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The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer

  • Authors:
    • Chiyo Maeda
    • Shungo Endo
    • Yuichi Mori
    • Shumpei Mukai
    • Eiji Hidaka
    • Fumio Ishida
    • Shin-Ei Kudo
  • View Affiliations / Copyright

    Affiliations: Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Kanagawa 224-8503, Japan
    Copyright: © Maeda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 425-429
    |
    Published online on: February 26, 2019
       https://doi.org/10.3892/mco.2019.1815
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Abstract

Positron emission tomography/computed tomography (PET/CT) is frequently used to detect colorectal cancer. The present retrospective study assessed the ability of PET/CT to identify synchronous colonic lesions in 72 patients with obstructive colorectal cancer. All patients had undergone surgical resection without undergoing preoperative total colonoscopy (TCS) at the Digestive Disease Center (April 2007 to September 2016), and subsequently underwent TCS of the proximal colon within 2 years post‑surgery. A total of 11 patients exhibited 18F‑fluorodeoxyglucose uptake during PET/CT of the proximal colon (4 invasive cancers, 3 advanced adenomas and 4 false‑positive results), and 61 patients had no uptake in the proximal colon. Among these 61 patients, postoperative TCS revealed 2 invasive cancers and 4 advanced adenomas. The sensitivity of PET/CT for detecting synchronous invasive cancers was 66.6% (4/6), with a specificity of 89.4% (59/66), a positive predictive value of 36.4% (4/11), a negative predictive value of 96.7% (59/61), and an accuracy of 87.5% (63/72). Negative PET/CT results indicated a low probability of synchronous lesions in the proximal colon. Thus, PET/CT may be a useful tool for detecting synchronous colonic cancers in patients with obstructive colon cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Maeda C, Endo S, Mori Y, Mukai S, Hidaka E, Ishida F and Kudo S: The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer. Mol Clin Oncol 10: 425-429, 2019.
APA
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., & Kudo, S. (2019). The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer. Molecular and Clinical Oncology, 10, 425-429. https://doi.org/10.3892/mco.2019.1815
MLA
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., Kudo, S."The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer". Molecular and Clinical Oncology 10.4 (2019): 425-429.
Chicago
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., Kudo, S."The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer". Molecular and Clinical Oncology 10, no. 4 (2019): 425-429. https://doi.org/10.3892/mco.2019.1815
Copy and paste a formatted citation
x
Spandidos Publications style
Maeda C, Endo S, Mori Y, Mukai S, Hidaka E, Ishida F and Kudo S: The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer. Mol Clin Oncol 10: 425-429, 2019.
APA
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., & Kudo, S. (2019). The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer. Molecular and Clinical Oncology, 10, 425-429. https://doi.org/10.3892/mco.2019.1815
MLA
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., Kudo, S."The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer". Molecular and Clinical Oncology 10.4 (2019): 425-429.
Chicago
Maeda, C., Endo, S., Mori, Y., Mukai, S., Hidaka, E., Ishida, F., Kudo, S."The ability of positron emission tomography/computed tomography to detect synchronous colonic cancers in patients with obstructive colorectal cancer". Molecular and Clinical Oncology 10, no. 4 (2019): 425-429. https://doi.org/10.3892/mco.2019.1815
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