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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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August-2019 Volume 11 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Case Report

Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report

  • Authors:
    • Ruo‑Lan Gu
    • Ming Xiang
    • Jing Suo
    • Jing Yuan
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China
  • Pages: 135-138
    |
    Published online on: June 12, 2019
       https://doi.org/10.3892/mco.2019.1877
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Abstract

This case report describes a case of an unusual initial presentation of acute lymphoblastic leukemia in a previously healthy 15‑year‑old boy. He initially presented with a 6‑day history of tiredness, decreased oral intake, nausea, vomiting, and jaundice (yellow sclera and dark urine) with evidence of acute hepatic failure, presenting as an increase in alanine aminotransferase (ALT)/aspartate aminotransferase (AST)/total bilirubin and a decrease in prothrombin activity. A complete serological evaluation for liver disease was negative. The levels of serum AST and ALT declined following hepatoprotective treatment. Bone marrow biopsy was diagnostic, revealing 68.15% blasts with markers consistent with acute B‑cell lymphoblastic leukemia. This case report emphasizes that acute hepatic failure may be the initial presentation of ALL in an adolescent.
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Copy and paste a formatted citation
Spandidos Publications style
Gu RL, Xiang M, Suo J and Yuan J: Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report. Mol Clin Oncol 11: 135-138, 2019.
APA
Gu, R., Xiang, M., Suo, J., & Yuan, J. (2019). Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report. Molecular and Clinical Oncology, 11, 135-138. https://doi.org/10.3892/mco.2019.1877
MLA
Gu, R., Xiang, M., Suo, J., Yuan, J."Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report". Molecular and Clinical Oncology 11.2 (2019): 135-138.
Chicago
Gu, R., Xiang, M., Suo, J., Yuan, J."Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report". Molecular and Clinical Oncology 11, no. 2 (2019): 135-138. https://doi.org/10.3892/mco.2019.1877
Copy and paste a formatted citation
x
Spandidos Publications style
Gu RL, Xiang M, Suo J and Yuan J: Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report. Mol Clin Oncol 11: 135-138, 2019.
APA
Gu, R., Xiang, M., Suo, J., & Yuan, J. (2019). Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report. Molecular and Clinical Oncology, 11, 135-138. https://doi.org/10.3892/mco.2019.1877
MLA
Gu, R., Xiang, M., Suo, J., Yuan, J."Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report". Molecular and Clinical Oncology 11.2 (2019): 135-138.
Chicago
Gu, R., Xiang, M., Suo, J., Yuan, J."Acute lymphoblastic leukemia in an adolescent presenting with acute hepatic failure: A case report". Molecular and Clinical Oncology 11, no. 2 (2019): 135-138. https://doi.org/10.3892/mco.2019.1877
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