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Article

Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer

  • Authors:
    • Jian Li
    • Dan‑Dan Wang
    • Yu‑Nian Zhao
    • Jian‑Wei Zhou
    • Jin‑Hai Tang
  • View Affiliations / Copyright

    Affiliations: The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu 210000, P.R. China, Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Department of Molecular Cell Biology and Toxicology, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, P.R. China
  • Pages: 411-415
    |
    Published online on: August 2, 2019
       https://doi.org/10.3892/mco.2019.1905
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Abstract

The aim of the present study was to investigate the efficacy of magnetic resonance imaging (MRI)‑guided radiofrequency ablation (RFA) for breast cancer patients who cannot undergo traditional surgery. A total of 10 patients were treated by MRI‑guided RFA, of whom 6 had stage IV disease (lung metastasis n=3, bone metastasis n=1, liver metastasis n=1 and mediastinal metastasis n=1) and the remaining 4 patients, who refused surgery, had stage III disease accompanied by severe underlying conditions. The changes in feasibility, tumor volume, bleeding, local recurrence, metastasis and complications were evaluated after RFA. The patients were followed up at 1, 3, 6 and 12 months, and annually thereafter. A total of 14 RFA sessions were successfully performed (100%) in the 10 patients, among whom 7 patients underwent a single RFA session, 2 patients underwent two sessions, and 1 patient underwent three sessions. Compared with pre‑RFA, the volume of the tumors at 6 months after RFA was markedly decreased. There was no local tumor recurrence or metastasis detected during a mean follow‑up period of 19.5±3.46 months, and no major complications were reported. Therefore, RFA was found to be a minimally invasive and feasible treatment method in the present study, and MRI‑guided RFA may be a promising alternative option for breast cancer patients who are unable to tolerate surgery. However, more prospective studies on the applicability of RFA in breast cancer are required.
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Copy and paste a formatted citation
Spandidos Publications style
Li J, Wang DD, Zhao YN, Zhou JW and Tang JH: Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer. Mol Clin Oncol 11: 411-415, 2019.
APA
Li, J., Wang, D., Zhao, Y., Zhou, J., & Tang, J. (2019). Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer. Molecular and Clinical Oncology, 11, 411-415. https://doi.org/10.3892/mco.2019.1905
MLA
Li, J., Wang, D., Zhao, Y., Zhou, J., Tang, J."Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer". Molecular and Clinical Oncology 11.4 (2019): 411-415.
Chicago
Li, J., Wang, D., Zhao, Y., Zhou, J., Tang, J."Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer". Molecular and Clinical Oncology 11, no. 4 (2019): 411-415. https://doi.org/10.3892/mco.2019.1905
Copy and paste a formatted citation
x
Spandidos Publications style
Li J, Wang DD, Zhao YN, Zhou JW and Tang JH: Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer. Mol Clin Oncol 11: 411-415, 2019.
APA
Li, J., Wang, D., Zhao, Y., Zhou, J., & Tang, J. (2019). Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer. Molecular and Clinical Oncology, 11, 411-415. https://doi.org/10.3892/mco.2019.1905
MLA
Li, J., Wang, D., Zhao, Y., Zhou, J., Tang, J."Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer". Molecular and Clinical Oncology 11.4 (2019): 411-415.
Chicago
Li, J., Wang, D., Zhao, Y., Zhou, J., Tang, J."Clinical assessment of magnetic resonance imaging‑guided radiofrequency ablation for breast cancer". Molecular and Clinical Oncology 11, no. 4 (2019): 411-415. https://doi.org/10.3892/mco.2019.1905
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