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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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August-2019 Volume 11 Issue 2

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Case Report

Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report

  • Authors:
    • Hiroshi Yaegashi
    • Suguru Kadomoto
    • Renato Naito
    • Tomoyuki Makino
    • Hiroaki Iwamoto
    • Takahiro Nohara
    • Kazuyoshi Shigehara
    • Kouji Izumi
    • Yoshifumi Kadono
    • Atsushi Mizokami
  • View Affiliations / Copyright

    Affiliations: Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa 920‑8640, Japan
  • Pages: 139-142
    |
    Published online on: May 22, 2019
       https://doi.org/10.3892/mco.2019.1865
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Abstract

Urachal cancer often presents at an advanced stage with poor prognosis due to the lack of an effective systematic therapeutic strategy. We experienced a case of metastatic urachal cancer treated effectively by combination chemotherapy and radiotherapy. A 55‑year‑old female presented to our department with right lower abdominal pain. A transurethral biopsy of an urachal tumor suggested urachal adenocarcinoma. The patient underwent chemotherapy with gemcitabine and cisplatin for metastatic urachal cancer. As tumor markers declined and the radiological findings indicated stability of disease, external beam radiotherapy was then administered to the primary site. Chemotherapy was then administered again in response to tumor markers gradually increasing and the progression of multiple peritoneal metastases. However, the patient did not complete chemotherapy due to hematological toxicity. The patient succumbed to primary disease 23 months after initial diagnosis. Previous studies have reported that the median time from the diagnosis of metastatic urachal cancer to mortality is just over 1 year. By contrast, in the present case the patient survived up to 2 years with combination chemotherapy and radiotherapy, a rare incidence worthy of reporting.
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Copy and paste a formatted citation
Spandidos Publications style
Yaegashi H, Kadomoto S, Naito R, Makino T, Iwamoto H, Nohara T, Shigehara K, Izumi K, Kadono Y, Mizokami A, Mizokami A, et al: Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report. Mol Clin Oncol 11: 139-142, 2019.
APA
Yaegashi, H., Kadomoto, S., Naito, R., Makino, T., Iwamoto, H., Nohara, T. ... Mizokami, A. (2019). Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report. Molecular and Clinical Oncology, 11, 139-142. https://doi.org/10.3892/mco.2019.1865
MLA
Yaegashi, H., Kadomoto, S., Naito, R., Makino, T., Iwamoto, H., Nohara, T., Shigehara, K., Izumi, K., Kadono, Y., Mizokami, A."Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report". Molecular and Clinical Oncology 11.2 (2019): 139-142.
Chicago
Yaegashi, H., Kadomoto, S., Naito, R., Makino, T., Iwamoto, H., Nohara, T., Shigehara, K., Izumi, K., Kadono, Y., Mizokami, A."Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report". Molecular and Clinical Oncology 11, no. 2 (2019): 139-142. https://doi.org/10.3892/mco.2019.1865
Copy and paste a formatted citation
x
Spandidos Publications style
Yaegashi H, Kadomoto S, Naito R, Makino T, Iwamoto H, Nohara T, Shigehara K, Izumi K, Kadono Y, Mizokami A, Mizokami A, et al: Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report. Mol Clin Oncol 11: 139-142, 2019.
APA
Yaegashi, H., Kadomoto, S., Naito, R., Makino, T., Iwamoto, H., Nohara, T. ... Mizokami, A. (2019). Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report. Molecular and Clinical Oncology, 11, 139-142. https://doi.org/10.3892/mco.2019.1865
MLA
Yaegashi, H., Kadomoto, S., Naito, R., Makino, T., Iwamoto, H., Nohara, T., Shigehara, K., Izumi, K., Kadono, Y., Mizokami, A."Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report". Molecular and Clinical Oncology 11.2 (2019): 139-142.
Chicago
Yaegashi, H., Kadomoto, S., Naito, R., Makino, T., Iwamoto, H., Nohara, T., Shigehara, K., Izumi, K., Kadono, Y., Mizokami, A."Metastatic urachal cancer treated effectively with gemcitabine/cisplatin combination chemotherapy and radiotherapy: A case report". Molecular and Clinical Oncology 11, no. 2 (2019): 139-142. https://doi.org/10.3892/mco.2019.1865
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