Long‑term outcome following sentinel node navigation surgery for cT1 gastric cancer

Yaguchi,Yoshihisa; Tsujimoto,Hironori; Hiraki,Shuichi; Ito,Nozomi; Nomura,Shinsuke; Horiguchi,Hiroyuki; Kumano,Isao; Einama,Takahiro; Okamoto,Koichi; Noro,Takuji; Kajiwara,Yoshiki; Shinto,Eiji; Aosasa,Suefumi; Ichikura,Takashi; Ueno,Hideki

doi:10.3892/mco.2019.1833

June-2019 Volume 10 Issue 6

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June-2019 Volume 10 Issue 6

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Article

Long‑term outcome following sentinel node navigation surgery for cT1 gastric cancer

Authors:
- Yoshihisa Yaguchi
- Hironori Tsujimoto
- Shuichi Hiraki
- Nozomi Ito
- Shinsuke Nomura
- Hiroyuki Horiguchi
- Isao Kumano
- Takahiro Einama
- Koichi Okamoto
- Takuji Noro
- Yoshiki Kajiwara
- Eiji Shinto
- Suefumi Aosasa
- Takashi Ichikura
- Hideki Ueno
View Affiliations / Copyright

Affiliations: Department of Surgery, National Defense Medical College, Tokorozawa, Saitama 359‑8513, Japan
Pages: 615-618
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Published online on: March 28, 2019

https://doi.org/10.3892/mco.2019.1833
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Abstract

Sentinel node navigation surgery (SNNS) has become a standard procedure for early‑stage melanoma and breast cancer. However, very few studies have evaluated the long‑term clinical outcomes following SNNS for gastric cancer. The present study analyzed 51 patients with cT1 gastric cancer who underwent SNNS at our hospital. Sentinel nodes (SNs) were identiﬁed using the dual tracer method. Patients underwent limited gastrectomy with SN station dissection when the SNs were reported as pathologically negative during surgery. When SNs were pathologically positive, standard gastrectomy with D2 lymphadenectomy was performed. Out of the 51 cases, 42 cases (82%) were pathologically diagnosed as SN‑negative using a frozen section. The surgical procedures included segmental gastrectomy (n=33) and local resection (n=9). A total of 9 patients (18%) had lymph node metastasis in SNs. The mean observation period was 3,125±167 days, and the 5‑year overall survival rate was 98%. There was no recurrence, and body weight loss was minimal following the SNNS. Remnant gastric cancer developed in 4 (8%) of the 50 patients except total gastrectomy. Thus, SNNS was a useful procedure for cT1 gastric cancer from the long‑term clinical outcomes, though metachronous gastric cancer should paid further attention to.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Long‑term outcome following sentinel node navigation surgery for cT1 gastric cancer

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