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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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November-2018 Volume 9 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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Case Report

Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report

  • Authors:
    • Blanca Gil‑Ibañez
    • Purificacion Regueiro
    • Elisa Llurba
    • Lorena Fariñas‑Madrid
    • Angel Garcia
    • Berta Diaz‑Feijoo
  • View Affiliations / Copyright

    Affiliations: Unit of Gynecological Oncology, Institute Clinic of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic of Barcelona, 08036 Barcelona, Spain, Department of Obstetrics and Gynecology, General Hospital of Hospitalet, 08906 Barcelona, Spain, Department of Obstetrics and Gynecology, Sant Pau University Hospital, Autonomous University of Barcelona, 08041 Barcelona, Spain, Department of Oncology, Vall d'Hebron Institute of Oncology (VHIO), 08035 Barcelona, Spain, Department of Pathology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain, Unit of Gynecological Oncology, Department of Obstetrics and Gynecology, Hospital Materno‑Infantil Vall d'Hebron, Autonomous University of Barcelona, 08035 Barcelona, Spain
  • Pages: 519-522
    |
    Published online on: September 13, 2018
       https://doi.org/10.3892/mco.2018.1717
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Abstract

Large‑cell neuroendocrine carcinoma (LCNEC) is an uncommon histological subtype of cervical cancer that is associated with poor survival and its occurrence during pregnancy is particularly rare. We herein present the case of a female patient who was diagnosed with cervical LCNEC during pregnancy. The patient declined pregnancy termination and was treated with neoadjuvant chemotherapy with cisplatin and etoposide, without associated toxicity and with good fetal development. At 31.4 weeks of gestation, the fetus was delivered by caesarean section, and the patient underwent radical nerve‑sparing hysterectomy with bilateral adnexectomy, along with pelvic and inframesenteric para‑aortic lymphadenectomy. The patient received adjuvant chemoradiotherapy and there was no evidence of recurrence or metastasis at 38 months postoperatively. The baby has also been followed up, without any signs of neurodevelopmental disorders. To the best of our knowledge, the present report describes the first case of LCNEC with pregnancy‑preserving management in the literature to date.
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Copy and paste a formatted citation
Spandidos Publications style
Gil‑Ibañez B, Regueiro P, Llurba E, Fariñas‑Madrid L, Garcia A and Diaz‑Feijoo B: Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report. Mol Clin Oncol 9: 519-522, 2018.
APA
Gil‑Ibañez, B., Regueiro, P., Llurba, E., Fariñas‑Madrid, L., Garcia, A., & Diaz‑Feijoo, B. (2018). Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report. Molecular and Clinical Oncology, 9, 519-522. https://doi.org/10.3892/mco.2018.1717
MLA
Gil‑Ibañez, B., Regueiro, P., Llurba, E., Fariñas‑Madrid, L., Garcia, A., Diaz‑Feijoo, B."Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report". Molecular and Clinical Oncology 9.5 (2018): 519-522.
Chicago
Gil‑Ibañez, B., Regueiro, P., Llurba, E., Fariñas‑Madrid, L., Garcia, A., Diaz‑Feijoo, B."Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report". Molecular and Clinical Oncology 9, no. 5 (2018): 519-522. https://doi.org/10.3892/mco.2018.1717
Copy and paste a formatted citation
x
Spandidos Publications style
Gil‑Ibañez B, Regueiro P, Llurba E, Fariñas‑Madrid L, Garcia A and Diaz‑Feijoo B: Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report. Mol Clin Oncol 9: 519-522, 2018.
APA
Gil‑Ibañez, B., Regueiro, P., Llurba, E., Fariñas‑Madrid, L., Garcia, A., & Diaz‑Feijoo, B. (2018). Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report. Molecular and Clinical Oncology, 9, 519-522. https://doi.org/10.3892/mco.2018.1717
MLA
Gil‑Ibañez, B., Regueiro, P., Llurba, E., Fariñas‑Madrid, L., Garcia, A., Diaz‑Feijoo, B."Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report". Molecular and Clinical Oncology 9.5 (2018): 519-522.
Chicago
Gil‑Ibañez, B., Regueiro, P., Llurba, E., Fariñas‑Madrid, L., Garcia, A., Diaz‑Feijoo, B."Challenges in the management of neuroendocrine cervical cancer during pregnancy: A case report". Molecular and Clinical Oncology 9, no. 5 (2018): 519-522. https://doi.org/10.3892/mco.2018.1717
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