Live birth following laparoscopic fertility‑sparing surgery for papillary thyroid carcinoma arising from mature ovarian cystic teratoma: A case report

Iwahashi,Naoyuki; Deguchi,Yoko; Horiuchi,Yuko; Noguchi,Tomoko; Yahata,Tamaki; Ota,Nami; Ino,Kazuhiko; Furukawa,Kenichi

doi:10.3892/mco.2018.1743

December-2018 Volume 9 Issue 6

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December-2018 Volume 9 Issue 6

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Case Report Open Access

Live birth following laparoscopic fertility‑sparing surgery for papillary thyroid carcinoma arising from mature ovarian cystic teratoma: A case report

Authors:
- Naoyuki Iwahashi
- Yoko Deguchi
- Yuko Horiuchi
- Tomoko Noguchi
- Tamaki Yahata
- Nami Ota
- Kazuhiko Ino
- Kenichi Furukawa
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynecology, Hashimoto Municipal Hospital, Hashimoto, Wakayama 648‑0005, Japan, Department of Obstetrics and Gynecology, Wakayama Medical University, Wakayama, Wakayama 641‑0012, Japan

Copyright: © Iwahashi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 613-616
|
Published online on: October 5, 2018

https://doi.org/10.3892/mco.2018.1743
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Abstract

Papillary thyroid carcinoma arising from ovarian mature cystic teratoma is clinically rare. We herein present a case of live birth following two laparoscopic surgeries for papillary thyroid carcinoma arising in a mature ovarian cystic teratoma. A 30‑year‑old female patient, gravida 1 para 1, was treated by laparoscopic bilateral ovarian cystectomy for suspicion of bilateral mature cystic teratoma. The diagnosis of papillary thyroid carcinoma arising from right ovarian mature cystic teratoma was established based on postoperative pathological examination of the tumor. Such rare neoplasms may be difficult to diagnose preoperatively based on radiological examinations alone. The patient underwent laparoscopic fertility‑preserving unilateral (right) salpingo‑oophorectomy. Following an extensive discussion with the patient and her family, appropriate informed consent was obtained for the treatment option and the patient and her family chose to preserve her fertility. She could have a baby following the treatment and no evidence of disease for 6 years. Gynecologists should be aware of the possibility of such rare cases, and the available surgical interventions should be fully discussed with patients who wish to preserve their fertility. Laparoscopic fertility‑sparing surgery may be a feasible option when encountering such a rare condition.

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1	Lai PF, Hsieh SC, Chien JC, Fang CL, Chan WP and Yu C: Malignant transformation of an ovarian mature cystic teratoma: Computed tomography findings. Arch Gynecol Obstet. 271:355–357. 2005. View Article : Google Scholar : PubMed/NCBI
2	Wen KC, Hu WM, Twu NF, Chen P and Wang PH: Poor prognosis of intraoperative rupture of mature cystic teratoma with malignant transformation. Taiwan J Obstet Gynecol. 45:253–256. 2006. View Article : Google Scholar : PubMed/NCBI
3	Kido A, Togashi K, Konishi I, Kataoka ML, Koyama T, Ueda H, Fujii S and Konishi J: Dermoid cysts of the ovary with malignant transformation: MR appearance. AJR Am J Roentgenol. 172:445–449. 1999. View Article : Google Scholar : PubMed/NCBI
4	Mori Y, Nishii H, Takabe K, Shinozaki H, Matsumoto N, Suzuki K, Tanabe H, Watanabe A, Ochiai K and Tanaka T: Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary. Gynecol Oncol. 90:338–341. 2003. View Article : Google Scholar : PubMed/NCBI
5	Lataifeh I, Abdel-Hadi M, Morcos B, Sughayer M and Barahmeh S: Papillary thyroid carcinoma arising from mature cystic teratoma of the ovary. J Obstet Gynaecol. 30:884–886. 2010. View Article : Google Scholar : PubMed/NCBI
6	Peterson WF: Malignant degeneration of benign cystic teratomas of the overy; a collective review of the literature. Obstet Gynecol Surv. 12:793–830. 1957. View Article : Google Scholar : PubMed/NCBI
7	Dane C, Ekmez M, Karaca A, Ak A and Dane B: Follicular variant of papillary thyroid carcinoma arising from a dermoid cyst: A rare malignancy in young women and review of the literature. Taiwan J Obstet Gynecol. 51:421–425. 2012. View Article : Google Scholar : PubMed/NCBI
8	Soto Moreno A, Venegas EM, Rodriguez JR, Sánchez F, Robles MJ, Martinez MA, Gonzalez D, Navarro E and Astorga R: Thyroid carcinoma on an ovarian teratoma: A case report and review of the literature. Gynecol Endocrinol. 16:207–211. 2002. View Article : Google Scholar : PubMed/NCBI
9	Lee JM, Kim JW, Song JY, Lee JK, Lee NW, Kim SH and Lee KW: Adenocarcinoma arising in mature cystic teratoma: A case report. J Gynecol Oncol. 19:199–201. 2008. View Article : Google Scholar : PubMed/NCBI
10	Cymbaluk-Ploska A, Chudecka-Głaz A, Chosia M, Ashuryk O and Menkiszak J: Conservative treatment of a young patient with thyroid carcinoma in adult ovarian teratoma-case report. Gynecol Endocrinol. 30:187–191. 2014. View Article : Google Scholar : PubMed/NCBI
11	Chadha S and Schaberg A: Malignant transformation in benign cystic teratomas: Dermoids of the ovary. Eur J Obstet Gynecol Reprod Biol. 29:329–338. 1988. View Article : Google Scholar : PubMed/NCBI
12	Doldi N, Taccagni GL, Bassan M, Frigerio L, Mangili G, Jansen AM and Ferrari A: Hashimoto's disease in a papillary carcinoma of the thyroid originating in a teratoma of the ovary (malignant struma ovarii). Gynecol Endocrinol. 12:41–42. 1998. View Article : Google Scholar : PubMed/NCBI
13	Bal A, Mohan H, Singh SB and Sehgal A: Malignant transformation in mature cystic teratoma of the ovary: Report of five cases and review of the literature. Arch Gynecol Obstet. 275:179–182. 2007. View Article : Google Scholar : PubMed/NCBI
14	Ryder M, Nikiforov YE and Fagin JA: Follicular variant papillary thyroid carcinoma arising within an ovarian teratoma. Thyroid. 17:179–180. 2007. View Article : Google Scholar : PubMed/NCBI
15	Quadri AM, Ganesan R, Hock YL, Karim SN and Hirschowitz L: Malignant transformation in mature cystic teratoma of the ovary: Three cases mimicking primary ovarian epithelial tumors. Int J Surg Pathol. 19:718–723. 2011. View Article : Google Scholar : PubMed/NCBI
16	Tanaka H, Sakakura Y, Kobayashi T, Yoshida K, Asakura T and Taniguchi H: A case of thyroid-type papillary carcinoma derived from ovarian mature cystic teratoma, resected by laparoscopic surgery. Asian J Endosc Surg. 4:86–89. 2011. View Article : Google Scholar : PubMed/NCBI
17	Lipson SA and Hricak H: MR imaging of the female pelvis. Radiol Clin North Am. 34:1157–1182. 1996.PubMed/NCBI
18	Rim SY, Kim SM and Choi HS: Malignant transformation of ovarian mature cystic teratoma. Int J Gynecol Cancer. 16:140–144. 2006. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Live birth following laparoscopic fertility‑sparing surgery for papillary thyroid carcinoma arising from mature ovarian cystic teratoma: A case report

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