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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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June-2019 Volume 10 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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Case Report Open Access

Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report

  • Authors:
    • Yoshihisa Tokumaru
    • Nobuhisa Matsuhashi
    • Takao Takahashi
    • Toshiyuki Tanahashi
    • Satoshi Matsui
    • Hisashi Imai
    • Yoshihiro Tanaka
    • Kazuya Yamaguchi
    • Kazuhiro Yoshida
  • View Affiliations / Copyright

    Affiliations: Department of Surgical Oncology, Gifu University School of Medicine, Gifu, Gifu 501‑1194, Japan
    Copyright: © Tokumaru et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 571-574
    |
    Published online on: April 3, 2019
       https://doi.org/10.3892/mco.2019.1836
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Abstract

The combination of cetuximab (CTX) and chemotherapy, such as FOLFOX or FOLFIRI, is currently the standard treatment for metastatic colorectal cancer (mCRC). Zoledronic acid (ZOL) is used in patients with bone metastasis. We herein report our experience with the case of a 58‑year‑old male patient with metastatic rectal cancer who was treated with ZOL + CTX as third‑line therapy, and in whom this combination appeared to be effective. Although the patient developed bone metastasis and cardiac tamponade due to the recurrence of rectal cancer, he survived for approximately 10 months after the initiation of ZOL and CTX treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Tokumaru Y, Matsuhashi N, Takahashi T, Tanahashi T, Matsui S, Imai H, Tanaka Y, Yamaguchi K and Yoshida K: Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report. Mol Clin Oncol 10: 571-574, 2019.
APA
Tokumaru, Y., Matsuhashi, N., Takahashi, T., Tanahashi, T., Matsui, S., Imai, H. ... Yoshida, K. (2019). Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report. Molecular and Clinical Oncology, 10, 571-574. https://doi.org/10.3892/mco.2019.1836
MLA
Tokumaru, Y., Matsuhashi, N., Takahashi, T., Tanahashi, T., Matsui, S., Imai, H., Tanaka, Y., Yamaguchi, K., Yoshida, K."Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report". Molecular and Clinical Oncology 10.6 (2019): 571-574.
Chicago
Tokumaru, Y., Matsuhashi, N., Takahashi, T., Tanahashi, T., Matsui, S., Imai, H., Tanaka, Y., Yamaguchi, K., Yoshida, K."Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report". Molecular and Clinical Oncology 10, no. 6 (2019): 571-574. https://doi.org/10.3892/mco.2019.1836
Copy and paste a formatted citation
x
Spandidos Publications style
Tokumaru Y, Matsuhashi N, Takahashi T, Tanahashi T, Matsui S, Imai H, Tanaka Y, Yamaguchi K and Yoshida K: Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report. Mol Clin Oncol 10: 571-574, 2019.
APA
Tokumaru, Y., Matsuhashi, N., Takahashi, T., Tanahashi, T., Matsui, S., Imai, H. ... Yoshida, K. (2019). Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report. Molecular and Clinical Oncology, 10, 571-574. https://doi.org/10.3892/mco.2019.1836
MLA
Tokumaru, Y., Matsuhashi, N., Takahashi, T., Tanahashi, T., Matsui, S., Imai, H., Tanaka, Y., Yamaguchi, K., Yoshida, K."Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report". Molecular and Clinical Oncology 10.6 (2019): 571-574.
Chicago
Tokumaru, Y., Matsuhashi, N., Takahashi, T., Tanahashi, T., Matsui, S., Imai, H., Tanaka, Y., Yamaguchi, K., Yoshida, K."Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report". Molecular and Clinical Oncology 10, no. 6 (2019): 571-574. https://doi.org/10.3892/mco.2019.1836
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