Dedifferentiated liposarcoma of the thyroid gland: A case report

Kishimoto,Yo; Ohno Kishimoto,Ayami; Yamada,Yosuke; Kitano,Masayuki; Kitada,Yuji; Kitamura,Morimasa; Tateya,Ichiro; Sonobe,Makoto; Omori,Koichi

doi:10.3892/mco.2019.1882

September-2019 Volume 11 Issue 3

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September-2019 Volume 11 Issue 3

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Case Report Open Access

Dedifferentiated liposarcoma of the thyroid gland: A case report

Authors:
- Yo Kishimoto
- Ayami Ohno Kishimoto
- Yosuke Yamada
- Masayuki Kitano
- Yuji Kitada
- Morimasa Kitamura
- Ichiro Tateya
- Makoto Sonobe
- Koichi Omori
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Affiliations: Department of Otolaryngology‑Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan, Department of Diagnosic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan, Department of Diagnostic Pathology, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan, Department of Otolaryngology‑Head and Neck Surgery, Japanese Red Cross Osaka Hospital, Osaka 543‑8555, Japan, Department of Otolaryngology‑Head and Neck Surgery, Kitano Hospital Tazuke Medical Research Institute, Osaka 530‑8480, Japan, Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan

Copyright: © Kishimoto et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 219-224
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Published online on: June 18, 2019

https://doi.org/10.3892/mco.2019.1882
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Abstract

Liposarcoma is one of the most common soft tissue tumors that affect adults. Liposarcoma is typically identified in the retroperitoneum, trunk and extremities as a slow‑growing mass, yet is rare in the thyroid gland. Herein, we report a case of dedifferentiated liposarcoma that developed in the thyroid gland, and performed a literature review. A 66‑year‑old male with a history of well‑differentiated liposarcoma in the thymus presented with a rapidly enlarging mass in the thyroid gland. Malignancy was suspected due to the local extension of the tumor, and complete resection of the tumor was achieved. Tissue diagnosis from the tumor following surgery revealed that dedifferentiated liposarcoma, and tumor progression was difficult to control with adjuvant radiation and chemotherapy. This is, to the best of our knowledge, the first case to report dedifferentiated liposarcoma in the thyroid gland, and the difficulty in initial diagnosis as well as the aggressive features of dedifferentiated liposarcoma are highlighted.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Dedifferentiated liposarcoma of the thyroid gland: A case report

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