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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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July-2018 Volume 9 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Case Report

Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review

  • Authors:
    • Jawaher Ansari
    • Enas Batubara
    • Muhammad Ali
    • Ashraf Farrag
    • Farhat Bashir
    • Hussein R. Farghaly
    • Arwa M. Ali
    • Arif Shaukat
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia, Department of Pulmonology, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia, Department of Nuclear Medicine Division, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia
  • Pages: 92-95
    |
    Published online on: May 4, 2018
       https://doi.org/10.3892/mco.2018.1620
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Abstract

Erlotinib is a first‑generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) approved in the first‑line treatment of advanced non‑small‑cell lung cancer (NSCLC) patients with sensitizing epidermal growth factor receptor (EGFR) mutations. The response rate to erlotinib is ~60% and the incidence of erlotinib‑induced interstitial lung disease (ILD) is ~1‑4%. The Response Evaluation Criteria in Solid Tumours (RECIST) tool is commonly used to assess response to erlotinib; however, evaluation of response and subsequent progression in the presence of atypical cystic lung changes may be challenging. We herein present a rare case of diffuse cystic lung changes secondary to erlotinib treatment in a patient with EGFR mutation‑positive metastatic NSCLC. Challenges in assessing atypical tumour response to erlotinib, pitfalls in using RECIST and differential diagnosis of TKI‑related ILD are discussed in detail.
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Copy and paste a formatted citation
Spandidos Publications style
Ansari J, Batubara E, Ali M, Farrag A, Bashir F, Farghaly HR, Ali AM and Shaukat A: Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review. Mol Clin Oncol 9: 92-95, 2018.
APA
Ansari, J., Batubara, E., Ali, M., Farrag, A., Bashir, F., Farghaly, H.R. ... Shaukat, A. (2018). Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review. Molecular and Clinical Oncology, 9, 92-95. https://doi.org/10.3892/mco.2018.1620
MLA
Ansari, J., Batubara, E., Ali, M., Farrag, A., Bashir, F., Farghaly, H. R., Ali, A. M., Shaukat, A."Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review". Molecular and Clinical Oncology 9.1 (2018): 92-95.
Chicago
Ansari, J., Batubara, E., Ali, M., Farrag, A., Bashir, F., Farghaly, H. R., Ali, A. M., Shaukat, A."Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review". Molecular and Clinical Oncology 9, no. 1 (2018): 92-95. https://doi.org/10.3892/mco.2018.1620
Copy and paste a formatted citation
x
Spandidos Publications style
Ansari J, Batubara E, Ali M, Farrag A, Bashir F, Farghaly HR, Ali AM and Shaukat A: Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review. Mol Clin Oncol 9: 92-95, 2018.
APA
Ansari, J., Batubara, E., Ali, M., Farrag, A., Bashir, F., Farghaly, H.R. ... Shaukat, A. (2018). Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review. Molecular and Clinical Oncology, 9, 92-95. https://doi.org/10.3892/mco.2018.1620
MLA
Ansari, J., Batubara, E., Ali, M., Farrag, A., Bashir, F., Farghaly, H. R., Ali, A. M., Shaukat, A."Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review". Molecular and Clinical Oncology 9.1 (2018): 92-95.
Chicago
Ansari, J., Batubara, E., Ali, M., Farrag, A., Bashir, F., Farghaly, H. R., Ali, A. M., Shaukat, A."Atypical diffuse bilateral cystic lung changes secondary to erlotinib treatment in a patient with metastatic non‑small cell lung carcinoma: A case report and literature review". Molecular and Clinical Oncology 9, no. 1 (2018): 92-95. https://doi.org/10.3892/mco.2018.1620
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