Duodenal mucinous adenocarcinoma presenting as ileus, obstructive jaundice and massive ascites: A case report

Ding,Dongbing; Yao,Yao; Zhang,Songbai

doi:10.3892/mco.2018.1552

March-2018 Volume 8 Issue 3

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March-2018 Volume 8 Issue 3

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Case Report

Duodenal mucinous adenocarcinoma presenting as ileus, obstructive jaundice and massive ascites: A case report

Authors:
- Dongbing Ding
- Yao Yao
- Songbai Zhang
View Affiliations / Copyright

Affiliations: Department of Gastrointestinal Surgery, Jingmen First People's Hospital, Jingmen, Hubei 448000, P.R. China, Department of Ophthalmology, Jingmen First People's Hospital, Jingmen, Hubei 448000, P.R. China
Pages: 441-444
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Published online on: January 11, 2018

https://doi.org/10.3892/mco.2018.1552
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Abstract

Duodenal mucinous adenocarcinoma (DMA) is a malignancy with a rather low morbidity. However, its incidence in China has not been clearly determined. We herein report a case of a 70‑year‑old female patient who presented with ileus, obstructive jaundice and massive ascites simultaneously. Gastroendoscopy revealed copious amounts of colloidal mucin in the gastric cavity. The neoplasm was not visualized on computed tomography or magnetic resonance imaging, and an exploratory laparotomy was performed to investigate the abdomen. During the operation, the anterior wall of the gastric antrum was incised to explore the first and second portions of the duodenum, as well as the gastric lumen, and a neoplasm sized ~2.0 cm was identified at the antimesenteric border of the duodenal bulb after clearing the colloidal mucin content of the stomach and duodenum. Gastrojejunostomy rather than radical resection was performed due to the poor condition of the patient. The postoperative histopathological examination of the colloidal substance removed from the duodenal cavity revealed mucinous adenocarcinoma. On immunohistochemical analysis, the tissue stained positive for pan‑cytokeratin, cytokeratin 19, CDX‑2, carcinoembryonic antigen and Ki‑67 (8%), and negative for excision repair‑1. The general condition of the patient postoperatively was poor; thus, adjuvant chemotherapy was not administered and the patient finally succumbed to the disease 42 days after surgery.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Duodenal mucinous adenocarcinoma presenting as ileus, obstructive jaundice and massive ascites: A case report

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