapy of esophageal squamous cell carcinoma: Response evaluation by positron emission tomography. Ann Surg. 233:300–309. 2001. View Article : Google Scholar : PubMed/NCBI

15 

Weber WA, Ott K, Becker K, Dittler HJ, Helmberger H, Avril NE, Meisetschläger G, Busch R, Siewert JR, Schwaiger M and Fink U: Prediction of response to preoperative chemotherapy in adenocarcinomas of the esophagogastric junction by metabolic imaging. J Clin Oncol. 19:3058–3065. 2001. View Article : Google Scholar : PubMed/NCBI

16 

Flamen P, Van Cutsem E, Lerut A, Cambier JP, Haustermans K, Bormans G, De Leyn P, Van Raemdonck D, De Wever W, Ectors N, et al: Positron emission tomography for assessment of the response to induction radiochemotherapy in locally advanced oesophageal cancer. Ann Oncol. 13:361–368. 2002. View Article : Google Scholar : PubMed/NCBI

17 

Higuchi I, Yasuda T, Yano M, Doki Y, Miyata H, Tatsumi M, Fukunaga H, Takiguchi S, Fujiwara Y, Hatazawa J and Monden M: Lack of fludeoxyglucose F 18 uptake in posttreatment positron emission tomography as a significant predictor of survival after subsequent surgery in multimodality treatment for patients with locally advanced esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. 136:205–212. 2008. View Article : Google Scholar : PubMed/NCBI

18 

Yuan S, Yu Y, Chao KS, Fu Z, Yin Y, Liu T, Chen S, Yang X, Yang G, Guo H and Yu J: Additional value of PET/CT over PET in assessment of locoregional lymph nodes in thoracic esophageal squamous cell cancer. J Nucl Med. 47:1255–1259. 2006.PubMed/NCBI

19 

Sobin LH and Wittekind C: TNM Classification of Malignant Tumors. 6th. Wiley; New York: 2002

20 

Kelsen DP, Heelan R, Coonley C, Bains M, Martini N, Hilaris B and Golbey RB: Clinical and pathological evaluation of response to chemotherapy in patients with esophageal carcinoma. Am J Clin Oncol. 6:539–546. 1983. View Article : Google Scholar : PubMed/NCBI

21 

Ishihara R, Yamamoto S, Iishi H, Nagai K, Matui F, Kawada N, Ohta T, Kanzaki H, Hanafusa M, Hanaoka N, et al: Predicting the effects of chemoradiotherapy for squamous cell carcinoma of the esophagus by induction chemotherapy response assessed by positron emission tomography: Toward PET-response-guided selection of chemoradiotherapy or esophagectomy. Int J Clin Oncol. 17:225–232. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Kawahara K, Maekawa T, Okabayashi K, Shiraishi T, Yoshinaga Y, Yoneda S, Hideshima T and Shirakusa T: The number of lymph node metastases influences survival in esophageal cancer. J Surg Oncol. 67:160–163. 1998. View Article : Google Scholar : PubMed/NCBI

23 

Tachibana M, Kinugasa S, Dhar DK, Kotoh T, Shibakita M, Ohno S, Masunaga R, Kubota H, Kohno H and Nagasue N: Prognostic factors after extended esophagectomy for squamous cell carcinoma of the thoracic esophagus. J Surg Oncol. 72:88–93. 1999. View Article : Google Scholar : PubMed/NCBI

24 

Rizk N, Venkatraman E, Park B, Flores R, Bains MS and Rusch V; American Joint Committee on Cancer staging system, : The prognostic importance of the number of involved lymph nodes in esophageal cancer: Implications for revisions of the American Joint Committee on Cancer staging system. J Thorac Cardiovasc Surg. 132:1374–1381. 2006. View Article : Google Scholar : PubMed/NCBI

25 

Akutsu Y, Shuto K, Kono T, Uesato M, Hoshino I, Shiratori T, Isozaki Y, Akanuma N, Uno T and Matsubara H: The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma. J Surg Oncol. 105:756–760. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Gu Y, Swisher SG, Ajani JA, Correa AM, Hofstetter WL, Liao Z, Komaki RR, Rashid A, Hamilton SR and Wu TT: The number of lymph nodes with metastasis predicts survival in patients with esophageal or esophagogastric junction adenocarcinoma who receive preoperative chemoradiation. Cancer. 106:1017–1025. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Dhar DK, Tachibana M, Kinukawa N, Riruke M, Kohno H, Little AG and Nagasue N: The prognostic significance of lymph node size in patients with squamous esophageal cancer. Ann Surg Oncol. 9:1010–1016. 2002. View Article : Google Scholar : PubMed/NCBI

28 

Komori T, Doki Y, Kabuto T, Ishikawa O, Hiratsuka M, Sasaki Y, Ohigashi H, Murata K, Yamada T, Miyashiro I, et al: Prognostic significance of the size of cancer nests in metastatic lymph nodes in human esophageal cancers. J Surg Oncol. 82:19–27. 2003. View Article : Google Scholar : PubMed/NCBI

29 

Doi N, Imada T, Aoyama N, Kameda Y and Koizumi H: Prognostic significance of the carcinoma area in the thickest part of the lymph node. Hepatogastroenterology. 47:728–732. 2000.PubMed/NCBI

30 

Vesselle H, Schmidt RA, Pugsley JM, Li M, Kohlmyer SG, Vallires E and Wood DE: Lung cancer proliferation correlates with [F-18]fluorodeoxyglucose uptake by positron emission tomography. Clin Cancer Res. 6:3837–3844. 2000.PubMed/NCBI

31 

Jacob R, Welkoborsky HJ, Mann WJ, Jauch M and Amedee R: [Fluorine-18]fluorodeoxyglucose positron emission tomography, DNA ploidy and growth fraction in squamous-cell carcinomas of the head and neck. ORL J Otorhinolaryngol Relat Spec. 63:307–313. 2001. View Article : Google Scholar : PubMed/NCBI

32 

Strauss LG, Koczan D, Klippel S, Pan L, Cheng C, Willis S and Haberkorn U: Dimitrakopoulou-Strauss A: Impact of angiogenesis-related gene expression on the tracer kinetics of 18F-FDG in colorectal tumors. J Nucl Med. 49:1238–1244. 2008. View Article : Google Scholar : PubMed/NCBI

33 

Kaira K, Oriuchi N, Sunaga N, Ishizuka T, Shimizu K and Yamamoto N: A systemic review of PET and biology in lung cancer. Am J Transl Res. 3:383–391. 2011.PubMed/NCBI

34 

Rebollo Aguirre AC, Ramos-Font C, Villegas Portero R, Cook GJ, Llamas Elvira JM and Tabares AR: 18F-fluorodeoxyglucose positron emission tomography for the evaluation of neoadjuvant therapy response in esophageal cancer: Systematic review of the literature. Ann Surg. 250:247–254. 2009. View Article : Google Scholar : PubMed/NCBI

35 

Kwee RM: Prediction of tumor response to neoadjuvant therapy in patients with esophageal cancer with use of 18F FDG PET: A systematic review. Radiology. 254:707–717. 2010. View Article : Google Scholar : PubMed/NCBI

36 

Smith JW, Moreira J, Abood G, Aranha GV, Nagda S, Wagner RH and Shoup M: The influence of (18)flourodeoxyglucose positron emission tomography on the management of gastroesophageal junction carcinoma. Am J Surg. 197:308–312. 2009. View Article : Google Scholar : PubMed/NCBI

37 

Port JL, Lee PC, Korst RJ, Liss Y, Meherally D, Christos P, Mazumdar M and Altorki NK: Positron emission tomographic scanning predicts survival after induction chemotherapy for esophageal carcinoma. Ann Thorac Surg. 84:393–400; discussion 400. 2007. View Article : Google Scholar : PubMed/NCBI

38 

Roedl JB, Harisinghani MG, Colen RR, Fischman AJ, Blake MA, Mathisen DJ and Mueller PR: Assessment of treatment response and recurrence in esophageal carcinoma based on tumor length and standardized uptake value on positron emission tomography-computed tomography. Ann Thorac Surg. 86:1131–1138. 2008. View Article : Google Scholar : PubMed/NCBI

39 

Suzuki A, Xiao L, Hayashi Y, Macapinlac HA, Welsh J, Lin SH, Lee JH, Bhutani MS, Maru DM, Hofstetter WL, et al: Prognostic significance of baseline positron emission tomography and importance of clinical complete response in patients with esophageal or gastroesophageal junction cancer treated with definitive chemoradiotherapy. Cancer. 117:4823–4833. 2011. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Yano M, Miyata H, Sugimura K, Motoori M, Omori T, Fujiwara Y, Miyoshi N, Yasui M, Ohue M, Akita H, Akita H, et al: 18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy. Mol Clin Oncol 8: 434-440, 2018.
APA
Yano, M., Miyata, H., Sugimura, K., Motoori, M., Omori, T., Fujiwara, Y. ... Sakon, M. (2018). 18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy. Molecular and Clinical Oncology, 8, 434-440. https://doi.org/10.3892/mco.2018.1546
MLA
Yano, M., Miyata, H., Sugimura, K., Motoori, M., Omori, T., Fujiwara, Y., Miyoshi, N., Yasui, M., Ohue, M., Akita, H., Tomokuni, A., Takahashi, H., Kobayashi, S., Sakon, M."18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy". Molecular and Clinical Oncology 8.3 (2018): 434-440.
Chicago
Yano, M., Miyata, H., Sugimura, K., Motoori, M., Omori, T., Fujiwara, Y., Miyoshi, N., Yasui, M., Ohue, M., Akita, H., Tomokuni, A., Takahashi, H., Kobayashi, S., Sakon, M."18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy". Molecular and Clinical Oncology 8, no. 3 (2018): 434-440. https://doi.org/10.3892/mco.2018.1546
Copy and paste a formatted citation
x
Spandidos Publications style
Yano M, Miyata H, Sugimura K, Motoori M, Omori T, Fujiwara Y, Miyoshi N, Yasui M, Ohue M, Akita H, Akita H, et al: 18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy. Mol Clin Oncol 8: 434-440, 2018.
APA
Yano, M., Miyata, H., Sugimura, K., Motoori, M., Omori, T., Fujiwara, Y. ... Sakon, M. (2018). 18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy. Molecular and Clinical Oncology, 8, 434-440. https://doi.org/10.3892/mco.2018.1546
MLA
Yano, M., Miyata, H., Sugimura, K., Motoori, M., Omori, T., Fujiwara, Y., Miyoshi, N., Yasui, M., Ohue, M., Akita, H., Tomokuni, A., Takahashi, H., Kobayashi, S., Sakon, M."18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy". Molecular and Clinical Oncology 8.3 (2018): 434-440.
Chicago
Yano, M., Miyata, H., Sugimura, K., Motoori, M., Omori, T., Fujiwara, Y., Miyoshi, N., Yasui, M., Ohue, M., Akita, H., Tomokuni, A., Takahashi, H., Kobayashi, S., Sakon, M."18F‑fluorodeoxyglucose positron emission tomography̸computed tomography for the prediction of survival in patients with advanced esophageal cancer who have undergone neoadjuvant chemotherapy". Molecular and Clinical Oncology 8, no. 3 (2018): 434-440. https://doi.org/10.3892/mco.2018.1546
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