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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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October-2018 Volume 9 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

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Case Report

Intra-articular synovial sarcoma in the ankle joint: A case report

  • Authors:
    • Tomoki Nakamura
    • Tomohito Hagi
    • Kunihiro Asanuma
    • Akihiro Sudo
  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan
  • Pages: 464-466
    |
    Published online on: August 20, 2018
       https://doi.org/10.3892/mco.2018.1702
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Abstract

Intra-articular primary soft tissue sarcomas are extremely rare. The present case report describes a case of intra-articular synovial sarcoma of the ankle joint. A 51-year‑old man presented with complaints of swelling and progressive pain in the right ankle. Lateral radiographs of the ankle revealed lytic invasion of the anterior and posterior parts of the talus. Computed tomography imaging revealed a low-density lesion with calcifications around the ankle joint. Magnetic resonance imaging revealed that the diffuse lesion was isointense on T1-weighted images and hypointense to hyperintense on T2-weighted images. The final diagnosis was synovial sarcoma. The foot could not be salvaged as the sarcoma was diffusely spread throughout the ankle joint; thus, the patient underwent below-the-knee amputation with neoadjuvant and adjuvant chemotherapy. He succumbed from fatal arrhythmia 2 years following the initial diagnosis. Although intra-articular primary soft tissue sarcomas are extremely rare, the possibility of malignancy should be considered.
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1 

Friedman MV, Kyriakos M, Matava MJ, McDonald DJ, Jennings JW and Wessell DE: Intra-articular synovial sarcoma. Skeletal Radiol. 42:859–867. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Chebib I, Rosenberg AE, Fletcher CDM, Rosenthal DI, Hornicek FJ and Nielsen GP: Primary intra-articular sarcoma: A clinicopathological study of 15 cases. Histopathology. 69:614–623. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Nordemar D, Öberg J, Brosjö O and Skorpil M: Intra-articular synovial sarcomas: Incident and differentiating features from localized pigmented villonodular synovitis. Sarcoma. 2015:9038732015. View Article : Google Scholar : PubMed/NCBI

4 

Weiss SW and Goldblum JR: Enzinger and Weiss's soft tissue tumors. 5th. Elsevier; St Louis: pp. 1161–1182. 2008

5 

Morton MJ, Berquist TH, McLeod RA, Unni KK and Sim FH: MR imaging of synovial sarcoma. AJR Am J Roentgenol. 156:337–340. 1991. View Article : Google Scholar : PubMed/NCBI

6 

Cadman NL, Soule EH and Kelly PJ: Synovial sarcoma: An analysis of 134 tumors. Cancer. 18:613–627. 1965. View Article : Google Scholar : PubMed/NCBI

7 

Murphry MD, Rhee JH, Fanburg-Smith LJC, Flemming DJ and Walker EA: From the archives of the AFIP pigmented villonodular synovitis: Radiologic-pathologic correlation. Radiographics. 28:1493–1518. 2009. View Article : Google Scholar

8 

Oda Y, Izumi T, Harimaya K, Segawa Y, Ishihara S, Komune S, Iwamoto Y and Tsuneyoshi M: Pigmented villonodular synovitis with chondroid metaplasia, resembling chondroblastoma of the bone: A report of three cases. Mod Pathol. 20:545–551. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Bui-Mansfield LT and O'Brien SD: Magnetic resonance appearance of intra-articular synovial sarcoma: Case reports and review of the literature. J Comput Assist Tomogr. 32:640–644. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Saxena A and St Louis M: Synovial chondromatosis of the ankle: Report of two cases with 23 and 126 loose bodies. J Foot Ankle Surg. 56:182–186. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Derek Stensby J, Fox MG, Kwon MS, Cavcedo FJ and Rahimi A: Primary synovial chondromatosis of subtalar joint: Case report and review of the literature. Skeletal Radiol. 47:391–396. 2017. View Article : Google Scholar : PubMed/NCBI

12 

Bhamra JS, Alorjani M, Skinner JA and Saifuddin A: Intra-articular extraskeletal myxoid chondrosarcoma of the ankle. Skeletal Radiol. 41:1017–1020. 2012. View Article : Google Scholar : PubMed/NCBI

13 

Biazzo A and Confalonieri N: Synovial chondrosarcoma. Ann Transl Med. 4:2802016. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Nakamura T, Hagi T, Asanuma K and Sudo A: Intra-articular synovial sarcoma in the ankle joint: A case report. Mol Clin Oncol 9: 464-466, 2018.
APA
Nakamura, T., Hagi, T., Asanuma, K., & Sudo, A. (2018). Intra-articular synovial sarcoma in the ankle joint: A case report. Molecular and Clinical Oncology, 9, 464-466. https://doi.org/10.3892/mco.2018.1702
MLA
Nakamura, T., Hagi, T., Asanuma, K., Sudo, A."Intra-articular synovial sarcoma in the ankle joint: A case report". Molecular and Clinical Oncology 9.4 (2018): 464-466.
Chicago
Nakamura, T., Hagi, T., Asanuma, K., Sudo, A."Intra-articular synovial sarcoma in the ankle joint: A case report". Molecular and Clinical Oncology 9, no. 4 (2018): 464-466. https://doi.org/10.3892/mco.2018.1702
Copy and paste a formatted citation
x
Spandidos Publications style
Nakamura T, Hagi T, Asanuma K and Sudo A: Intra-articular synovial sarcoma in the ankle joint: A case report. Mol Clin Oncol 9: 464-466, 2018.
APA
Nakamura, T., Hagi, T., Asanuma, K., & Sudo, A. (2018). Intra-articular synovial sarcoma in the ankle joint: A case report. Molecular and Clinical Oncology, 9, 464-466. https://doi.org/10.3892/mco.2018.1702
MLA
Nakamura, T., Hagi, T., Asanuma, K., Sudo, A."Intra-articular synovial sarcoma in the ankle joint: A case report". Molecular and Clinical Oncology 9.4 (2018): 464-466.
Chicago
Nakamura, T., Hagi, T., Asanuma, K., Sudo, A."Intra-articular synovial sarcoma in the ankle joint: A case report". Molecular and Clinical Oncology 9, no. 4 (2018): 464-466. https://doi.org/10.3892/mco.2018.1702
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